目次
原著論文
2013年｜2012年｜2011年｜2010年｜2009年｜2008年｜2007年｜2006年
2013年
- Katayama, R., Aoyama, A., Yamori, T., Qi, J., Oh-hara, T., Song, Y., Engelman, J.A., Fujita, N.
- Cytotoxic activity of Tivantinib (ARQ 197) is not due solely to c-MET inhibition.
Cancer Res, in press (2013) - Yamada, T., Takeuchi, S., Fujita, N., Nakamura, A., Wang, W., Li, Q., Oda, M., Mitsudomi, T., Yatabe, Y., Sekido, Y., Yoshida, J., Higashiyama, M., Noguchi, M., Uehara, H., Nishioka, Y., Sone, S., Yano, S.
- Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations.
Oncogene, in press (2012)
2012年
- Fujita, N., Takagi, S.
- The impact of Aggrus/podoplanin on platelet aggregation and tumor metastasis.
J Biochem, 152, 407-413 (2012) - Hahne, J.C., Honig, A., Meyer, S.R., Gambaryan, S., Walter, U., Wischhusen, J., Haussler, S.F., Segerer, S.E., Fujita, N., Dietl, J., Engel, J.B.
- Downregulation of AKT reverses platinum resistance of human ovarian cancers in vitro.
Oncol Rep, 28, 2023-2028 (2012) - Mohanty, A.R., Kan, Q., Srivastava, S., Uranbileg, B., Arakawa-Takeuchi, S., Fujita, N., Okayama, H.
- Successive phosphorylation of p27Kip1 protein at serine-10 and C-terminus crucially controls its cotency to inactivate cdk2.
J Biol Chem, 287, 21757-21764 (2012)
2011年
- Ehata, S., Johansson, E., Katayama, R., Koike, S., Watanabe, A., Hoshino, Y., Katsuno, Y., Komuro, A., Koinuma, D., Kano, M.R., Yashiro, M., Hirakawa, K., Aburatani, H., Fujita, N., Miyazono, K.
- Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells.
Oncogene, 30, 1693-1705 (2011) - Konishi, S., Yasuchika, K., Ishii, T., Fukumitsu, K., Kamo, N., Fujita, N., Ikai, I., Uemoto, S.
- A transmembrane glycoprotein, gp38, is a novel marker for immature hepatic progenitor cells in fetal mouse livers.
In Vitro Cell Dev Biol Anim, 47, 45-53 (2011) - Morishita, D., Takami, M., Yoshikawa, S., Katayama, R., Sato, S., Kukimoto-Niino, M., Umehara, T., Shirouzu, M., Sekimizu, K., Yokoyama, S., Fujita, N.
- Cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
J Biol Chem, 286, 2681-2688 (2011) - Nakazawa, Y., Arai, H., Fujita, N.
- The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis.
Cancer Res, 71, 1146-1155 (2011) - Nakazawa, Y., Takagi, S., Sato, S., Oh-Hara, T., Koike, S., Takami, M., Arai, H., Fujita, N.
- Prevention of hematogenous metastasis by neutralizing mice and its chimeric anti-Aggrus/podoplanin antibodies.
Cancer Sci, 102, 2051-2057 (2011)
2010年
- Katayama, R., Ishioka, T., Takada, S., Takada, R., Fujita, N., Tsuruo, T., Naito, M.
- Modulation of Wnt signaling by the nuclear localization of cellular FLIP-L.
J Cell Sci, 123, 23-28 (2010) - Misawa, A., Katayama, R., Koike, S., Tomida, A., Watanabe, T., Fujita, N.
- AP-1-Dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells.
Oncol Res, 19, 23-33 (2010) - Nakamura, A., Naito, M., Arai, H., Fujita, N.
- Mitotic phosphorylation of Aki1 at Ser208 by cyclin B1-Cdk1 complex.
Biochem Biophys Res Commun, 393, 872-876 (2010) - Péterfy, M., Harris, T.E., Fujita, N., Reue, K.
- Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
J Biol Chem, 285, 3857-3864 (2010)
2009年
- Demers, M.J., Thibodeau, S., Noel, D., Fujita, N., Tsuruo, T., Gauthier, R., Arguin, M., Vachon, P.H.
- Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1.
J Cell Biochem, 107, 639-654 (2009) - Katayama, R., Koike, S., Sato, S., Sugimoto, Y., Tsuruo, T., Fujita, N.
- Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.
Cancer Sci, 100, 2060-2068 (2009) - Nakamura, A., Arai, H., Fujita, N.
- Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement.
J Cell Biol, 187, 607-614 (2009) - Tanaka, H., Hoshikawa, Y., Oh-hara, T., Koike, S., Naito, M., Noda, T., Arai, H., Tsuruo, T., Fujita, N.
- PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-κB activation.
Mol Cancer Res, 7, 557-569 (2009)
2008年
- Bouchard, V., Harnois, C., Demers, M.J., Thibodeau, S., Laquerre, V., Gauthier, R., Vezina, A., Noel, D., Fujita, N., Tsuruo, T., Arguin, M., Vachon, P.H.
- β1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms.
Apoptosis, 13, 531-542 (2008) - Katayama, K., Nakamura, A., Sugimoto, Y., Tsuruo, T., Fujita, N.
- FOXO transcription factor-dependent p15INK4b and p19INK4d expression.
Oncogene, 27, 1677-1686 (2008) - Kurata, A., Katayama, R., Watanabe, T., Tsuruo, T., Fujita, N.
- TUSC4/NPRL2, a novel PDK1-interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling.
Cancer Sci, 99, 1827-1834 (2008) - Morishita, D., Katayama, R., Sekimizu, K., Tsuruo, T., Fujita, N.
- Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.
Cancer Res, 68, 5076-5085 (2008) - Nakamura, A., Naito, M., Tsuruo, T., Fujita, N.
- Freud-1/Aki1, a novel PDK1-interacting protein, functions as a scaffold to activate the PDK1/Akt pathway in epidermal growth factor signaling.
Mol Cell Biol, 28, 5996-6009 (2008) - Nakasaki, T., Tanaka, T., Okudaira, S., Hirosawa, M., Umemoto, E., Otani, K., Jin, S., Bai, Z., Hayasaka, H., Fukui, Y., Aozasa, K., Fujita, N., Tsuruo, T., Ozono, K., Aoki, J., Miyasaka, M.
- Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions.
Am J Pathol, 173, 1566-1576 (2008) - Nakazawa, Y., Sato, S., Naito, M., Kato, Y., Mishima, K., Arai, H., Tsuruo, T., Fujita, N.
- Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis.
Blood, 112, 1730-1739 (2008)
2007年
- Bouchard, V., Demers, M.J., Thibodeau, S., Laquerre, V., Fujita, N., Tsuruo, T., Beaulieu, J.F., Gauthier, R., Vezina, A., Villeneuve, L., Vachon, P.H.
- Fak/Src signaling in human intestinal epithelial cell survival and anoikis: differentiation state-specific uncoupling with the PI3-K/Akt-1 and MEK/Erk pathways.
J Cell Physiol, 212, 717-728 (2007) - Kamo, N., Yasuchika, K., Fujii, H., Hoppo, T., Machimoto, T., Ishii, T., Fujita, N., Tsuruo, T., Yamashita, J.K., Kubo, H., Ikai, I.
- Two populations of Thy1-positive mesenchymal cells regulate in vitro maturation of hepatic progenitor cells.
Am J Physiol Gastrointest Liver Physiol, 292, G526-534 (2007) - Kunita, A., Kashima, T.G., Morishita, Y., Fukayama, M., Kato, Y., Tsuruo, T., Fujita, N.
- The platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasis.
Am J Pathol, 170, 1337-1347 (2007) - Rosner, M., Freilinger, A., Hanneder, M., Fujita, N., Lubec, G., Tsuruo, T., Hengstschläger, M.
- p27Kip1 localization depends on the tumor suppressor protein tuberin.
Hum Mol Genet, 16, 1541-1556 (2007) - Tokuda, E., Fujita, N., Oh-hara, T., Sato, S., Kurata, A., Katayama, R., Itoh, T., Takenawa, T., Miyazono, K., Tsuruo, T.
- Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.
Cancer Res, 67, 9666-9676 (2007)
2006年
- Dai, J., Bai, J., Hasegawa, T., Nishizawa, S., Sakai, J., Oka, S., Kiuchi, M., Hirose, K., Tomida, A., Tsuruo, T., Li, M., Ando, M.
- A new taxoid from a callus culture of Taxus cuspidata as an MDR reversal agent.
Chem Pharm Bull (Tokyo), 54, 306-309 (2006) - Kono, T., Kubo, H., Shimazu, C., Ueda, Y., Takahashi, M., Yanagi, K., Fujita, N., Tsuruo, T., Wada, H., Yamashita, J.K.
- Differentiation of lymphatic endothelial cells from embryonic stem cells on OP9 stromal cells.
Arterioscler Thromb Vasc Biol, 26, 2070-2076 (2006) - Li, N., Wu, J.L., Hasegawa, T., Sakai, J., Wang, L.Y., Kakuta, S., Furuya, Y., Tomida, A., Tsuruo, T., Ando, M.
- Bioactive dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii.
J Nat Prod, 69, 234-239 (2006) - Mishima, K., Kato, Y., Kaneko, M.K., Nakazawa, Y., Kunita, A., Fujita, N., Tsuruo, T., Nishikawa, R., Hirose, T., Matsutani, M.
- Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma.
Acta Neuropathol, 111, 563-568 (2006) - Tahara, H., Shin-Ya, K., Seimiya, H., Yamada, H., Tsuruo, T., Ide, T.
- G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
Oncogene, 25, 1955-1966 (2006) - Wu, J.L., Li, N., Hasegawa, T., Sakai, J., Mitsui, T., Ogura, H., Kataoka, T., Oka, S., Kiuchi, M., Tomida, A., Tsuruo, T., Li, M., Tang, W., Ando, M.
- Bioactive secolignans from Peperomia dindygulensis.
J Nat Prod, 69, 790-794 (2006)
