目次
原著論文
2013年｜2012年｜2011年｜2010年｜2009年｜2008年｜2007年｜2006年｜2005年
2013年
- Ushijima, M., Mashima, T., Tomida, A., Dan, S., Saito, S., Furuno, A., Tsukahara, S., Seimiya, H., Yamori, T., Matsuura, M.
- Development of a gene expression database and related analysis programs for evaluation of anticancer compounds.
Cancer Sci, 104, 360-368 (2013) - Iida, K., Majima, S., Nakamura, T., Seimiya, H., Nagasawa, K.
- Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand.
Molecules, in press (2013) - Migita, T., Okabe, S., Ikeda, K., Igarashi, S., Sugawara, S., Tomida, A., Taguchi, R., Soga, T., Seimiya, H.
- Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact.
Am J Pathol, in press (2013)
2012年
- Deardorff, M.A., Bando, M., Nakato, R., Watrin, E., Itoh, T., Minamino, M., Saitoh, K., Komata, M., Katou, Y., Clark, D., Cole, K.E., De Baere, E., Decroos, C., Di Donato, N., Ernst, S., Francey, L.J., Gyftodimou, Y., Hirashima, K., Hullings, M., Ishikawa, Y., Jaulin, C., Kaur, M., Kiyono, T., Lombardi, P.M., Magnaghi-Jaulin, L., Mortier, G.R., Nozaki, N., Petersen, M.B., Seimiya, H., Siu, V.M., Suzuki, Y., Takagaki, K., Wilde, J.J., Willems, P.J., Prigent, C., Gillessen-Kaesbach, G., Christianson, D.W., Kaiser, F.J., Jackson, L.G., Hirota, T., Krantz, I.D., Shirahige, K.
- HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle.
Nature, 489, 313-317 (2012) - Ha, G.H., Kim, H.S., Go, H., Lee, H., Seimiya, H., Chung, D.H., Lee, C.W.
- Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation.
Cell Death Differ, 19, 321-332 (2012) - Kawahara, T., Hosoya, T., Tsukamoto, M., Okabe, S., Yamamura, H., Hayakawa, M., Seimiya, H., Takagi, M., Shin-Ya, K.
- JBIR-120: a new growth inhibitor of hormone-refractory prostate cancer cells.
J Antibiot, 65, 373-375 (2012) - Miyazaki, T., Pan, Y., Joshi, K., Purohit, D., Hu, B., Demir, H., Mazumder, S., Okabe, S., Yamori, T., Viapiano, M., Shin-ya, K., Seimiya, H., Nakano, I.
- Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.
Clin Cancer Res, 18, 1268-1280 (2012) - Nakamura, T., Iida, K., Tera, M., Shin-Ya, K., Seimiya, H., Nagasawa, K.
- A caged ligand for a telomeric g-quadruplex.
Chembiochem, 13, 774-777 (2012)
2011年
- Mashima, T., Okabe, S., Seimiya, H.
- Molecular pharmacological approach reveals potential new strategies to suppress androgen receptor signaling in prostate cancer.
Mol Cell Pharmacol, 3, 7-12 (2011) - Mashima, T., Seimiya, H.
- Role of acyl-CoA synthetases in glioma cell survival and its therapeutic implication.
In Tumors of the central nervous system, Hayat, M.A.e., (Heidelberg, Springer,), 337-340 (2011) - Takahashi, K., Imano, R., Kibe, T., Seimiya, H., Muramatsu, Y., Kawabata, N., Tanaka, G., Matsumoto, Y., Hiromoto, T., Koizumi, Y., Nakazawa, N., Yanagida, M., Yukawa, M., Tsuchiya, E., Ueno, M.
- Fission yeast pot1 and recQ helicase are required for efficient chromosome segregation.
Mol Cell Biol, 31, 495-506 (2011)
2010年
- Hatsugai, K., Ohishi, T., Sugimoto, Y., Seimiya, H.
- Tankyrase-1 assembly to large protein complexes blocks its telomeric function.
FEBS Lett, 584, 3885-3890 (2010) - Kobayashi, Y., Sato, K., Kibe, T., Seimiya, H., Nakamura, A., Yukawa, M., Tsuchiya, E., Ueno, M.
- Expression of mutant RPA in human cancer cells causes telomere shortening.
Biosci Biotechnol Biochem, 74, 382-385 (2010) - Mashima, T., Okabe, S., Seimiya, H.
- Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth.
Mol Pharmacol, 78, 846-854 (2010) - Migita, T., Narita, T., Asaka, R., Miyagi, E., Nagano, H., Nomura, K., Matsuura, M., Satoh, Y., Okumura, S., Nakagawa, K., Seimiya, H., Ishikawa, Y.
- Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3.
Am J Pathol, 176, 1756-1766 (2010) - Ohishi, T., Hirota, T., Tsuruo, T., Seimiya, H.
- TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression.
Cancer Res, 70, 2041-2052 (2010) - Seki, T., Yuasa, S., Oda, M., Egashira, T., Yae, K., Kusumoto, D., Nakata, H., Tohyama, S., Hashimoto, H., Kodaira, M., Okada, Y., Seimiya, H., Fusaki, N., Hasegawa, M., Fukuda, K.
- Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells.
Cell Stem Cell, 7, 11-14 (2010) - Tera, M., Iida, K., Ikebukuro, K., Seimiya, H., Shin-Ya, K., Nagasawa, K.
- Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole.
Org Biomol Chem, 8, 2749-2755 (2010) - Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H., Yoshida, M.
- A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor.
Biochem Biophys Res Commun, 394, 569-573 (2010)
2009年
- Mashima, T., Sato, S., Okabe, S., Miyata, S., Matsuura, M., Sugimoto, Y., Tsuruo, T., Seimiya, H.
- Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.
Cancer Sci, 100, 1556-1562 (2009) - Mashima, T., Sato, S., Sugimoto, Y., Tsuruo, T., Seimiya, H.
- Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions.
Oncogene, 28, 9-19 (2009) - McCabe, N., Cerone, M.A., Ohishi, T., Seimiya, H., Lord, C.J., Ashworth, A.
- Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer.
Oncogene, 28, 1465-1470 (2009) - Schulz, R., Vogel, T., Mashima, T., Tsuruo, T., Krieglstein, K.
- Involvement of fractin in TGF-β-induced apoptosis in oligodendroglial progenitor cells.
Glia, 57, 1619-1629 (2009)
2008年
- Migita, T., Narita, T., Nomura, K., Miyagi, E., Inazuka, F., Matsuura, M., Ushijima, M., Mashima, T., Seimiya, H., Satoh, Y., Okumura, S., Nakagawa, K., Ishikawa, Y.
- ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
Cancer Res, 68, 8547-8554 (2008) - Muramatsu, Y., Tahara, H., Ono, T., Tsuruo, T., Seimiya, H.
- Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.
Exp Cell Res, 314, 1115-1124 (2008) - Yeung, B.H., Wong, K.Y., Lin, M.C., Wong, C.K., Mashima, T., Tsuruo, T., Wong, A.S.
- Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2.
Br J Cancer, 99, 283-293 (2008)
2007年
- Muramatsu, Y., Ohishi, T., Sakamoto, M., Tsuruo, T., Seimiya, H.
- Cross-species difference in telomeric function of tankyrase 1.
Cancer Sci, 98, 850-857 (2007) - Ohishi, T., Tsuruo, T., Seimiya, H.
- Evaluation of tankyrase inhibition in whole cells.
Methods Mol Biol, 405, 133-146 (2007) - Tanaka, E., Fukuda, H., Nakashima, K., Tsuchiya, N., Seimiya, H., Nakagama, H.
- HnRNP A3 binds to and protects mammalian telomeric repeats in vitro.
Biochem Biophys Res Commun, 358, 608-614 (2007)
2006年
- Kimura, H., Katoh, T., Kajimoto, T., Node, M., Hisaki, M., Sugimoto, Y., Majima, T., Uehara, Y., Yamori, T.
- Modification of pyrimidine derivatives from antiviral agents to antitumor agents.
Anticancer Res, 26, 91-97 (2006) - Tahara, H., Shin-Ya, K., Seimiya, H., Yamada, H., Tsuruo, T., Ide, T.
- G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
Oncogene, 25, 1955-1966 (2006)
2005年
- Seimiya, H., Muramatsu, Y., Ohishi, T., Tsuruo, T.
- Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.
Cancer Cell, 7, 25-37 (2005)
