Recent Publications

Recent Publications

2017 | 2016 | 2015 | 2014 | 2013

2016

Dec 26, 2016
Koido, M., Haga, N., Furuno, A., Tsukahara, S., Sakurai, J., Tani, Y., Sato, S. and Tomida, A.
Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth .
Oncotarget, 8, 11841-854 (2017)
Dec 19, 2016
Sakha, S., Muramatsu, T., Ueda, K., Inazawa, J.
Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma
Sci Rep, in press (2016)
Dec 15, 2016
Sakakibara, R., Inamura, K., Tambo, Y., Ninomiya, H., Kitazono, S., Yanagitani, N., Horiike, A., Ohyanagi, F., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Inase, N., Nishio, M., Motoi, N., Ishikawa, Y.
EBUS-TBNA as a promising method for the evaluation of tumor PD-L1 expression in lung cancer.
Clin Lung Cancer, in press (2016)
Dec 15, 2016
Mori, S., Motoi, N., Ninomiya, H., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Nishio, M., Morikawa, T., Ishikawa, Y.
High expression of programmed cell death 1 ligand 1 in lung adenocarcinoma is a poor prognostic factor particularly in smokers and wild-type epidermal growth-factor receptor cases.
Pathol Int, in press (2016)
Dec 12, 2016
Nagasawa, I., Kunimasa, K., Tsukahara, S., Tomida, A.
BRAF-mutated cells activate GCN2-mediated integrated stress response as a cytoprotective mechanism in response to vemurafenib.
Biochem Biophys Res Commun, in press (2016)
Dec 08, 2016
Tanaka, M., Homme, M., Yamazaki, Y., Shimizu, R., Takazawa, Y., Nakamura, T.
Modeling alveolar soft part sarcoma unveils novel mechanisms of metastasis.
Cancer Res, in press (2016)
Oct 04, 2016
Koido, M., Sakurai, J., Tsukahara, S., Tani, Y., Tomida, A.
PMEPA1, a TGF-β- and hypoxia-inducible gene that participates in hypoxic gene expression networks in solid tumors.
Biochem Biophys Res Commun, in press (2016)
Aug 24, 2016
Kurita, D., Takeuchi, K., Kobayashi, S., Hojo, A., Uchino, Y., Sakagami, M., Ohtake, S., Takahashi, H., Miura, K., Iriyama, N., Sugitani, M., Miyoshi, H., Hatta, Y., Ohshima, K., Takei, M.
A cyclin D1-negative mantle cell lymphoma with an IGL-CCND2 translocation that relapsed with blastoid morphology and aggressive clinical behavior.
Virchows Archiv, in press (2016)
Aug 24, 2016
Kataoka, K., Shiraishi, Y., Takeda, Y., Sakata, S., Matsumoto, M., Nagano, S., Maeda, T., Nagata, Y., Kitanaka, A., Mizuno, S., Tanaka, H., Chiba, K., Ito, S., Watatani, Y., Kakiuchi, N., Suzuki, H., Yoshizato, T., Yoshida, K., Sanada, M., Itonaga, H., Imaizumi, Y., Totoki, Y., Munakata, W., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Masuda, K., Minato, N., Kashiwase, K., Izutsu, K., Takaori-Kondo, A., Miyazaki, Y., Takahashi, S., Shibata, T., Kawamoto, H., Akatsuka, Y., Shimoda, K., Takeuchi, K., Seya, T., Miyano, S., Ogawa, S.
Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.
Nature, 534, 402-406 (2016)
Aug 09, 2016
Hattori, T., Watanabe-Takahashi, M., Shiina, I., Ohashi, Y., Dan, S., Nishikawa, K., Yamori, T., Naito, M.
M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin.
Genes to cells : devoted to molecular & cellular mechanisms, 21, 901-906 (2016)
Aug 09, 2016
Narita, K., Matsuhara, K., Itoh, J., Akiyama, Y., Dan, S., Yamori, T., Ito, A., Yoshida, M., Katoh, T.
Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors.
Eur J Med Chem, 121, 592-609 (2016)
Aug 09, 2016
Ohashi, Y., Okamura, M., Hirosawa, A., Tamaki, N., Akatsuka, A., Wu, K.M., Choi, H.W., Yoshimatsu, K., Shiina, I., Yamori, T., Dan, S.
M-COPA, a golgi disruptor, inhibits cell surface expression of MET protein and exhibits antitumor activity against MET-addicted gastric cancers.
Cancer Res, 76, 3895-3903 (2016)
Aug 09, 2016
Akatsuka, A., Kojima, N., Okamura, M., Dan, S., Yamori, T.
A novel thiophene-3-carboxamide analog of annonaceous acetogenin exhibits antitumor activity via inhibition of mitochondrial complex I.
Pharmacology Research & Perspectives, 4, e00246 (2016)
Jul 21, 2016
Gainor, J.F., Dardaei, L., Yoda, K., Friboulet, L., Leshchiner, I., Katayama, R., Dagogo-Jack, I., Gadgeel, S.M., Schultz, K., Singh, M., Chin, E., Parks, M., Lee, D., DiCecca, R.H., Lockerman, E., Huynh, T., Logan, J., Ritterhouse, L.L., Le, L., P., Muniappan, A., Digumarthy, S., Channick, C., Keyes, C., Getz, G., Dias-Santagata, D., Heist, R.S., Lennerz, J., Sequist, L.V., Benes, C.H., Iafrate, A.J., Mino-Kenudson, M., Engelman, J.A., Shaw, A.T.
Molecular mechanisms of resistance to first- and second-generation ALK inhibitors in ALK-rearranged lung cancer.
Cancer Discov, in press (2016)
Jul 13, 2016
Abe, Y., Hirota, T.
System-level deficiencies in Aurora B control in cancers.
Cell Cycle, in press (2016)
Jul 13, 2016
Nagasaka, K., Hossain, M.J., Roberti, M.J., Ellenberg, J., Hirota, T.
Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.
Nat Cell Biol, 18, 692-699 (2016)
Jul 13, 2016
Takahashi, M., Tanaka, K., Wakai, T., Hirota, T.
Phosphoproteomic analysis of human mitotic chromosomes identified a chromokinesin KIF4A.
Biomed Res, 37, 161-165 (2016)
Jul 13, 2016
Tanaka, K., Hirota, T.
Chromosomal instability: A common feature and a therapeutic target of cancer.
Biochimica et biophysica acta, 1866, 64-75 (2016)
May 24, 2016
Kusano, H., Togashi, Y., Akiba, J., Moriya, F., Baba, K., Matsuzaki, N., Yuba, Y., Shiraishi, Y., Kanamaru, H., Kuroda, N., Sakata, S., Takeuchi, K., Yano, H.
Two cases of renal cell carcinoma harboring a novel STRN-ALK fusion gene.
Am J Surg Pathol, in press (2016)
May 24, 2016
Kataoka, K., Shiraishi, Y., Takeda, Y., Sakata, S., Matsumoto, M., Nagano, S., Maeda, T., Nagata, Y., Kitanaka, A., Mizuno, S., Tanaka, H., Chiba, K., Ito, S., Watatani, Y., Kakiuchi, N., Suzuki, H., Yoshizato, T., Yoshida, K., Sanada, M., Itonaga, H., Imaizumi, Y., Totoki, Y., Munakata, W., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Masuda, K., Minato, N., Kashiwase, K., Izutsu, K., Takaori-Kondo, A., Miyazaki, Y., Takahashi, S., Shibata, T., Kawamoto, H., Akatsuka, Y., Shimoda, K., Takeuchi, K., Seya, T., Miyano, S., Ogawa, S.
Aberrant PD-L1 expression via 3’-UTR disruption in multiple cancers.
Nature, in press (2016)
May 20, 2016
Toki, H., Minowa, O., Inoue, M., Motegi, H., Karashima, Y., Ikeda, A., Kaneda, H., Sakuraba, Y., Saiki, Y., Wakana, S., Suzuki, H., Gondo, Y., Shiroishi, T., Noda, T.
Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Biochem Biophys Res Commun, in press (2016)
May 20, 2016
Nakagawa, A., Naito, A.T., Sumida, T., Nomura, S., Shibamoto, M., Higo, T., Okada, K., Sakai, T., Hashimoto, A., Kuramoto, Y., Oka, T., Lee, J.K., Harada, M., Ueda, K., Shiojima, I., Limbourg, F.P., Adams, R.H., Noda, T., Sakata, Y., Akazawa, H., Komuro, I.
Activation of endothelial beta-catenin signaling induces heart failure.
Sci Rep, 6, 25009 (2016)
May 17, 2016
Suenaga, M., Mashima, T., Kawata, N., Wakatsuki, T., Horiike, Y., Matsusaka, S., Dan, S., Shinozaki, E., Seimiya, H., Mizunuma, N., Yamaguchi, K., Yamaguch, T.
Serum VEGF-A and CCL5 levels as candidate biomarkers for efficacy and toxicity of regorafenib in patients with metastatic colorectal cancer.
Oncotarget, in press (2016)
Apr 18, 2016
Abe, Y., Sako, K., Takagaki, K., Hirayama, Y., Uchida, K.S., Herman, J.A., DeLuca, J.G., Hirota, T.
HP1-Assisted Aurora B Kinase Activity Prevents Chromosome Segregation Errors.
Dev Cell, 36, 487-497 (2016)
Mar 18, 2016
Nakamura, T., Ma, Y., Iida, K., Ohtake, T., Seimiya, H., Nagasawa, K.
Design, synthesis and evaluation of an L-Dopa-derived macrocyclic hexaoxazole (6OTD) as a G-quadruplex-selective ligand.
Heterocycles, in press (2016)
Mar 18, 2016
Mizutani, A., Koinuma, D., Seimiya, H., Miyazono, K.
The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma.
Oncogene, in press (2015)
Feb 09, 2016
Kusano, H., Togashi, Y., Akiba, J., Moriya, F., Baba, K., Matsuzaki, N., Yuba, Y., Shiraishi, Y., Kanamaru, H., Kuroda, N., Sakata, S., Takeuchi, K., Yano, H.
Two cases of renal cell carcinoma harboring a novel STRN-ALK fusion gene.
Am J Surg Pathol, in press (2016)
Jan 26, 2016
Horiike, A., Takeuchi, K., Uenami, T., Kawano, Y., Tanioto, A., Kaburaki, K., Tambo, Y., Kudo, K., Yanagitani, N., Ohyanagi, F., Motoi, N., Ishikawa, Y., Horai, T., Nishio, M.
Sorafenib treatment for patients with RET fusion-positive non-small cell lung cancer.
Lung Cancer, 93, 43-46 (2016)
Jan 19, 2016
Dobashi, A., Tsuyama, N., Asaka, R., Togashi, Y., Ueda, K., Sakata, S., Baba, S., Sakamoto, K., Hatake, K., Takeuchi, K.
Frequent BCOR Aberrations in Extranodal NK/T-Cell Lymphoma, Nasal Type.
Genes Chromosomes Cancer, in press (2016)
Jan 19, 2016
Sakamoto, K., Nakasone, H., Togashi, Y., Sakata, S., Tsuyama, N., Baba, S., Dobashi, A., Asaka, R., Tsai, C.C., Chuang, S.S., Izutsu, K., Kanda, Y., Takeuch, K.
ALK-positive large B cell lymphoma: identification of EML4-ALK and a review of the literature focusing on the ALK immunohistochemical staining pattern.
Int J Hematol, in press (2016)
Jan 12, 2016
Shimoda, A., Ueda, K., Nishiumi, S., Murata-Kamiya, N., Mukai, S.A., Sawada, S., Azuma, T., Hatakeyama, M., Akiyoshi, K.
Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
Sci Rep, 6, 18346 (2016)

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