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The CANCER INSTITUTE of the Japanese Foundation for Cancer Research
Department of Protein Engineering
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Overview
Since its establishment in August of 2001, the Department of Protein Engineering has been dedicated to developing important proteinous biopharmaceuticals and nanoscale biomaterials through the use of our proprietary technology, MolCraft.
MolCraft is a novel type of in vitro protein evolution system, in which we first encrypt the desired functions or structures into a designer microgene as peptide motifs, and then construct a protein library by polymerization of the microgene. With MolCraft as the core competency, we are coordinating the following projects.
Projects
(1) Enhancement of the biocompatibility of titanous materials using artificial proteins.
(2) Development of carbon nanohorn-based drug delivery system.
(3) Rewiring signal networks using artificial signal proteins.
(4) Genetic control of mineralization.
(5) Understanding the relationships between the structure and function of proteins.
Chief Kiyotaka Shiba
Postdoctoral Scientist Sachiko Matsumura, Shohei Kaneda, Katsutoshi Kokubun
Visiting Ph.D. Student Kazuhiko Hashimoto
Visiting Scientist Daisuke Kase, Mizue Saze
Staff Technician Tamiko Minamisawa
Technician Kanako Suga
Management Assistant Kumiko Winterberg
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