| 2016年12月26日 |
Koido, M., Haga, N., Furuno, A., Tsukahara, S., Sakurai, J., Tani, Y., Sato, S. and Tomida, A. Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth
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Oncotarget, 8, 11841-854 (2017) |
| 2016年12月19日 |
Sakha, S., Muramatsu, T., Ueda, K., Inazawa, J. Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma
Sci Rep, in press (2016) |
| 2016年12月15日 |
Sakakibara, R., Inamura, K., Tambo, Y., Ninomiya, H., Kitazono, S., Yanagitani, N., Horiike, A., Ohyanagi, F., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Inase, N., Nishio, M., Motoi, N., Ishikawa, Y. EBUS-TBNA as a promising method for the evaluation of tumor PD-L1 expression in lung cancer.
Clin Lung Cancer, in press (2016) |
| 2016年12月15日 |
Mori, S., Motoi, N., Ninomiya, H., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Nishio, M., Morikawa, T., Ishikawa, Y. High expression of programmed cell death 1 ligand 1 in lung adenocarcinoma is a poor prognostic factor particularly in smokers and wild-type epidermal growth-factor receptor cases.
Pathol Int, in press (2016) |
| 2016年12月12日 |
Nagasawa, I., Kunimasa, K., Tsukahara, S., Tomida, A. BRAF-mutated cells activate GCN2-mediated integrated stress response as a cytoprotective mechanism in response to vemurafenib.
Biochem Biophys Res Commun, in press (2016) |
| 2016年12月8日 |
Tanaka, M., Homme, M., Yamazaki, Y., Shimizu, R., Takazawa, Y., Nakamura, T. Modeling alveolar soft part sarcoma unveils novel mechanisms of metastasis.
Cancer Res, in press (2016) |
| 2016年10月4日 |
Koido, M., Sakurai, J., Tsukahara, S., Tani, Y., Tomida, A. PMEPA1, a TGF-β- and hypoxia-inducible gene that participates in hypoxic gene expression networks in solid tumors.
Biochem Biophys Res Commun, in press (2016) |
| 2016年8月24日 |
Kurita, D., Takeuchi, K., Kobayashi, S., Hojo, A., Uchino, Y., Sakagami, M., Ohtake, S., Takahashi, H., Miura, K., Iriyama, N., Sugitani, M., Miyoshi, H., Hatta, Y., Ohshima, K., Takei, M. A cyclin D1-negative mantle cell lymphoma with an IGL-CCND2 translocation that relapsed with blastoid morphology and aggressive clinical behavior.
Virchows Archiv, in press (2016) |
| 2016年8月24日 |
Kataoka, K., Shiraishi, Y., Takeda, Y., Sakata, S., Matsumoto, M., Nagano, S., Maeda, T., Nagata, Y., Kitanaka, A., Mizuno, S., Tanaka, H., Chiba, K., Ito, S., Watatani, Y., Kakiuchi, N., Suzuki, H., Yoshizato, T., Yoshida, K., Sanada, M., Itonaga, H., Imaizumi, Y., Totoki, Y., Munakata, W., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Masuda, K., Minato, N., Kashiwase, K., Izutsu, K., Takaori-Kondo, A., Miyazaki, Y., Takahashi, S., Shibata, T., Kawamoto, H., Akatsuka, Y., Shimoda, K., Takeuchi, K., Seya, T., Miyano, S., Ogawa, S. Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.
Nature, 534, 402-406 (2016) |
| 2016年8月9日 |
Hattori, T., Watanabe-Takahashi, M., Shiina, I., Ohashi, Y., Dan, S., Nishikawa, K., Yamori, T., Naito, M. M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin.
Genes to cells : devoted to molecular & cellular mechanisms, 21, 901-906 (2016) |
| 2016年8月9日 |
Narita, K., Matsuhara, K., Itoh, J., Akiyama, Y., Dan, S., Yamori, T., Ito, A., Yoshida, M., Katoh, T. Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors.
Eur J Med Chem, 121, 592-609 (2016) |
| 2016年8月9日 |
Ohashi, Y., Okamura, M., Hirosawa, A., Tamaki, N., Akatsuka, A., Wu, K.M., Choi, H.W., Yoshimatsu, K., Shiina, I., Yamori, T., Dan, S. M-COPA, a golgi disruptor, inhibits cell surface expression of MET protein and exhibits antitumor activity against MET-addicted gastric cancers.
Cancer Res, 76, 3895-3903 (2016) |
| 2016年8月9日 |
Akatsuka, A., Kojima, N., Okamura, M., Dan, S., Yamori, T. A novel thiophene-3-carboxamide analog of annonaceous acetogenin exhibits antitumor activity via inhibition of mitochondrial complex I.
Pharmacology Research & Perspectives, 4, e00246 (2016) |
| 2016年7月21日 |
Gainor, J.F., Dardaei, L., Yoda, K., Friboulet, L., Leshchiner, I., Katayama, R., Dagogo-Jack, I., Gadgeel, S.M., Schultz, K., Singh, M., Chin, E., Parks, M., Lee, D., DiCecca, R.H., Lockerman, E., Huynh, T., Logan, J., Ritterhouse, L.L., Le, L., P., Muniappan, A., Digumarthy, S., Channick, C., Keyes, C., Getz, G., Dias-Santagata, D., Heist, R.S., Lennerz, J., Sequist, L.V., Benes, C.H., Iafrate, A.J., Mino-Kenudson, M., Engelman, J.A., Shaw, A.T. Molecular mechanisms of resistance to first- and second-generation ALK inhibitors in ALK-rearranged lung cancer.
Cancer Discov, in press (2016) |
| 2016年7月13日 |
Abe, Y., Hirota, T. System-level deficiencies in Aurora B control in cancers.
Cell Cycle, in press (2016) |
| 2016年7月13日 |
Nagasaka, K., Hossain, M.J., Roberti, M.J., Ellenberg, J., Hirota, T. Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.
Nat Cell Biol, 18, 692-699 (2016) |
| 2016年7月13日 |
Takahashi, M., Tanaka, K., Wakai, T., Hirota, T. Phosphoproteomic analysis of human mitotic chromosomes identified a chromokinesin KIF4A.
Biomed Res, 37, 161-165 (2016) |
| 2016年7月13日 |
Tanaka, K., Hirota, T. Chromosomal instability: A common feature and a therapeutic target of cancer.
Biochimica et biophysica acta, 1866, 64-75 (2016) |
| 2016年5月24日 |
Kusano, H., Togashi, Y., Akiba, J., Moriya, F., Baba, K., Matsuzaki, N., Yuba, Y., Shiraishi, Y., Kanamaru, H., Kuroda, N., Sakata, S., Takeuchi, K., Yano, H. Two cases of renal cell carcinoma harboring a novel STRN-ALK fusion gene.
Am J Surg Pathol, in press (2016) |
| 2016年5月24日 |
Kataoka, K., Shiraishi, Y., Takeda, Y., Sakata, S., Matsumoto, M., Nagano, S., Maeda, T., Nagata, Y., Kitanaka, A., Mizuno, S., Tanaka, H., Chiba, K., Ito, S., Watatani, Y., Kakiuchi, N., Suzuki, H., Yoshizato, T., Yoshida, K., Sanada, M., Itonaga, H., Imaizumi, Y., Totoki, Y., Munakata, W., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Masuda, K., Minato, N., Kashiwase, K., Izutsu, K., Takaori-Kondo, A., Miyazaki, Y., Takahashi, S., Shibata, T., Kawamoto, H., Akatsuka, Y., Shimoda, K., Takeuchi, K., Seya, T., Miyano, S., Ogawa, S. Aberrant PD-L1 expression via 3’-UTR disruption in multiple cancers.
Nature, in press (2016) |
| 2016年5月20日 |
Toki, H., Minowa, O., Inoue, M., Motegi, H., Karashima, Y., Ikeda, A., Kaneda, H., Sakuraba, Y., Saiki, Y., Wakana, S., Suzuki, H., Gondo, Y., Shiroishi, T., Noda, T. Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Biochem Biophys Res Commun, in press (2016) |
| 2016年5月20日 |
Nakagawa, A., Naito, A.T., Sumida, T., Nomura, S., Shibamoto, M., Higo, T., Okada, K., Sakai, T., Hashimoto, A., Kuramoto, Y., Oka, T., Lee, J.K., Harada, M., Ueda, K., Shiojima, I., Limbourg, F.P., Adams, R.H., Noda, T., Sakata, Y., Akazawa, H., Komuro, I. Activation of endothelial beta-catenin signaling induces heart failure.
Sci Rep, 6, 25009 (2016) |
| 2016年5月17日 |
Suenaga, M., Mashima, T., Kawata, N., Wakatsuki, T., Horiike, Y., Matsusaka, S., Dan, S., Shinozaki, E., Seimiya, H., Mizunuma, N., Yamaguchi, K., Yamaguch, T. Serum VEGF-A and CCL5 levels as candidate biomarkers for efficacy and toxicity of regorafenib in patients with metastatic colorectal cancer.
Oncotarget, in press (2016) |
| 2016年4月18日 |
Abe, Y., Sako, K., Takagaki, K., Hirayama, Y., Uchida, K.S., Herman, J.A., DeLuca, J.G., Hirota, T. HP1-Assisted Aurora B Kinase Activity Prevents Chromosome Segregation Errors.
Dev Cell, 36, 487-497 (2016) |
| 2016年3月18日 |
Nakamura, T., Ma, Y., Iida, K., Ohtake, T., Seimiya, H., Nagasawa, K. Design, synthesis and evaluation of an L-Dopa-derived macrocyclic hexaoxazole (6OTD) as a G-quadruplex-selective ligand.
Heterocycles, in press (2016) |
| 2016年3月18日 |
Mizutani, A., Koinuma, D., Seimiya, H., Miyazono, K. The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma.
Oncogene, in press (2015) |
| 2016年2月9日 |
Kusano, H., Togashi, Y., Akiba, J., Moriya, F., Baba, K., Matsuzaki, N., Yuba, Y., Shiraishi, Y., Kanamaru, H., Kuroda, N., Sakata, S., Takeuchi, K., Yano, H. Two cases of renal cell carcinoma harboring a novel STRN-ALK fusion gene.
Am J Surg Pathol, in press (2016) |
| 2016年1月26日 |
Horiike, A., Takeuchi, K., Uenami, T., Kawano, Y., Tanioto, A., Kaburaki, K., Tambo, Y., Kudo, K., Yanagitani, N., Ohyanagi, F., Motoi, N., Ishikawa, Y., Horai, T., Nishio, M. Sorafenib treatment for patients with RET fusion-positive non-small cell lung cancer.
Lung Cancer, 93, 43-46 (2016) |
| 2016年1月19日 |
Dobashi, A., Tsuyama, N., Asaka, R., Togashi, Y., Ueda, K., Sakata, S., Baba, S., Sakamoto, K., Hatake, K., Takeuchi, K. Frequent BCOR Aberrations in Extranodal NK/T-Cell Lymphoma, Nasal Type.
Genes Chromosomes Cancer, in press (2016) |
| 2016年1月19日 |
Sakamoto, K., Nakasone, H., Togashi, Y., Sakata, S., Tsuyama, N., Baba, S., Dobashi, A., Asaka, R., Tsai, C.C., Chuang, S.S., Izutsu, K., Kanda, Y., Takeuch, K. ALK-positive large B cell lymphoma: identification of EML4-ALK and a review of the literature focusing on the ALK immunohistochemical staining pattern.
Int J Hematol, in press (2016) |
| 2016年1月12日 |
Shimoda, A., Ueda, K., Nishiumi, S., Murata-Kamiya, N., Mukai, S.A., Sawada, S., Azuma, T., Hatakeyama, M., Akiyoshi, K. Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
Sci Rep, 6, 18346 (2016) |
