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最近の論文

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2016年

2016年12月26日
Koido, M., Haga, N., Furuno, A., Tsukahara, S., Sakurai, J., Tani, Y., Sato, S. and Tomida, A.
Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth .
Oncotarget, 8, 11841-854 (2017)
2016年12月19日
Sakha, S., Muramatsu, T., Ueda, K., Inazawa, J.
Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma
Sci Rep, in press (2016)
2016年12月15日
Sakakibara, R., Inamura, K., Tambo, Y., Ninomiya, H., Kitazono, S., Yanagitani, N., Horiike, A., Ohyanagi, F., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Inase, N., Nishio, M., Motoi, N., Ishikawa, Y.
EBUS-TBNA as a promising method for the evaluation of tumor PD-L1 expression in lung cancer.
Clin Lung Cancer, in press (2016)
2016年12月15日
Mori, S., Motoi, N., Ninomiya, H., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Nishio, M., Morikawa, T., Ishikawa, Y.
High expression of programmed cell death 1 ligand 1 in lung adenocarcinoma is a poor prognostic factor particularly in smokers and wild-type epidermal growth-factor receptor cases.
Pathol Int, in press (2016)
2016年12月12日
Nagasawa, I., Kunimasa, K., Tsukahara, S., Tomida, A.
BRAF-mutated cells activate GCN2-mediated integrated stress response as a cytoprotective mechanism in response to vemurafenib.
Biochem Biophys Res Commun, in press (2016)
2016年12月8日
Tanaka, M., Homme, M., Yamazaki, Y., Shimizu, R., Takazawa, Y., Nakamura, T.
Modeling alveolar soft part sarcoma unveils novel mechanisms of metastasis.
Cancer Res, in press (2016)
2016年10月4日
Koido, M., Sakurai, J., Tsukahara, S., Tani, Y., Tomida, A.
PMEPA1, a TGF-β- and hypoxia-inducible gene that participates in hypoxic gene expression networks in solid tumors.
Biochem Biophys Res Commun, in press (2016)
2016年8月24日
Kurita, D., Takeuchi, K., Kobayashi, S., Hojo, A., Uchino, Y., Sakagami, M., Ohtake, S., Takahashi, H., Miura, K., Iriyama, N., Sugitani, M., Miyoshi, H., Hatta, Y., Ohshima, K., Takei, M.
A cyclin D1-negative mantle cell lymphoma with an IGL-CCND2 translocation that relapsed with blastoid morphology and aggressive clinical behavior.
Virchows Archiv, in press (2016)
2016年8月24日
Kataoka, K., Shiraishi, Y., Takeda, Y., Sakata, S., Matsumoto, M., Nagano, S., Maeda, T., Nagata, Y., Kitanaka, A., Mizuno, S., Tanaka, H., Chiba, K., Ito, S., Watatani, Y., Kakiuchi, N., Suzuki, H., Yoshizato, T., Yoshida, K., Sanada, M., Itonaga, H., Imaizumi, Y., Totoki, Y., Munakata, W., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Masuda, K., Minato, N., Kashiwase, K., Izutsu, K., Takaori-Kondo, A., Miyazaki, Y., Takahashi, S., Shibata, T., Kawamoto, H., Akatsuka, Y., Shimoda, K., Takeuchi, K., Seya, T., Miyano, S., Ogawa, S.
Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.
Nature, 534, 402-406 (2016)
2016年8月9日
Hattori, T., Watanabe-Takahashi, M., Shiina, I., Ohashi, Y., Dan, S., Nishikawa, K., Yamori, T., Naito, M.
M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin.
Genes to cells : devoted to molecular & cellular mechanisms, 21, 901-906 (2016)
2016年8月9日
Narita, K., Matsuhara, K., Itoh, J., Akiyama, Y., Dan, S., Yamori, T., Ito, A., Yoshida, M., Katoh, T.
Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors.
Eur J Med Chem, 121, 592-609 (2016)
2016年8月9日
Ohashi, Y., Okamura, M., Hirosawa, A., Tamaki, N., Akatsuka, A., Wu, K.M., Choi, H.W., Yoshimatsu, K., Shiina, I., Yamori, T., Dan, S.
M-COPA, a golgi disruptor, inhibits cell surface expression of MET protein and exhibits antitumor activity against MET-addicted gastric cancers.
Cancer Res, 76, 3895-3903 (2016)
2016年8月9日
Akatsuka, A., Kojima, N., Okamura, M., Dan, S., Yamori, T.
A novel thiophene-3-carboxamide analog of annonaceous acetogenin exhibits antitumor activity via inhibition of mitochondrial complex I.
Pharmacology Research & Perspectives, 4, e00246 (2016)
2016年7月21日
Gainor, J.F., Dardaei, L., Yoda, K., Friboulet, L., Leshchiner, I., Katayama, R., Dagogo-Jack, I., Gadgeel, S.M., Schultz, K., Singh, M., Chin, E., Parks, M., Lee, D., DiCecca, R.H., Lockerman, E., Huynh, T., Logan, J., Ritterhouse, L.L., Le, L., P., Muniappan, A., Digumarthy, S., Channick, C., Keyes, C., Getz, G., Dias-Santagata, D., Heist, R.S., Lennerz, J., Sequist, L.V., Benes, C.H., Iafrate, A.J., Mino-Kenudson, M., Engelman, J.A., Shaw, A.T.
Molecular mechanisms of resistance to first- and second-generation ALK inhibitors in ALK-rearranged lung cancer.
Cancer Discov, in press (2016)
2016年7月13日
Abe, Y., Hirota, T.
System-level deficiencies in Aurora B control in cancers.
Cell Cycle, in press (2016)
2016年7月13日
Nagasaka, K., Hossain, M.J., Roberti, M.J., Ellenberg, J., Hirota, T.
Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.
Nat Cell Biol, 18, 692-699 (2016)
2016年7月13日
Takahashi, M., Tanaka, K., Wakai, T., Hirota, T.
Phosphoproteomic analysis of human mitotic chromosomes identified a chromokinesin KIF4A.
Biomed Res, 37, 161-165 (2016)
2016年7月13日
Tanaka, K., Hirota, T.
Chromosomal instability: A common feature and a therapeutic target of cancer.
Biochimica et biophysica acta, 1866, 64-75 (2016)
2016年5月24日
Kusano, H., Togashi, Y., Akiba, J., Moriya, F., Baba, K., Matsuzaki, N., Yuba, Y., Shiraishi, Y., Kanamaru, H., Kuroda, N., Sakata, S., Takeuchi, K., Yano, H.
Two cases of renal cell carcinoma harboring a novel STRN-ALK fusion gene.
Am J Surg Pathol, in press (2016)
2016年5月24日
Kataoka, K., Shiraishi, Y., Takeda, Y., Sakata, S., Matsumoto, M., Nagano, S., Maeda, T., Nagata, Y., Kitanaka, A., Mizuno, S., Tanaka, H., Chiba, K., Ito, S., Watatani, Y., Kakiuchi, N., Suzuki, H., Yoshizato, T., Yoshida, K., Sanada, M., Itonaga, H., Imaizumi, Y., Totoki, Y., Munakata, W., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Masuda, K., Minato, N., Kashiwase, K., Izutsu, K., Takaori-Kondo, A., Miyazaki, Y., Takahashi, S., Shibata, T., Kawamoto, H., Akatsuka, Y., Shimoda, K., Takeuchi, K., Seya, T., Miyano, S., Ogawa, S.
Aberrant PD-L1 expression via 3’-UTR disruption in multiple cancers.
Nature, in press (2016)
2016年5月20日
Toki, H., Minowa, O., Inoue, M., Motegi, H., Karashima, Y., Ikeda, A., Kaneda, H., Sakuraba, Y., Saiki, Y., Wakana, S., Suzuki, H., Gondo, Y., Shiroishi, T., Noda, T.
Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Biochem Biophys Res Commun, in press (2016)
2016年5月20日
Nakagawa, A., Naito, A.T., Sumida, T., Nomura, S., Shibamoto, M., Higo, T., Okada, K., Sakai, T., Hashimoto, A., Kuramoto, Y., Oka, T., Lee, J.K., Harada, M., Ueda, K., Shiojima, I., Limbourg, F.P., Adams, R.H., Noda, T., Sakata, Y., Akazawa, H., Komuro, I.
Activation of endothelial beta-catenin signaling induces heart failure.
Sci Rep, 6, 25009 (2016)
2016年5月17日
Suenaga, M., Mashima, T., Kawata, N., Wakatsuki, T., Horiike, Y., Matsusaka, S., Dan, S., Shinozaki, E., Seimiya, H., Mizunuma, N., Yamaguchi, K., Yamaguch, T.
Serum VEGF-A and CCL5 levels as candidate biomarkers for efficacy and toxicity of regorafenib in patients with metastatic colorectal cancer.
Oncotarget, in press (2016)
2016年4月18日
Abe, Y., Sako, K., Takagaki, K., Hirayama, Y., Uchida, K.S., Herman, J.A., DeLuca, J.G., Hirota, T.
HP1-Assisted Aurora B Kinase Activity Prevents Chromosome Segregation Errors.
Dev Cell, 36, 487-497 (2016)
2016年3月18日
Nakamura, T., Ma, Y., Iida, K., Ohtake, T., Seimiya, H., Nagasawa, K.
Design, synthesis and evaluation of an L-Dopa-derived macrocyclic hexaoxazole (6OTD) as a G-quadruplex-selective ligand.
Heterocycles, in press (2016)
2016年3月18日
Mizutani, A., Koinuma, D., Seimiya, H., Miyazono, K.
The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma.
Oncogene, in press (2015)
2016年2月9日
Kusano, H., Togashi, Y., Akiba, J., Moriya, F., Baba, K., Matsuzaki, N., Yuba, Y., Shiraishi, Y., Kanamaru, H., Kuroda, N., Sakata, S., Takeuchi, K., Yano, H.
Two cases of renal cell carcinoma harboring a novel STRN-ALK fusion gene.
Am J Surg Pathol, in press (2016)
2016年1月26日
Horiike, A., Takeuchi, K., Uenami, T., Kawano, Y., Tanioto, A., Kaburaki, K., Tambo, Y., Kudo, K., Yanagitani, N., Ohyanagi, F., Motoi, N., Ishikawa, Y., Horai, T., Nishio, M.
Sorafenib treatment for patients with RET fusion-positive non-small cell lung cancer.
Lung Cancer, 93, 43-46 (2016)
2016年1月19日
Dobashi, A., Tsuyama, N., Asaka, R., Togashi, Y., Ueda, K., Sakata, S., Baba, S., Sakamoto, K., Hatake, K., Takeuchi, K.
Frequent BCOR Aberrations in Extranodal NK/T-Cell Lymphoma, Nasal Type.
Genes Chromosomes Cancer, in press (2016)
2016年1月19日
Sakamoto, K., Nakasone, H., Togashi, Y., Sakata, S., Tsuyama, N., Baba, S., Dobashi, A., Asaka, R., Tsai, C.C., Chuang, S.S., Izutsu, K., Kanda, Y., Takeuch, K.
ALK-positive large B cell lymphoma: identification of EML4-ALK and a review of the literature focusing on the ALK immunohistochemical staining pattern.
Int J Hematol, in press (2016)
2016年1月12日
Shimoda, A., Ueda, K., Nishiumi, S., Murata-Kamiya, N., Mukai, S.A., Sawada, S., Azuma, T., Hatakeyama, M., Akiyoshi, K.
Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
Sci Rep, 6, 18346 (2016)

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