Japanese Foundation for Cancer Research
12/20

12Cancer InstituteContributing to the development of innovative cancer treatment through basic researchTo fulfill the mission of the Japanese Foundation for Cancer Research, “promotion of the human welfare by elimination of cancer,? Cancer Institute scientists conduct basic research to discover mechanisms of cancer development and progression and to develop novel therapies. In collaboration with the Cancer Institute Hospital, clinical research scientists discover novel molecular events in human cancer and develop new diagnostic devices. Scientists in all fields share common interests in cancer research and translate their fundamental findings to development of novel therapeutic tools for use in the near future. Our researchers have made epoch-making achieve-ments since the Cancer Institute opened as Japan’s first cancer research institute in 1934. Such work includes cloning of interferon and interleukin-2 genes by Dr. T. Taniguchi and colleagues and identification of the familial adenomatous polyposis gene, APC, by Dr. Y. Nakamura and colleagues. These discoveries gave invaluable contribution to life science and clinical medicine and benefit patients of cancer as well as of non-neoplastic disorders. The Cancer Institute is home to 12 laboratories and 100 faculty and staff members. Today, we are making continuous efforts for fundamental cancer research of the next generation as well as innovative treatment. Part of the studies is achieved in vitro to gain new insights into abnormal cell division and chromosome function in cancer. Studies using animal models provide important breakthroughs on the relationship between cellular senescence and cancer development. The discovery of novel fusion genes in lung cancer will lead to a cancer cure. As an academic and research institution, the Cancer Institute promotes scientic support programs for cancer research in Japan and collaborates with a number of other institutions around the world to enable the sharing of information and use of medical resources.’‘Tetsuo Noda, M.D., Ph.D.Institute DirectorIt is important for cancer control to rapidly feed back the results of basic research. By soundly balancing basic research, translational research, and clinical research, we can promptly provide updated cancer treatment to patients.

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