Sakahara, Mizuho, Takuya Okamoto, Upasna Srivastava, Yasuko Natsume, Hitomi Yamanaka, Yutaka Suzuki, Kazutaka Obama, Satoshi Nagayama, and Ryoji Yao. 2024. “Paneth-like Cells Produced from OLFM4+ Stem Cells Support OLFM4+ Stem Cell Growth in Advanced Colorectal Cancer.” Communications Biology. 7(1): 27.

Nakahara, Ryuichi, Sho Aki, Maki Sugaya, Haruka Hirose, Miki Kato, Keisuke Maeda, Daichi M. Sakamoto, Yasuhiro Kojima, Miyuki Nishida, Ritsuko Ando, Masashi Muramatsu, Melvin Pan, Rika Tsuchida, Yoshihiro Matsumura, Hideyuki Yanai, Hiroshi Takano, Ryoji Yao, Shinsuke Sando, Masabumi Shibuya, Juro Sakai, Tatsuhiko Kodama, Hiroyasu Kidoya, Teppei Shimamura, and Tsuyoshi Osawa. 2023. “Hypoxia Activates SREBP2 through Golgi Disassembly in Bone Marrow‐derived Monocytes for Enhanced Tumor Growth.” The EMBO Journal. 42(22): e114032.

Sasaki, Nobunari, Mizuki Homme, and Shunsuke Kitajima. 2023. “Targeting the Loss of cGAS/STING Signaling in Cancer.” Cancer Science. 114(10): 3806–3815.

Wang, Yuming, Tsunaki Hongu, Tatsunori Nishimura, Yasuto Takeuchi, Hiroshi Takano, Takiko Daikoku, Ryoji Yao, and Noriko Gotoh. 2023. “Mitochondrial One-Carbon Metabolic Enzyme MTHFD2 Facilitates Mammary Gland Development during Pregnancy.” Biochemical and Biophysical Research Communications. 674: 183–189.

Suzuki, Miho M., Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe, Tatsunori Nishimura, Fumiharu Ohka, Ryuta Saito, Shinya Sato, Junya Kobayashi, Ryoji Yao, Kanjiro Miyata, Kazunori Kataoka, Hiroshi I. Suzuki, and Yutaka Kondo. 2023. “TUG1-Mediated R-Loop Resolution at Microsatellite Loci as a Prerequisite for Cancer Cell Proliferation.” Nature Communications. 14(1): 4521.

Fujiwara, Hajime, Satoshi Nagayama, Hiroshi Kawachi, Yuki Shimizu, Ryohei Katayama, Ryoji Yao, Yukiharu Hiyoshi, Toshiki Mukai, Tomohiro Yamaguchi, Toshiya Nagasaki, Takashi Akiyoshi, and Yosuke Fukunaga. 2023. “A Case of Laparoscopically Resected Rectal Neuroendocrine Carcinoma and Its Renal Metastasis with a Potential Sensitivity to Inhibitors of FGFR and the Bcl Family.” Journal of Surgery. 8(7): 1759.

Saeki, Sumito, Kohei Kumegawa, Yoko Takahashi, Liying Yang, Tomo Osako, Mahmut Yasen, Kazutaka Otsuji, Kenichi Miyata, Kaoru Yamakawa, Jun Suzuka, Yuri Sakimoto, Yukinori Ozaki, Toshimi Takano, Takeshi Sano, Tetsuo Noda, Shinji Ohno, Ryoji Yao, Takayuki Ueno, and Reo Maruyama. 2023. “Transcriptomic Intratumor Heterogeneity of Breast Cancer Patient-Derived Organoids May Reflect the Unique Biological Features of the Tumor of Origin.” Breast Cancer Research. 25(1): 21.

Noyes, Christopher, Shunsuke Kitajima, Fengkai Li, Yusuke Suita, Saradha Miriyala, Shakson Isaac, Nagib Ahsan, Erik Knelson, Amir Vajdi, Tetsuo Tani, Tran C. Thai, Derek Xu, Junko Murai, Nikos Tapinos, Chiaki Takahashi, David A. Barbie, and Mamiko Yajima. 2023. “The Germline Factor DDX4 Contributes to the Chemoresistance of Small Cell Lung Cancer Cells.” Communications Biology. 6(1): 65.

Yoshida, Ryohei, Maria Saigi, Tetsuo Tani, Benjamin F. Springer, Hirofumi Shibata, Shunsuke Kitajima, Navin R. Mahadevan, Marco Campisi, William Kim, Yoshihisa Kobayashi, Tran C. Thai, Koji Haratani, Yurie Yamamoto, Shriram K. Sundararaman, Erik H. Knelson, Amir Vajdi, Israel Canadas, Ravindra Uppaluri, Cloud P. Paweletz, Juan J. Miret, Patrick H. Lizotte, Prafulla C. Gokhale, Pasi A. Jänne, and David A. Barbie. 2022. “MET-Induced CD73 Restrains STING-Mediated Immunogenicity of EGFR-Mutant Lung Cancer.” Cancer Research. 82(21): 4079–4092.

Kitajima, Shunsuke, Tetsuo Tani, Benjamin F. Springer, Marco Campisi, Tatsuya Osaki, Koji Haratani, Minyue Chen, Erik H. Knelson, Navin R. Mahadevan, Jessica Ritter, Ryohei Yoshida, Jens Köhler, Atsuko Ogino, Ryu-Suke Nozawa, Shriram K. Sundararaman, Tran C. Thai, Mizuki Homme, Brandon Piel, Sophie Kivlehan, Bonje N. Obua, Connor Purcell, Mamiko Yajima, Thanh U. Barbie, Patrick H. Lizotte, Pasi A. Jänne, Cloud P. Paweletz, Prafulla C. Gokhale, and David A. Barbie. 2022. “MPS1 Inhibition Primes Immunogenicity of KRAS-LKB1 Mutant Lung Cancer.” Cancer Cell. 40(10): 1128-1144.e8.

Okamoto, Takuya, Yasuko Natsume, Motomichi Doi, Hirokazu Nosato, Toshiyuki Iwaki, Hitomi Yamanaka, Mayuko Yamamoto, Hiroshi Kawachi, Tetsuo Noda, Satoshi Nagayama, Hidenori Sakanashi, and Ryoji Yao. 2022. “Integration of Human Inspection and Artificial Intelligence‐based Morphological Typing of Patient‐derived Organoids Reveals Interpatient Heterogeneity of Colorectal Cancer.” Cancer Science. 113(8): 2693–2703.

Asano, Tetsuya, Haruko Nakamura, Yuko Kawamoto, Mikiko Tada, Yayoi Kimura, Hiroshi Takano, Ryoji Yao, Hiroya Saito, Takuya Ikeda, Hiroyasu Komiya, Shun Kubota, Shunta Hashiguchi, Keita Takahashi, Misako Kunii, Kenichi Tanaka, Yoshio Goshima, Fumio Nakamura, Hideyuki Takeuchi, Hiroshi Doi, and Fumiaki Tanaka. 2022. “Inhibition of Crmp1 Phosphorylation at Ser522 Ameliorates Motor Function and Neuronal Pathology in Amyotrophic Lateral Sclerosis Model Mice.” eNeuro. 9(3): ENEURO.0133-22.2022.

Okamoto, Takuya, Yasuko Natsume, Hitomi Yamanaka, Mayuko Fukuda, and Ryoji Yao. 2021. “A Protocol for Efficient CRISPR-Cas9-Mediated Knock-in in Colorectal Cancer Patient-Derived Organoids.” STAR Protocols. 2(4): 100780.

Maru, Yoshiaki, Naotake Tanaka, Yasutoshi Tatsumi, Yuki Nakamura, Ryoji Yao, Tetsuo Noda, Makiko Itami, and Yoshitaka Hippo. 2021. “Probing the Tumorigenic Potential of Genetic Interactions Reconstituted in Murine Fallopian Tube Organoids.” Journal of Pathology. 255(2): 177–189.

Sheng, Jindan, Susumu Kohno, Nobuhiro Okada, Nobuyuki Okahashi, Kana Teranishi, Fumio Matsuda, Hiroshi Shimizu, Paing Linn, Naoko Nagatani, Minako Yamamura, Kenichi Harada, Shin ichi Horike, Hiroshi Inoue, Seiji Yano, Sharad Kumar, Shunsuke Kitajima, Itsuki Ajioka, and Chiaki Takahashi. 2021. “Treatment of Retinoblastoma 1–Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy.” Hepatology. 74(4): 1971–1993.

Okamoto, Takuya, David duVerle, Katsuyuki Yaginuma, Yasuko Natsume, Hitomi Yamanaka, Daisuke Kusama, Mayuko Fukuda, Mayuko Yamamoto, Fanny Perraudeau, Upasna Srivastava, Yukie Kashima, Ayako Suzuki, Yuuta Kuze, Yu Takahashi, Masashi Ueno, Yoshiharu Sakai, Tetsuo Noda, Koji Tsuda, Yutaka Suzuki, Satoshi Nagayama, and Ryoji Yao. 2021. “Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer.” Stem Cell Reports. 16(4): 954-967.

Tani Tetsuo, Shunsuke Kitajima, Ella B. Conway, Erik H. Knelson, David A. Barbie. 2021. “KRAS G12C inhibition and innate immune targeting.” Expert Opinion on Therapeutic Targets. 25(3): 167-174.

Mahadevan, Navin R., Erik H. Knelson, Jacquelyn O. Wolff, Amir Vajdi, Maria Saigi, Marco Campisi, Deli Hong, Tran C. Thai, Brandon Piel, Saemi Han, Bruce B. Reinhold, Jonathan S. Duke-Cohan, Michael J. Poitras, Luke J. Taus, Patrick H. Lizotte, Andrew Portell, Victor Quadros, Alison D. Santucci, Takahiko Murayama, Israel Canadas, Shunsuke Kitajima, Aoi Akitsu, Maya Fridrikh, Hideo Watanabe, Brendan Reardon, Prafulla C. Gokhale, Cloud P. Paweletz, Mark M. Awad, Eliezer M. Van Allen, Ana Lako, Xi-Tao Wang, Benjamin Chen, Fangxin Hong, Lynette M. Sholl, Michael Y. Tolstorukov, Kathleen Pfaff, Pasi A. Janne, Evisa Gjini, Robin Edwards, Scott Rodig, Ellis L. Reinherz, Matthew G. Oser, and David A. Barbie. 2021. “Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.” Cancer Discovery. 11(8): 1952-1969.

Sehgal, Kartik, Andrew Portell, Elena V. Ivanova, Patrick H. Lizotte, Navin R. Mahadevan, Jonathan R. Greene, Amir Vajdi, Carino Gurjao, Tyler Teceno, Luke J. Taus, Tran C. Thai, Shunsuke Kitajima, Derek Liu, Tetsuo Tani, Moataz Noureddine, Christie J. Lau, Paul T. Kirschmeier, David Liu, Marios Giannakis, Russell W. Jenkins, Prafulla C. Gokhale, Silvia Goldoni, Maria Pinzon-Ortiz, William D. Hastings, Peter S. Hammerman, Juan J. Miret, Cloud P. Paweletz, and David A. Barbie. 2021. “Dynamic Single-Cell RNA Sequencing Identifies Immunotherapy Persister Cells Following PD-1 Blockade.” Journal of Clinical Investigation. 131(2): e135038.

Campisi, Marco, Shriram K. Sundararaman, Sarah E. Shelton, Erik H. Knelson, Navin R. Mahadevan, Ryohei Yoshida, Tetsuo Tani, Elena Ivanova, Israel Cañadas, Tatsuya Osaki, Sharon Wei Ling Lee, Tran Thai, Saemi Han, Brandon P. Piel, Sean Gilhooley, Cloud P. Paweletz, Valeria Chiono, Roger D. Kamm, Shunsuke Kitajima, and David A. Barbie. 2020. “Tumor-Derived CGAMP Regulates Activation of the Vasculature.” Frontiers in Immunology 11: 2090.

Osumi, Hiroki, Atsushi Muroi, Mizuho Sakahara, Hiroshi Kawachi, Takuya Okamoto, Yasuko Natsume, Hitomi Yamanaka, Hiroshi Takano, Daisuke Kusama, Eiji Shinozaki, Akira Ooki, Kensei Yamaguchi, Masashi Ueno, Kengo Takeuchi, Tetsuo Noda, Satoshi Nagayama, Naohiko Koshikawa, and Ryoji Yao. 2020. “Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient.” Scientific Reports. 10(1): 17455.

Kitajima, Shunsuke, Fengkai Li, and Chiaki Takahashi. 2020. “Tumor milieu controlled by RB tumor suppressor.” International Journal of Molecular Sciences. 21(7): 2450.

Ito, Chizuru, Hidenori Akutsu, Ryoji Yao, Keiichi Yoshida, Kenji Yamatoya, Tsukasa Makino, Kazuhiro Aoyama, Hiroaki Ishikawa, Koshi Kunimoto, Tetsuo Noda, Masahide Kikkawa, and Kiyotaka Toshimori. 2019. “Odf2 Haploinsufficiency Causes a New Type of Decapitated and Decaudated Spermatozoa, Odf2-DDS, in Mice.” Scientific Reports. 9(1): 14249.

Weng, Jane S., Takanori Nakamura, Hisashi Moriizumi, Hiroshi Takano, Ryoji Yao, and Mutsuhiro Takekawa. 2019. “MCRIP1 Promotes the Expression of Lung-Surfactant Proteins in Mice by Disrupting CtBP-Mediated Epigenetic Gene Silencing.” Communications Biology. 2(1): 227.

Sakahara, Mizuho, Takuya Okamoto, Jun Oyanagi, Hiroshi Takano, Yasuko Natsume, Hitomi Yamanaka, Daisuke Kusama, Mishio Fusejima, Norio Tanaka, Seiich Mori, Hiroshi Kawachi, Masashi Ueno, Yoshiharu Sakai, Tetsuo Noda, Satoshi Nagayama, and Ryoji Yao. 2019. “IFN/STAT Signaling Controls Tumorigenesis and the Drug Response in Colorectal Cancer.” Cancer Science. 110(4): 1293–1305.

Abe, Yuichi, Asa Tada, Junko Isoyama, Satoshi Nagayama, Ryoji Yao, Jun Adachi, and Takeshi Tomonaga. 2018. “Improved Phosphoproteomic Analysis for Phosphosignaling and Active-Kinome Profiling in Matrigel-Embedded Spheroids and Patient-Derived Organoids.” Scientific Reports. 8(1): 11401.

Kawasaki, Natsumi, Kazunobu Isogaya, Shingo Dan, Takao Yamori, Hiroshi Takano, Ryoji Yao, Yasuyuki Morishita, Luna Taguchi, Masato Morikawa, Carl Henrik Heldin, Tetsuo Noda, Shogo Ehata, Kohei Miyazono, and Daizo Koinuma. 2018. “TUFT1 Interacts with RABGAP1 and Regulates MTORC1 Signaling.” Cell Discovery. 4(1): 1–16.

Hayakawa, Yoshihiro, Manabu Kawada, Hiroyoshi Nishikawa, Takahiro Ochiya, Hideyuki Saya, Hiroyuki Seimiya, Ryoji Yao, Masahiro Hayashi, Chieko Kai, Akira Matsuda, Tomoki Naoe, Atsushi Ohtsu, Taku Okazaki, Hideo Saji, Masataka Sata, Haruhiko Sugimura, Yuichi Sugiyama, Masakazu Toi, and Tatsuro Irimura. 2016. “Report on the Use of Non-Clinical Studies in the Regulatory Evaluation of Oncology Drugs.” Cancer Science. 107(2): 189–202.

Yao, Ryoji, Seiichi Mori, and Tetsuo Noda. 2015. “JCA-AACR Joint Symposia in the 73rd Annual Meeting of the Japanese Cancer Association, Yokohama, 25-26 September 2014.” Cancer Science. 106(4): 475–479.

Toki, Hideaki, Maki Inoue, Osamu Minowa, Hiromi Motegi, Yuriko Saiki, Shigeharu Wakana, Hiroshi Masuya, Yoichi Gondo, Toshihiko Shiroishi, Ryoji Yao, and Tetsuo Noda. 2014. “Novel Retinoblastoma Mutation Abrogating the Interaction to E2F2/3, but Not E2F1, Led to Selective Suppression of Thyroid Tumors.” Cancer Science. 105(10): 1360–1368.

Toki, Hideaki, Maki Inoue, Hiromi Motegi, Osamu Minowa, Hiroaki Kanda, Noriko Yamamoto, Ami Ikeda, Yuko Karashima, Junko Matsui, Hideki Kaneda, Ikuo Miura, Tomohiro Suzuki, Shigeharu Wakana, Hiroshi Masuya, Yoichi Gondo, Toshihiko Shiroishi, Tetsu Akiyama, Ryoji Yao, and Tetsuo Noda. 2013. “Novel Mouse Model for Gardner Syndrome Generated by a Large-Scale N-Ethyl-N-Nitrosourea Mutagenesis Program.” Cancer Science. 104(7): 937–944.

Ito, Chizuru, Kenji Yamatoya, Keiichi Yoshida, Koichi Kyono, Ryoji Yao, Tetsuo Noda, and Kiyotaka Toshimori. 2010. “Appearance of an Oocyte Activation-Related Substance during Spermatogenesis in Mice and Humans.” Human Reproduction. 25(11): 2734–2744.

Ito, Chizuru, Hidenori Akutsu, Ryoji Yao, Koichi Kyono, Fumie Suzuki-Toyota, Yoshiro Toyama, Mamiko Maekawa, Tetsuo Noda, and Kiyotaka Toshimori. 2009. “Oocyte Activation Ability Correlates with Head Flatness and Presence of Perinuclear Theca Substance in Human and Mouse Sperm.” Human Reproduction. 24(10): 2588–2595.

Yajima, Ibuki, Tatsuhiko Tanizawa, Noriyuki Yamamoto, Toyoshi Fukuda, Tokio Higashi, Sakuyoshi Tabata, Ryoji Yao, Hideyuki Yamato, and Hisashi Murayama. 2009. “A Case Report of a Bone Histomorphometrical Analysis after a Total Parathyroidectomy.” Therapeutic Apheresis and Dialysis. 13(1): 83–87.

Suzuki-Toyota, Fumie, Chizuru Ito, Yoshiro Toyama, Mamiko Maekawa, Ryoji Yao, Tetsuo Noda, Hiroshi Iida, and Kiyotaka Toshimori. 2007. “Factors Maintaining Normal Sperm Tail Structure During Epididymal Maturation Studied in Gopc−/− Mice1.” Biology of Reproduction. 77(1): 71–82.

Yao, Ryoji, Yasuko Natsume, and Tetsuo Noda. 2007. “TACC3 Is Required for the Proper Mitosis of Sclerotome Mesenchymal Cells during Formation of the Axial Skeleton.” Cancer Science. 98(4): 555–562.

Kumada, Kazuki, Ryoji Yao, Tokuichi Kawaguchi, Mika Karasawa, Yutaka Hoshikawa, Koji Ichikawa, Yoshinobu Sugitani, Issei Imoto, Johji Inazawa, Minoru Sugawara, Mitsuhiro Yanagida, and Tetsuo Noda. 2006. “The Selective Continued Linkage of Centromeres from Mitosis to Interphase in the Absence of Mammalian Separase.” Journal of Cell Biology. 172(6): 835–846.

Yokokura, Shunji, Yuko Wada, Shigeyasu Nakai, Hajime Sato, Ryoji Yao, Hitomi Yamanaka, Sioko Ito, Yoshiko Sagara, Mayumi Takahashi, Yukie Nakamura, Makoto Tamai, and Tetsuo Noda. 2005. “Targeted Disruption of FSCN2 Gene Induces Retinopathy in Mice.” Investigative Ophthalmology and Visual Science. 46(8): 2905–2915.

Suzuki-Toyota, Fumie, Chizuru Ito, Yoshiro Toyama, Mamiko Maekawa, Ryoji Yao, Tetsuo Noda, and Kiyotaka Toshimori. 2004. “The Coiled Tail of the Round-Headed Spermatozoa Appears during Epididymal Passage in GOPC-Deficient Mice.” Archives of Histology and Cytology. 67(4): 361–371.

Yao, Ryoji, Yasuko Natsume, and Tetsuo Noda. 2004. “MAGI-3 Is Involved in the Regulation of the JNK Signaling Pathway as a Scaffold Protein for Frizzled and Ltap.” Oncogene. 23(36): 6023–6030.

Nakamura, Takahisa, Ryoji Yao, Takehiko Ogawa, Toru Suzuki, Chizuru Ito, Naoki Tsunekawa, Kimiko Inoue, Rieko Ajima, Takashi Miyasaka, Yutaka Yoshida, Atsuo Ogura, Kiyotaka Toshimori, Toshiaki Noce, Tadashi Yamamoto, and Tetsuo Noda. 2004. “Oligo-Astheno-Teratozoospermia in Mice Lacking Cnot7, a Regulator of Retinoid X Receptor Beta.” Nature Genetics. 36(5): 528–533.

Ito, Chizuru, Fumie Suzuki-Toyota, Mamiko Maekawa, Yoshiro Toyama, Ryoji Yao, Tetsuo Noda, and Kiyotaka Toshimori. 2004. “Failure to Assemble the Peri-Nuclear Structures in GOPC Deficient Spermatids as Found in Round-Headed Spermatozoa.” Archives of Histology and Cytology. 67(4): 349–360.

Sasaki, Toru, Hiroyuki Suzuki, Ken Yagi, Masao Furuhashi, Ryoji Yao, Shinji Susa, Tetsuo Noda, Yoichi Arai, Kohei Miyazono, and Mitsuyasu Kato. 2003. “Lymphoid Enhancer Factor 1 Makes Cells Resistant to Transforming Growth Factor β-Induced Repression of c-Myc.” Cancer Research. 63(4): 801–806.

Yao, Ryoji, Chizuru Ito, Yasuko Natsume, Yoshinobu Sugitani, Hitomi Yamanaka, Shoji Kuretake, Kaoru Yanagida, Akira Sato, Kiyotaka Toshimori, and Tetsuo Noda. 2002. “Lack of Acrosome Formation in Mice Lacking a Golgi Protein, GOPC.” Proceedings of the National Academy of Sciences of the United States of America. 99(17): 11211–11216.