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Human Pu-seq data
Koyanagi et al Nat Commun 2022
Data available:
  • Genomic usage profiles of Polε and Polα, which engage in leading- and lagging-strand synthesis, respectively.
  • Initiation index (positive values: replication initiation efficiency; negative values: replication fork termination efficiency) calculated from polymerase profiles.
  • Replication Initiation Zones (IZ) defined from the Initiation index.
Bainbridge et al 2026
Data available:
  • Genomic usage profiles of Polη in HCT116 cells.
  • Genomic usage profiles of Polη in PCNA-K164R, POLH-PIP3, POLD3-PIP, POLK-deficient, and RAD18-overexpression cells.
  • Genomic usage profiles of Polη in hTERT-RPE1 cells.
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