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Launching chromosome condensation as cells enter mitosis

In eukaryotes, DNA replication during S phase and subsequent chromosome segregation during M phase are the basis for the transmission of their genomes from one generation to the next. The fidelity of this process depends on the ability of chromatin, which in human cells can reach several centimeters in length, to assemble into rod-shaped chromosomes in mitosis, whose sizes are only a few microns long. How do cells achieve this remarkable feat? More

Laboratories

Physics

Temporarily closed.

Biochemistry

Temporarily closed.

Chemotherapy

Developing safe and effective anti-cancer drugs and treatments

Pathology Project for Molecular Targets

Our aim is to create a novel field of pathology for patients, therapy-oriented pathology.

Cancer Systems Biology

Our goal is to establish novel cancer therapeutic paradigm from robustness-based approach.(

Cancer Genomics

Our aims are to establish personalized medicine and novel bioinformatics methodology.

Protein Engineering

Our aim is to develop cancer diagnosis methods through the use of artificial proteins.

Genetic Diagnosis

We aim to elucidate the mechanisms of breast oncogenesis and establish genetic diagnosis.

Carcinogenesis

We will explore novel approach for cancer treatment by clarifying carcinogenic mechanism.

Cancer Biology

We aim to understand cellular senescence and to elucidate how it is perturbed in cancer.

Experimental Pathology

We aim to elucidate the mechanisms underlying chromosomal instability in cancer cells.

Cell Biology

We investigate carcinogenesis in vivo to develop novel strategies for cancer prevention and treatment.

Pathology

Our activities involve research on cancer prevention and diagnosis for JFCR Hospital.

Recent Publications

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