![]()

![]()
In eukaryotes, DNA replication during S phase and subsequent chromosome segregation during M phase are the basis for the transmission of their genomes from one generation to the next. The fidelity of this process depends on the ability of chromatin, which in human cells can reach several centimeters in length, to assemble into rod-shaped chromosomes in mitosis, whose sizes are only a few microns long. How do cells achieve this remarkable feat? More
![]()
![]()
We investigate carcinogenesis in vivo to develop novel strategies for cancer prevention and treatment.


