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2018-04-02
Contents
Original articles
2018｜2017｜2016｜2015｜2014｜2013｜2012｜2011｜2010｜2009｜2008｜2007｜2006
2018年
- Krishnan H, Rayes J, Miyashita T, Ishii G, Retzbach EP, Sheehan SA, Takemoto A, Chang YW, Yoneda K, Asai J, Jensen L, Chalise L, Natsume A, Goldberg GS
- Podoplanin - an emerging cancer biomarker and therapeutic target. Cancer Science in press (2018)
- Katayama R.
- Drug resistance in anaplastic lymphoma kinase-rearranged lung cancer. Cancer Science. 109:572-580. (2018)
- Ariyasu R, Nishikawa S, Uchibori K, Oh-Hara T, Yoshizawa T, Dotsu Y, Koyama J, Saiki M, Sonoda T, Kitazono S, Yanagitani N, Horiike A, Inase N, Kasahara K, *Nishio M, *Katayama R
- High ratio of T790M to EGFR activating mutations correlate with the osimertinib response in non-small-cell lung cancer. Lung Cancer, 117: 1-6 (2018)
2017
- Ohashi Y, Okamura M, Katayama R, Fang S, Tsutsui S, Akatsuka A, Shan M, Choi HW, Fujita N, Yoshimatsu K, Shiina I, Yamori T, Dan S.
- Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors. Oncotarget, 9:1641-1655. (2017)
- Fuse, M.J., Okada, K., Oh-hara, T., Ogura, H., Fujita, N. and Katayama, R.
- Mechanisms of resistance to NTRK inhibitors and therapeutic strategies in NTRK1-rearranged cancers. Mol. Cancer Ther., 16:2130-2143. (2017)
- Takemoto, A., Miyata, K. and Fujita, N.
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Platelet-activating factor podoplanin: from discovery to drug development.
Cancer and metastasis reviews, 36, 225-234 (2017) - Ogura, H., Nagatake-Kobayashi, Y., Adachi, J., Tomonaga, T., Fujita, N. and Katayama, R.
-
TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
Sci. Rep., 7, 5519 (2017) - R. Katayama.
- Therapeutic strategies and mechanisms of drug resistance in Anaplastic Lymphoma Kinase (ALK)-rearranged lung cancer. Pharmacol. Ther., 117, 1-8 (2017)
- Miyata, K., Takemoto, A., Okumura, S., Nishio, M. and Fujita, N.
-
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation.
Sci. Rep., 7, 4059 (2017) - Uchibori, K., Inase, N., Araki, M., Kamada, M., Sato, S., Okuno, Y., Fujita, N., Katayama, R.
- Brigatinib overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer. Nature Commun, 8: 14768 (2017).
- Takemoto, A., Okitaka, M., Takagi, S., Takami, M., Sato, S., Nishio, M., Okumura, S., Fujita, N.
- A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis. Sci Reports, 7: 42186 (2017).
- Takeuchi, S., Fukuda, K., Yamada, T., Arai, S., Takagi, S., Ishii, G., Ochiai, A., Iwakiri, S., Itoi, K., Uehara,H., Nishihara, H., Fujita, N., Yano, S.
- Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and contact inhibition. Cancer Sci, In press (2017).
- Tanaka, N., Mashima, T., Mizutani, A., Sato, A., Aoyama, A., Gong, B., Yoshida, H., Muramatsu,Y., Nakata, K., Matsuura, M., Katayama, R., Nagayama, S., Fujita, N., Sugimoto, Y., Seimiya H.
- APC mutations as a predictive biomarker for sensitivity to tankyrase inhibitors in colorectal cancer. Mol Cancer Ther, In press (2017).
- R. Katayama.
- Therapeutic strategies and mechanisms of drug resistance in Anaplastic Lymphoma Kinase (ALK)-rearranged lung cancer.
Pharmacol. Ther., in press (2017)
2016
- Katayama, R., Sakashita, T., Yanagitani, N., Ninomiya, H., Horiike, A., Friboulet, L., Gainor, J. F., Motoi, N., Dobashi, A., Sakata, S., Tambo, Y., Kitazono, S., Sato, S., Koike, S., Iafrate, A. J., Mino-Kenudson, M., Ishikawa, Y., Shaw, A. T., Engleman, J. A., Takeuchi, K., Nishio, M., Fujita, N.
- P-glycoprotein mediates ceritinib resistance in anaplastic lymphoma kinase-rearranged non-small cell lung cancer. EBioMedicine, 3, 54-66 (2016)
- Shaw, A. T., Friboulet, L., Leshchiner, I., Gainor, J. F., Berggvist, S., Brooun, A., Burke, B. J., Deng, Y. L., Liu, W., Dardaei, L., Frias, R. L., Schultz, K. R., Logan, J., James, L. P., Smeal, T., Timofeevski, S., Katayama, R., Iafrate, A. J., Le, L., McTigue, M., Getz, G., Johnson, T. W., Engelman, J. A.
- Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F. N Engl J Med, 374: 54-61 (2016)
- Sekiguchi, T., Takemoto, A., Takagi, S., Takatori, K., Sato, S., Takami, M., Fujita, N.
- Targeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasis. Oncotarget, 7, 3934-3946 (2016)
- J. F. Gainor, L. Dardaei, S. Yoda, L. Friboulet, I. Leshchiner, R. Katayama, I. Dagogo-Jack, S. Gadgeel, K. Schultz, M. Singh, E. Chin, M. Parks, D. Lee, R. H. DiCecca, E. Lockerman, T. Huynh, J. Logan, L. L. Ritterhouse, L. P. Le, A. Muniappan, S. Digumarthy, C. Channick, C. Keyes, G. Getz, D. Dias-Santagata, R. S. Heist, J. Lennerz, L. V. Sequist, C. H. Benes, A. J. Iafrate, M. Mino-Kenudson, J. A. Engelman and A. T. Shaw.
- Molecular mechanisms of resistance to first- and second-generation ALK inhibitors in ALK-rearranged lung cancer.
Cancer Discov., 6, 1118-1133 (2016)
2015
- Katayama, R., Kobayashi, Y., Friboulet, L., Lockerman, E.L., Koike, S., Shaw, A.T., Engelman, J.A., Fujita, N.
- Cabozantinib overcomes crizotinib resistance in ROS1 fusion positive
cancer.
Clin Cancer Res, 21, 166-174 (2015) - Hu, D., Gur, M., Zhou, Z., Gamper, A., Hung, M. C., Fujita, N., Lan, L., Bahar, I., Wan, Y.
- Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.
Nat Commun, 6, 8419 (2015) - Niederst, M. J., Sequist, L. V., Poirier, J. T., Mermel, C. H., Lockerman, E. L., Garcia, A. R., Katayama, R., Costa, C., Ross, K. N., Moran, T., Howe, E., Fulton, L. E., Mulvey, H. E., Bernardo, L. A., Mohamoud, F., Miyoshi, N., VanderLaan, P. A., Costa, D. B., Janne, P. A., Borger, D. R., Ramaswamy, S., Shioda, T., Iafrate, A. J., Getz, G., Rudin, C. M., Mino-Kenudson, M., Engelman, J. A.
- RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer. Nat Commun, 6, 6377 (2015)
- Yamada, T., Amann, J. M., Fukuda, K., Takeuchi, S., Fujita, N., Uehara, H., Iwakiri, S., Itoi, K., Shilo, K., Yano, S., Carbone, D. P.
- Akt kinase-interacting protein Aki1 signals through CREB to drive diffuse malignant mesothelioma. Cancer Res, 75, 4188-4197 (2015)
- Zou, H. Y., Friboulet, L., Kodack, D. P., Engstrom, L. D., Li, Q., West, M., Tang, R. W., Wang, H., Tsaparikos, K., Wang, J., Timofeevski, S., Katayama, R., Dinh, D. M., Lam, H., Lam, J. L., Yamazaki, S., Hu, W., Patel, B., Bezwada, D., Frias, R. L., Lifshits, E., Mahmood, S., Gainor, J. F., Affolter, T., Lappin, P. B., Gukasyan, H., Lee, N., Deng, S., Jain, R. K., Johnson, T. W., Shaw, A. T., Fantin, V. R., Smeal, T.
- PF-06463922, an ALK/ROS1 Inhibitor, Overcomes Resistance to First and Second Generation ALK Inhibitors in Preclinical Models. Cancer Cell, 28, 70-81 (2015)
2014
- Aoyama, A., Katayama, R., Oh-hara, T., Sato, S., Okuno, Y., Fujita, N.
- Tivantinib (ARQ 197) exhibits antitumor activity by directly interacting
with tubulin and overcomes ABC transporter-mediated drug resistance.
Mol Cancer Ther, 13, 2978-2990 (2014) - Chowdhury, M.M., Danoy, M., Rahman, F., Shinohara, M., Kaneda, S., Shiba, K., Fujita, N., Fujii, T., Sakai, Y.
- Adhesion of pancreatic cancer cells in a liver-microvasculature mimicking coculture correlates with their propensity to form liver-specific metastasis in vivo.
Biomed Res Int, 2014, 241571 (2014) - Friboulet, L., Li, N., Katayama, R., Lee, C.C., Gainor, J.F., Crystal, A.S., Michellys, P.Y., Awad, M.M., Yanagitani, N., Kim, S., Pferdekamper, A.C., Li, J., Kasibhatla, S., Sun, F., Sun, X., Hua, S., McNamara, P., Mahmood, S., Lockerman, E.L., Fujita, N., Nishio, M., Harris, J.L., Shaw, A.T., Engelman, J.A.
- The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer.
Cancer Discov, 4, 662-673 (2014) - Katayama, R., Friboulet, L., Koike, S., Lockerman, E.L., Khan, T.M., Gainor, J.F., Iafrate, A.J., Takeuchi, K., Taiji, M., Okuno, Y., Fujita, N., Engelman, J.A., Shaw, A.T.
- Two novel ALK mutations mediate acquired resistance to the next-generation AKL inhibitor alectinib.
Clin Cancer Res, 20, 5686-5696 (2014) - Miyata, K., Takagi, S., Sato, S., Morioka, H., Shiba, K., Minamisawa, T., Takami, M., Fujita, N.
- Suppression of Aggrus/podoplanin-induced platelet aggregation and pulmonary metastasis by a single-chain antibody variable region fragment.
Cancer Med, 3, 1595-1604 (2014) - Ohtsubo, K., Yamada, T., Zhao, L., Jin, T.F., Takeuchi, S., Mouri, H., Yamashita, K., Yasumoto, K., Fujita, N., Kitagawa, H., Ohta, T., Ikeda, H., Yano, S.
- Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3K/PDK1/Akt pathway, in pancreatic cancer.
Pancreas, 43, 1093-1100 (2014) - Pond, A.L., Nedele, C., Wang, W.H., Wang, X., Walther, C., Jaeger, C., Bradley, K.S., Du, H., Fujita, N., Hockerman, G.H., Hannon, K.M.
- The mERG1a channel modulates skeletal muscle MuRF1, but not MAFbx, expression.
Muscle Nerve, 49, 378-388 (2014) - Takagi, S., Oh-Hara, T., Sato, S., Gong, B., Takami, M., Fujita, N.
- Expression of Aggrus/podoplanin in bladder cancer and its role in pulmonary
metastasis.
Int J Cancer, 134, 2605-2614 (2014) - Takagi, S., Takemoto, A., Takami, M., Oh-Hara, T., Fujita, N.
- Platelets promote osteosarcoma cell growth through activation of the platelet-derived growth factor receptor-Akt signaling axis.
Cancer Sci, 105, 983-988 (2014)
2013
- Katayama, R., Aoyama, A., Yamori, T., Qi, J., Oh-Hara, T., Song, Y., Engelman, J.A., Fujita, N.
- Cytotoxic activity of Tivanitib (ARQ 197) is not due solely to c-MET inhibition.
Cancer Res, 73, 3087-3096 (2013) - Takagi, S., Sato, S., Oh-Hara, T., Takagi, M., Koike, S., Mishima, Y., Hatake, K., Fujita, N.
- Platelets promote tumor growth and metastasis via direct interaction between Aggrus/Podoplanin and CLEC-2.
PLoS One, 8, e73609 (2013) - Yamada, T., Takeuchi, S., Fujita, N., Nakamura, A., Wang, W., Li, Q., Oda, M., Mitsudomi, T., Yatabe, Y., Sekido, Y., Yoshida, J., Higashiyama, M., Noguchi, M., Uehara, H., Nishioka, Y., Sone, S., Yano, S.
- Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations.
Oncogene, 32, 4427-4435 (2013)
2012
- Fujita, N., Takagi, S.
- The impact of Aggrus/podoplanin on platelet aggregation and tumor metastasis.
J Biochem, 152, 407-413 (2012) - Hahne, J.C., Honig, A., Meyer, S.R., Gambaryan, S., Walter, U., Wischhusen, J., Haussler, S.F., Segerer, S.E., Fujita, N., Dietl, J., Engel, J.B.
- Downregulation of AKT reverses platinum resistance of human ovarian cancers in vitro.
Oncol Rep, 28, 2023-2028 (2012) - Mohanty, A.R., Kan, Q., Srivastava, S., Uranbileg, B., Arakawa-Takeuchi, S., Fujita, N., Okayama, H.
- Successive phosphorylation of p27Kip1 protein at serine-10 and C-terminus crucially controls its cotency to inactivate cdk2.
J Biol Chem, 287, 21757-21764 (2012)
2011
- Ehata, S., Johansson, E., Katayama, R., Koike, S., Watanabe, A., Hoshino, Y., Katsuno, Y., Komuro, A., Koinuma, D., Kano, M.R., Yashiro, M., Hirakawa, K., Aburatani, H., Fujita, N., Miyazono, K.
- Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells.
Oncogene, 30, 1693-1705 (2011) - Konishi, S., Yasuchika, K., Ishii, T., Fukumitsu, K., Kamo, N., Fujita, N., Ikai, I., Uemoto, S.
- A transmembrane glycoprotein, gp38, is a novel marker for immature hepatic progenitor cells in fetal mouse livers.
In Vitro Cell Dev Biol Anim, 47, 45-53 (2011) - Morishita, D., Takami, M., Yoshikawa, S., Katayama, R., Sato, S., Kukimoto-Niino, M., Umehara, T., Shirouzu, M., Sekimizu, K., Yokoyama, S., Fujita, N.
- Cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
J Biol Chem, 286, 2681-2688 (2011) - Nakazawa, Y., Arai, H., Fujita, N.
- The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis.
Cancer Res, 71, 1146-1155 (2011) - Nakazawa, Y., Takagi, S., Sato, S., Oh-Hara, T., Koike, S., Takami, M., Arai, H., Fujita, N.
- Prevention of hematogenous metastasis by neutralizing mice and its chimeric anti-Aggrus/podoplanin antibodies.
Cancer Sci, 102, 2051-2057 (2011)
2010
- Katayama, R., Ishioka, T., Takada, S., Takada, R., Fujita, N., Tsuruo, T., Naito, M.
- Modulation of Wnt signaling by the nuclear localization of cellular FLIP-L.
J Cell Sci, 123, 23-28 (2010) - Misawa, A., Katayama, R., Koike, S., Tomida, A., Watanabe, T., Fujita, N.
- AP-1-Dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells.
Oncol Res, 19, 23-33 (2010) - Nakamura, A., Naito, M., Arai, H., Fujita, N.
- Mitotic phosphorylation of Aki1 at Ser208 by cyclin B1-Cdk1 complex.
Biochem Biophys Res Commun, 393, 872-876 (2010) - Péterfy, M., Harris, T.E., Fujita, N., Reue, K.
- Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
J Biol Chem, 285, 3857-3864 (2010)
2009
- Demers, M.J., Thibodeau, S., Noel, D., Fujita, N., Tsuruo, T., Gauthier, R., Arguin, M., Vachon, P.H.
- Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1.
J Cell Biochem, 107, 639-654 (2009) - Katayama, R., Koike, S., Sato, S., Sugimoto, Y., Tsuruo, T., Fujita, N.
- Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.
Cancer Sci, 100, 2060-2068 (2009) - Nakamura, A., Arai, H., Fujita, N.
- Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement.
J Cell Biol, 187, 607-614 (2009) - Tanaka, H., Hoshikawa, Y., Oh-hara, T., Koike, S., Naito, M., Noda, T., Arai, H., Tsuruo, T., Fujita, N.
- PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-κB activation.
Mol Cancer Res, 7, 557-569 (2009)
2008
- Bouchard, V., Harnois, C., Demers, M.J., Thibodeau, S., Laquerre, V., Gauthier, R., Vezina, A., Noel, D., Fujita, N., Tsuruo, T., Arguin, M., Vachon, P.H.
- β1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms.
Apoptosis, 13, 531-542 (2008) - Katayama, K., Nakamura, A., Sugimoto, Y., Tsuruo, T., Fujita, N.
- FOXO transcription factor-dependent p15INK4b and p19INK4d expression.
Oncogene, 27, 1677-1686 (2008) - Kurata, A., Katayama, R., Watanabe, T., Tsuruo, T., Fujita, N.
- TUSC4/NPRL2, a novel PDK1-interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling.
Cancer Sci, 99, 1827-1834 (2008) - Morishita, D., Katayama, R., Sekimizu, K., Tsuruo, T., Fujita, N.
- Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.
Cancer Res, 68, 5076-5085 (2008) - Nakamura, A., Naito, M., Tsuruo, T., Fujita, N.
- Freud-1/Aki1, a novel PDK1-interacting protein, functions as a scaffold to activate the PDK1/Akt pathway in epidermal growth factor signaling.
Mol Cell Biol, 28, 5996-6009 (2008) - Nakasaki, T., Tanaka, T., Okudaira, S., Hirosawa, M., Umemoto, E., Otani, K., Jin, S., Bai, Z., Hayasaka, H., Fukui, Y., Aozasa, K., Fujita, N., Tsuruo, T., Ozono, K., Aoki, J., Miyasaka, M.
- Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions.
Am J Pathol, 173, 1566-1576 (2008) - Nakazawa, Y., Sato, S., Naito, M., Kato, Y., Mishima, K., Arai, H., Tsuruo, T., Fujita, N.
- Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis.
Blood, 112, 1730-1739 (2008)
2007
- Bouchard, V., Demers, M.J., Thibodeau, S., Laquerre, V., Fujita, N., Tsuruo, T., Beaulieu, J.F., Gauthier, R., Vezina, A., Villeneuve, L., Vachon, P.H.
- Fak/Src signaling in human intestinal epithelial cell survival and anoikis: differentiation state-specific uncoupling with the PI3-K/Akt-1 and MEK/Erk pathways.
J Cell Physiol, 212, 717-728 (2007) - Kamo, N., Yasuchika, K., Fujii, H., Hoppo, T., Machimoto, T., Ishii, T., Fujita, N., Tsuruo, T., Yamashita, J.K., Kubo, H., Ikai, I.
- Two populations of Thy1-positive mesenchymal cells regulate in vitro maturation of hepatic progenitor cells.
Am J Physiol Gastrointest Liver Physiol, 292, G526-534 (2007) - Kunita, A., Kashima, T.G., Morishita, Y., Fukayama, M., Kato, Y., Tsuruo, T., Fujita, N.
- The platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasis.
Am J Pathol, 170, 1337-1347 (2007) - Rosner, M., Freilinger, A., Hanneder, M., Fujita, N., Lubec, G., Tsuruo, T., Hengstschläger, M.
- p27Kip1 localization depends on the tumor suppressor protein tuberin.
Hum Mol Genet, 16, 1541-1556 (2007) - Tokuda, E., Fujita, N., Oh-hara, T., Sato, S., Kurata, A., Katayama, R., Itoh, T., Takenawa, T., Miyazono, K., Tsuruo, T.
- Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.
Cancer Res, 67, 9666-9676 (2007)
2006
- Dai, J., Bai, J., Hasegawa, T., Nishizawa, S., Sakai, J., Oka, S., Kiuchi, M., Hirose, K., Tomida, A., Tsuruo, T., Li, M., Ando, M.
- A new taxoid from a callus culture of Taxus cuspidata as an MDR reversal agent.
Chem Pharm Bull (Tokyo), 54, 306-309 (2006) - Kono, T., Kubo, H., Shimazu, C., Ueda, Y., Takahashi, M., Yanagi, K., Fujita, N., Tsuruo, T., Wada, H., Yamashita, J.K.
- Differentiation of lymphatic endothelial cells from embryonic stem cells on OP9 stromal cells.
Arterioscler Thromb Vasc Biol, 26, 2070-2076 (2006) - Li, N., Wu, J.L., Hasegawa, T., Sakai, J., Wang, L.Y., Kakuta, S., Furuya, Y., Tomida, A., Tsuruo, T., Ando, M.
- Bioactive dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii.
J Nat Prod, 69, 234-239 (2006) - Mishima, K., Kato, Y., Kaneko, M.K., Nakazawa, Y., Kunita, A., Fujita, N., Tsuruo, T., Nishikawa, R., Hirose, T., Matsutani, M.
- Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma.
Acta Neuropathol, 111, 563-568 (2006) - Tahara, H., Shin-Ya, K., Seimiya, H., Yamada, H., Tsuruo, T., Ide, T.
- G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
Oncogene, 25, 1955-1966 (2006) - Wu, J.L., Li, N., Hasegawa, T., Sakai, J., Mitsui, T., Ogura, H., Kataoka, T., Oka, S., Kiuchi, M., Tomida, A., Tsuruo, T., Li, M., Tang, W., Ando, M.
- Bioactive secolignans from Peperomia dindygulensis.
J Nat Prod, 69, 790-794 (2006)
