Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Yoshitake, H., Negoto, T., Moritsubo, M., Furuta, T., Jo, M., Hirota, T., Sakata, K., Nakamura, H. and Morioka, M.
Chromosomal instability is associated with paradoxical cGAS upregulation and impaired STING signaling shaping the immune microenvironment in glioblastoma.
Neurooncol. Adv., vdag179 (2026)
Hara, T., Meng, S., Konno, M., Nishida, N., Koseki, J., Meguro, K., Kawano, Y., Morie, T., Dan, S., Satoh, T., Akai, S., Tsujikawa, K., Eguchi, H., Mori, M., Miura, Y., Nishiyama, N. and Ishii, H.
Identification of novel small-molecule inhibitors targeting KDM5B and evaluation of their antitumour effects.
Cancer Med., 15, e72058 (2026)
Ozaki, H., Sasaki, N. and Kitajima, S.
An aminoacyl-tRNA synthetase governs dsRNA-mediated trade-off between longevity and innate immunity.
Mol. Cell, 86, 2237-2239 (2026)
Kamakura, N., Jo, M., Takahashi, M. and Hirota, T.
Targeting cell cycle vulnerabilities in cancers: Emerging strategies for therapeutic development.
Cancer Sci., in press (2026)
Tanaka, T., Fujitani, M., Taoka, M., Shimomura, I., Okawa, S., Mori, S., Kuribayashi, T., Nishimura, J., Nishimura, T., Morita, A., Hara, N., Ninomiya, K., Makimoto, G., Higo, H., Rai, K., Ichihara, E., Tomida, S., Hotta, K., Togashi, Y., Maeda, Y., Kiura, K., Katayama, R. and Ohashi, K.
Afatinib overcomes osimertinib resistance via Egfr v804f mutation in a syngeneic Egfr-mutant lung cancer mouse model.
Cancer Sci., in press (2026)

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