Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Takahashi, M., Okamoto, Y., Kato, Y., Shirahama, H., Tsukahara, S., Sugimoto, Y. and Tomida, A.
Activating mutations in EGFR and PI3K promote ATF4 induction for NSCLC cell survival during amino acid deprivation.
Heliyon, in press (2023)
Tanaka, M. and Nakamura, T.
Targeting epigenetic aberrations of sarcoma in CRISPR era.
Genes Chromosomes Cancer, in press (2023)
Yamashita, K., Baba, S., Togashi, Y., Dobashi, A., Ae, K., Matsumoto, S., Tanaka, M., Nakamura, T. and Takeuchi, K.
Clinicopathologic and genetic characterization of angiofibroma of soft tissue: a study of 12 cases including two cases with AHRR::NCOA3 gene fusion.
Histopathology, in press (2023)
Isoyama, S., Tamaki, N., Noguchi, Y., Okamura, M., Yoshimatsu, Y., Kondo, T., Suzuki, T., Yaguchi, S. and Dan, S.
Subtype-selective induction of apoptosis in translocation-related sarcoma cells induced by PUMA and BIM upon treatment with pan-PI3K inhibitors.
Cell Death Dis., 14, 169 (2023)
Saeki, S., Kumegawa, K., Takahashi, Y., Yang, L., Osako, T., Yasen, M., Otsuji, K., Miyata, K., Yamakawa, K., Suzuka, J., Sakimoto, Y., Ozaki, Y., Takano, T., Sano, T., Noda, T., Ohno, S., Yao, R., Ueno, T. and Maruyama, R.
Transcriptomic intratumor heterogeneity of breast cancer patient-derived organoids may reflect the unique biological features of the tumor of origin.
Breast Cancer Res., 25, 21 (2023)