Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Bernardi, F., Torrejon, J., Basili, I., Van Ommeren, R., Marsaud, V., Yu, H., Talbot, J., Souphron, J., Indersie, E., Forget, A., Bonneau, B., Massiot, A., Alcazar, C., Figeac, L., Bonerandi, E., Cancila, G., Sirbu, O., Yadav, N., Mohanakrishnan, D., Lombard, B., Loew, D., Poullet, P., Liva, S., Lovino, M., Lin, I. H., Nakashima, T., Gharsalli, T., Nicolas, P. A., Yubuki, N., Ribas, R. A., Colsch, B., Chu-Van, E., Castelli, F., Sampaio, J. L., Leboucher, S., Lasgi, C., Besse, L., Soler, M. N., Lo Re, V., Planque, N., Abeysundara, N., Balin, P., Wang, H., Su, H., Wu, X., Cavalli, F. M. G., Saulnier, O., Ficarra, E., Di Marcotullio, L., Kumegawa, K., Maruyama, R., Kawauchi, D., Picard, D., Remke, M., Riffaud, L., Puiseux, C., Bouchoucha, Y., Huybrechts, S., Simbozel, M., Bourdeaut, F., Varlet, P., Puget, S., Blauwblomme, T., Andrianteranagna, M., Planchon, J. M., Dugourd, A., Saez-Rodriguez, J., Barillot, E., Servant, N., Martignetti, L., Rich, J., Kool, M., Pfister, S. M., Agnihotri, S., Suzuki, H., Fanjul, M., Wang, W. J., Tsai, J. W., Sun, R. C., Beccaria, K., Dufour, C., Sarry, J. E., Michealraj, K. A., Taylor, M. D. and Ayrault, O.
Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma.
Cancer Cell, 44, 383-404.e18 (2026)
Miyatake, Y., Kamakura, T., Ikawa, T., Yanagiya, R., Kotaki, R., Kameda, K., Nasu, R. K., Okuyama, K., Hirano, K. I., Hosokawa, H., Hozumi, K., Ohtsuka, M., Kisikawa, T., Shibata, C., Otsuka, M., Maruyama, R., Ando, K., Kurosaki, T., Kawamoto, H. and Kotani, A.
A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency.
eLife, 13, RP101510 (2026)
Furukawa, T., Kumegawa, K., Miyata, K., Takamatsu, M., Iesato, A., Saeki, S., Yang, L., Shibata, C., Takahara, T., Masuda, K., Mie, T., Okamoto, T., Takeda, T., Sasaki, T., Ozaka, M., Tanaka, M., Takahashi, S., Noda, T., Yao, R., Sasahira, N. and Maruyama, R.
Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptional and regulatory programs.
J. Exp. Clin. Cancer Res., in press (2026)
Nakayama, C., Fang, Q., Daigaku, Y., Aoi, Y., Ito, S., Takahashi, M., Shimatani, R., Minamisawa, T., Ozturk, Y., Kimura, H., Shilatifard, A., Tellier, M. and Nojima, T.
NELF prevents transcriptional readthrough into DNA replication zones in cancer cells.
EMBO Rep., in press (2026)
Tanaka, Y., Sakahara, M., Yamanaka, H., Natsume, Y., Kusama, D., Kumegawa, K., Yoshikawa, H., Abe, Y., Okabayashi, K., Matui, S., Kitagawa, Y., Koshikawa, N., Osumi, H., Shinozaki, E., Nagayama, S., Adachi, J., Maruyama, R. and Yao, R.
Ribosome biogenesis as a potential therapeutic target in KRAS mutant colorectal cancer.
Nat. Commun., 17, 1224 (2026)

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