Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Udagawa, C., Horinouchi, H., Shiraishi, K., Kohno, T., Okusaka, T., Ueno, H., Tamura, K., Ohe, Y. and Zembutsu, H.
Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease.
PLoS One, in press (2019)
Hara-Nakano, M., Udagawa, C., Shimo, A., Kojima, Y., Yoshie, R., Zaha, H., Abe, N., Tokiwa, M., Uensoko, M., Tamura, K., Shimoi , T., Yoshida, M., Yoshida, T., Sakamoto, H., Kato, K., Mushiroda, T., Tsugawa, K. and Zembutsu, H.
A genome-wide association study identifies five novel genetic markers for trastuzumab-induced cardiotoxicity in Japanese population.
Biol. Pharm. Bull., in press (2019)
Katayama, R., Gong, B., Togashi, N., Miyamoto, M., Kiga, M., Iwasaki, S., Kamai, Y., Tominaga, Y., Takeda, Y., Kagoshima, Y., Shimizu, Y., Seto, Y., Oh-hara, T., Koike, S., Nakao, N., Hanazawa, H., Watanabe, K., Yoda, S., Yanagitani, N., Hata, A. N., Shaw, A. T., Nishio, M., Fujita, N. and Isoyama, T.
The new-generation selective ROS1/NTRK Inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models
Nat. Commun., in press (2019)

ニュースリリース文章はこちら
Suzuki, Y., Kobayashi, K., Wakisaka, Y., Deng, D., Tanaka, S., Huang, C. J., Lei, C., Liu, H., Fujiwaki, Y., lee, S., isozaki, A., Kasai, Y., hayakawa, T., Sakuma, S., Arai, F., Koizumi, K., Tezuka, H., Inaba, M., hiraki, K., Ito, T., Hase, M., Matsusaka, S., Shiba, K., Suga, K., Nishikawa, M., Jona, M., Yatomi, Y., Yaxiaer, Y., Tanaka, Y., Sugimura, T., Nitta, N., Goda, K. and Yasuyuki, O.
Label-free chemical imaging flow cytometry by high-speed multicolor stimulated Raman scattering.
Proc. Natl. Acad. Sci. U. S. A., in press (2019)
Okada, K., Araki, M., Sakashita, T., Ma, B., Kanada, R., Yanagitani, N., Horiike, A., Koike, S., Oh-Hara, T., Watanabe, K., Tamai, K., Maemondo, M., Nishio, M., Ishikawa, T., Okuno, Y., Fujita, N. and Katayama, R.
Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance.
EBioMedicine, 41, 105-119 (2019)

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