Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Akhmetzianova, R., Taniguchi, T., Sasaki, N., Homme, M., Machida, Y., Okahashi, N., Soga, T., Thumkeo, D., Matsuda, F., Takahashi, C., Kitajima, S. and Kohno, S.
Pyruvate carboxylase drives therapeutic resistance to KRAS G12C inhibitors in KEAP1-mutant lung cancer.
Cell Death Dis., in press (2026)
Maezawa, M., Maruyama, R. and Inokuma, H.
Altered histone modifications H3K4me3 and H3K27ac are associated with abnormal clonality of peripheral B-cells in cattle with bovine leukemia virus.
Vet. Microbiol., 322, 111250 (2026)
Nishiguchi, S., Yokomura, M., Gomibuchi, Y., Nagano, S., Yasunaga, T., Hirohashi, Y., Kawamoto, H., Takagi, S. and Katayama, R.
P-selectin on activated platelets inhibits the anti-tumor activity of CD8+ T cells through PSGL-1 binding.
Cancer Immunol. Immunother.,  in press (2026)
Miyata, K., Yang, L., Yang, Y., Kumegawa, K. and Maruyama, R.
Clonal lineage tracing and parallel multiomics profiling reveal transcriptional heterogeneity induced by ARID1A deficiency.
Sci. Adv., in press (2026)
Utsumi, T., Nagasaka, M., Azuma, H., Thwin, K. K., Uchibori, K., Miyauchi, E., Hayashi, H., Nishio, M., Okamoto, I. and Katayama, R.
BMF deficiency promotes drug-tolerant persister cell formation in ALK/ROS1-positive lung cancer.
Cell Death Dis., in press (2026)

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