Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Sakaguchi, H., Katayama, R., Matsumoto, M., Nishiyama, A., Matsumoto, K., Tajima, A., Miyagi, S., Toyama, T., Mizuta, H., Furugaki, K., Yoshiura, S. and Takeuchi, S.
Plasma cfDNA analysis of alectinib resistance-related gene alterations in the J-ALEX study.
ESMO Open, 10, 105574 (2025)
Loo, T. M., Zhou, X., Tanaka, Y., Sugawara, S., Yamauchi, S., Kawasaki, H., Matsuoka, Y., Sugiura, Y., Sakuma, S., Yamanishi, Y., Yotsumoto, S., Dodo, K., Shirasaki, Y., Kamatani, T. and Takahashi, A.
Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis.
Nat. Commun., 16, 6617 (2025)
Huang, T., Takagi, S., Koike, S. and Katayama, R.
Inhibition of anti-apoptotic Bcl-2 family members promotes synergistic cell death with ER stress inducers by disrupting autophagy in glioblastoma.
Cell Death Discov., in press (2025)
Ishiguro, K., Kitajima, H., Niinuma, T., Maruyama, R., Tsukahara, T., Hirohashi, Y., Takaya, A., Kumegawa, K., Yoshido, A., Sekiguchi, S., Sasaki, H., Yorozu, A., Toyota, M., Kai, M., Torigoe, T., Nakase, H. and Suzuki, H.
DOT1L inhibition reprograms innate immunity to potentiate immunomodulatory drug responses in multiple myeloma.
Cancer Lett., 217941 (2025)
Sudo, G., Yamamoto, E., Niinuma, T., Saito, M., Kitajima, H., Ishiguro, K., Yorozu, A., Toyota, M., Aoki, H., Mitsuhashi, K., Yoshii, S., Yamano, H. O., Idogawa, M., Maruyama, R., Sugai, T., Nakase, H. and Suzuki, H.
Concurrent hypermethylation of CpG islands and hypomethylation of CpG-poor regions are associated with gastric cancer risk after Helicobacter pylori eradication.
Gastric Cancer, in press (2025)

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