Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Fujimura, T., Furugaki, K., Mizuta, H., Muraoka, S., Nishio, M., Adachi, J., Uchibori, K., Miyauchi, E., Hayashi, H., Katayama, R. and Yoshiura, S.
Targeting ErbB and tankyrase1/2 prevent the emergence of drug-tolerant persister cells in ALK-positive lung cancer.
NPJ Precis. Oncol., 264, in press (2024)

Okazaki, F., Yorozu, A., Sekiguchi, S., Niinuma, T., Maruyama, R., Kitajima, H., Yamamoto, E., Ishiguro, K., Toyota, M., Hatanaka, Y., Nishiyama, K., Ogi, K., Kai, M., Takano, K., Ichimiya, S., Miyazaki, A. and Suzuki, H.
AEBP1 is a negative regulator of skeletal muscle cell differentiation in oral squamous cell carcinoma.
Sci. Rep., 14, 27425 (2024)
Watanabe, K., Yamamoto, T., Fujita, T., Hino, S., Hino, Y., Yamazaki, K., Ohashi, Y., Sakuraba, S., Kono, H., Nakao, M., Ochiai, K., Dan, S. and Saitoh, N.
Metabolically inducing defects in DNA repair sensitizes BRCA–wild-type cancer cells to replication stress.
Science signaling, 17, in press (2024)

Yamauchi, S., Sugiura, Y., Yamaguchi, J., Zhou, X., Takenaka, S., Odawara, T., Fukaya, S., Fujisawa, T., Naguro, I., Uchiyama, Y., Takahashi, A. and Ichijo, H.

Mitochondrial fatty acid oxidation drives senescence.
Sci. Adv., 10, eado5887 (2024)
 
Otsuji, K., Takahashi, Y., Osako, T., Kobayashi, T., Takano, T., Saeki, S., Yang, L., Baba, S., Kumegawa, K., Suzuki, H., Noda, T., Takeuchi, K., Ohno, S., Ueno, T. and Maruyama, R.
Serial single-cell RNA sequencing unveils drug resistance and metastatic traits in stage IV breast cancer.
NPJ Precis. Oncol., (2024)

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