Recent Publications

Recent Publications

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2017

Dec 04, 2017
Ito, M., Hayashi, K., Minamisawa, T., Homma, S., Koido, S. and Shiba, K.
Encryption of agonistic motifs for TLR4 into artificial antigens augmented the maturation of antigen-presenting cells.
PLoS One, 12, e0188934 (2017)
Nov 10, 2017
Yoshida, M., Hibino, K., Yamamoto, S., Matsumura, S., Yajima, Y. and Shiba, K.
Preferential capture of EpCAM-expressing extracellular vesicles on solid surfaces coated with an aptamer-conjugated zwitterionic polymer.
Biotechnol Bioeng, in press (2017)
Oct 23, 2017
Tanaka, M., Yoshimoto, T. and Nakamura, T.
A double-edged sword: the world according to Capicua in cancer.
Cancer Sci., in press (2017)
Sep 26, 2017
Osako, T., Iwase, T., Ushijima, M., Yonekura, R., Ohno, S. and Akiyama, F.
A new molecular-based lymph node staging classification determines the prognosis of breast cancer patients.
Br. J. Cancer., in press (2017)
Aug 29, 2017
Takemoto, A., Miyata, K. and Fujita, N.
Platelet-activating factor podoplanin: from discovery to drug development.
Cancer and metastasis reviews, 36, 225-234 (2017)
Aug 22, 2017
Katayama, R.
Therapeutic strategies and mechanisms of drug resistance in Anaplastic Lymphoma Kinase (ALK)-rearranged lung cancer.
Pharmacol. Ther., 117, 1-8 (2017)
Jul 28, 2017
Fuse, J. M., Okada, K., Oh-hara, T., Ogura, H., Fujita, N. and Katayama, R.
Mechanisms of resistance to NTRK inhibitors and therapeutic strategies in NTRK1-rearranged cancers.
Mol. Cancer Ther., 16, 2130-2143 (2017)
Jul 19, 2017
Ogura, H., Nagatake-Kobayashi, Y., Adachi, J., Tomonaga, T., Fujita, N. and Katayama, R.
TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
Sci. Rep., 7, 5519 (2017)
Jul 13, 2017
N. Tsuyama, R. Asaka, A. Dobashi, S. Baba, Y. Mishima, K. Ueda, M. Oguchi, H. Tsuji, K. hatake and K. Takeuchi.
Epstein-Barr virus-negative extranodal “true” natural killer-cell lymphoma harbouring a KDM6A mutation.
Hematol. Oncol., in press (2017)
Jun 23, 2017
Miyata, K., Takemoto, A., Okumura, S., Nishio, M. and Fujita, N.
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation.
Sci. Rep., 7, 4059 (2017)
Jun 19, 2017
Nakamura, T., Okabe, S., Yoshida, H., Iida, K., Ma, Y., Sasaki, S., Yamori, T., Shin-Ya, K., Nakano, I., Nagasawa, K. and Seimiya, H.
Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.
Sci Rep, 7, 3605 (2017)

Jun 07, 2017
Takasugi, M., Okada, R., Takahashi, A., Chen, D. V., Watanabe, S. and Hara, E.
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Nat. Commun., doi:10.1038/ncomms15728 (2017)
May 25, 2017
Mashima, T., Taneda, Y., Jang, M. K., Mizutani, A., Muramatsu, Y., Yoshida, H., Sato, A., Tanaka, N., Sugimoto, Y. and Seimiya, H.
mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
Oncotarget, doi: 10.18632/oncotarget.18146 (2017)
May 25, 2017
Migita, T., Ueda, A., Ohishi, T., Hatano, M., Seimiya, H., Horiguchi, S., Koga, F. and Shibasaki, F.
Epithelial-mesenchymal transition promotes SOX2 and NANOG expression in bladder cancer.
Lab. Invest., 97, 567-576 (2017)
May 19, 2017
N. Tsuyama, S. Sakata, S. Baba, Y. Mishima, N. Nishimura, K. Ueda, M. Yokoyama, Y. Terui, K. Hatake, M. Kitagawa, N. Ishizuka, N. Tomita and K. Takeuchi.
BCL2 expression in DLBCL: reappraisal of immunohistochemistry with new criteria for therapeutic biomarker evaluation.
Blood, in press (2017)
May 17, 2017
Takahashi, A., Okada, R., Nagao, K., Kawamata, Y., Hanyu, A., Yoshimoto, S., Takasugi, M., Watanabe, S., Kanemaki, M., Obuse, C. and Hara, E.
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
Nat. Commun., 8, 15287 (2017)
Apr 21, 2017
Yoshimoto, T., Motoi, N., Yamamoto, N., Nagano, H., Ushijima, M., Matsuura, M., Okumura, S., Yamaguchi, T., Fukayama, M. and Ishikawa, Y.
Pulmonary carcinoids and low-grade gastrointestinal neuroendocrine tumors show common nicroRNA expression profiles, different from adenocarcinomas and small cell carcinomas.
Neuroendocrinology, in press (2017)
Apr 14, 2017
T. Yoshimoto, M. Tanaka, M. Homme, Y. Yamazaki, Y. Takazawa, C. R. Antonescu and T. Nakamura.
CIC-DUX4 induces small round cell sarcomas distinct from Ewing sarcoma.
Cancer research, in press, (2017)
Mar 27, 2017
Tsuyama, N., Ennishi, D., Yokoyama, M., Baba, S., Asaka, R., Mishima, Y., Terui, Y., Hatake, K. and Takeuchi, K.
Clinical and prognostic significance of aberrant T-cell marker expression in 225 cases of de novo diffuse large B-cell lymphoma and 276 cases of other B-cell lymphomas.
Oncotarget, 16532 (2017)
Mar 17, 2017
Tamura, T., Kiura, K., Seto, T., Nakagawa, K., Maemondo, M., Inoue, A., Hida, T., Yoshioka, H., Harada, M., Ohe, Y., Nogami, N., Murakami, H., Kuriki, H., Shimada, T., Tanaka, T., Takeuchi, K. and Nishio, M.
Three-year follow-up of an alectinib phase I/II study in ALK-positive non-small-cell lung cancer: AF-001JP.
J Clin Oncol, JCO2016705749 (2017)
Mar 16, 2017
Yoshimura, K., Inui, N., Karayama, M., Inoue, Y., Enomoto, N., Fujisawa, T., Nakamura, Y., Takeuchi, K., Sugimura, H. and Suda, T.
Successful crizotinib monotherapy in EGFR-mutant lung adenocarcinoma with acquired MET amplification after erlotinib therapy.
Respir. Med. Case Rep., 20, 160-163 (2017)
Mar 14, 2017
Uchibori, K., Inase, N., Araki, M., Kamada, M., Sato, S., Okuno, Y., Fujita, N. and Katayama, R.
Brigatinib combined with anti-EGFR antibody overcomes Osimertinib resistance in EGFR-mutated non-small-cell lung cancer.
Nat. Commun., 8, 14768 (2017)
Feb 24, 2017
Inamura, K., Yokouchi, Y., Kobayashi, M., Ninomiya, H., Sakakibara, R., Subat, S., Nagano, H., Nomura, K., Okumura, S., Sibutani, T. and Ishikawa, Y.
Association of tumor TROP2 expression with prognosis varies among lung cancer subtypes.
Oncotarget, in press (2017)
Feb 20, 2017
S. Takeuchi, K. Fukuda, T. Yamada, S. Arai, S. Takagi, A. Ishii, S. Ochiai, S. Iwakiri, K. Itoi, H. Uehara, H. Nishihara, N. Fujita and S. Yano.
Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation.
Cancer Science, in press (2017)
Feb 17, 2017
T. Ohishi, H. Yoshida, M. Katori, T. Migita, Y. Muramatsu, M. Miyake, Y. Ishikawa, A. Saiura, S. Iemura, T. Natsume and H. Seimiya.
Tankyrase-binding protein TNKS1BP1 regulates actin cytoskeleton rearrangement and cancer cell invasion.
Cancer Research, in press (2017)
Feb 10, 2017
Takemoto, A., Okitaka, M., Takagi, S., Takami, M., Sato, S., Nishio, M., Okumura, S. and Fujita, N.
A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis.
Sci. Rep., 7, 42186 (2017)
Feb 10, 2017
Tanaka, N., Mashima, T., Mizutani, A., Sato, A., Aoyama, A., Gong, B., Yoshida, H., Muramatsu, Y., Nakata, K., Matsuura, M., Katayama, R., Nagayama, S., Fujita, N., Sugimoto, Y. and Seimiya, H.
APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer.
Mol. Cancer Ther., in press (2017)
Feb 08, 2017
Katayama, R.
Therapeutic strategies and mechanisms of drug resistance in Anaplastic Lymphoma Kinase (ALK)-rearranged lung cancer.
Pharmacology &Therapeutics, in press (2017)

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