Recent Publications

Recent Publications

2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013

2021

Sep 10, 2021
Osako, T., Kurisaki-Arakawa, A., Dobashi, A., Togashi, Y., Baba, S., Shiozawa, S., Ishigame, H., Ishige, H., Ohno, S., Ishikawa, Y. and Takeuchi, K.
Distinct clinicopathologic features and possible pathogenesis of localized ALK-positive histiocytosis of the breast.
Am. J. Surg. Pathol., in press (2021)
Aug 30, 2021
Isoyama, S., Mori, S., Sugiyama, D., Kojima, Y., Tada, Y., Shitara, K., Hinohara, K., Dan, S. and Nishikawa, H.

Cancer immunotherapy with PI3K and PD-1 dual-blockade via optimal modulation of T cell activation signal.

J. Immunother. Cancer, 9,  (2021)

 

Aug 24, 2021
Miyata, K., Imai, Y., Hori, S., Nishio, M., Loo, T. M., Okada, R., Yang, L., Nakadai, T., Maruyama, R., Fujii, r., Ueda, K., Jiang, L., Zheng, H., Toyokuni, S., Sakata, T., Shirahige, K., Kojima, R., Nakayama, M., Oshima, M., Nagayama, S., Hara, E. and Takahashi, A.
Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.
Proc. Natl. Acad. Sci. U. S. A., 118, e2025647118 (2021)

Aug 16, 2021
Iwao, Y., Okamoto, Y., Shirahama, H., Tsukahara, S. and Tomida, A.
eIF4B enhances ATF4 expression and contributes to cellular adaptation to asparagine limitation in BRAF-mutated A375 melanoma.
Biochem. Biophys. Res. Commun., 573, 93-99 (2021)
Aug 16, 2021
Tanaka, M. and Nakamura, T.
Modeling fusion gene-associated sarcoma: Advantages for understanding sarcoma biology and pathology.
Pathol. Int.,  in press (2021)
Aug 16, 2021
Yoshino, S., Tanaka, M., Sunami, Y., Takahara, T., Yamazaki, Y., Homme, M., Niibori-Nambu, A., Osato, M., Minami, T., Ishihara, K. and Nakamura, T.
Trib1 promotes the development of acute myeloid leukemia in a Ts1Cje mouse model of Down syndrome.
Leukemia,  in press
Aug 03, 2021
Otsuji, K., Sasaki, T., Tanabe, M. and Seto, Y.

Quantitative assessment of HER2 gene amplification of breast cancer using droplet digital PCR.  

Pathol. Int.,  in press (2021)

 

Jul 26, 2021
Mashima, T., Wakatsuki, T., Kawata, N., Jang, M. K., Nagamori, A., Yoshida, H., Nakamura, K., Migita, T., Seimiya, H. and Yamaguchi, K.

Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo.

Sci. Rep.,  in press (2021)


Jul 26, 2021
Takagi, S., Sasaki, Y., Koike, S., Takemoto, A., Seto, Y., Haraguchi, M., Ukaji, T., Kawaguchi, T., Sugawara, M., Saito, M., Funauchi, Y., Ae, K., Matsumoto, S., Fujita, N. and Katayama, R.
Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis.
Oncogene,  in press (2021)

Jul 26, 2021
Seimiya, H., Nagasawa, K. and Shin-Ya, K.
Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics.
J. Antibiot.,  in press (2021)

Jul 15, 2021
Niinuma, T., Kitajima, H., Yamamoto, E., Maruyama, R., Aoki, H., Harada, T., Ishiguro, K., Sudo, G., Toyota, M., Yoshido, A., Kai, M., Nakase, H., Sugai, T. and Suzuki, H.
An integrated epigenome and transcriptome analysis to clarify the effect of epigenetic inhibitors on GIST.
Anticancer Res., 41, 2817-2828 (2021)
Jul 15, 2021
Jo, M., Kusano, Y. and Hirota, T.
Unraveling pathologies underlying chromosomal instability in cancers.
Cancer Sci., in press (2021)
Jul 15, 2021
Matsui, S. and Nozawa, R. S.
RNA impacts formation of biomolecular condensates in the nucleus.
Biomolecular Research (Tokyo), in press (2021)
Jul 12, 2021
Minegishi, R., Gotoh, O., Tanaka, N., Maruyama, R., Chang, J. T. and Mori, S.
A method of sample-wise region-set enrichment analysis for DNA methylomics.
Epigenomics, in press (2021)
Jun 18, 2021
Osako, T.
How can we better distinguish metastatic tumors from primary tumors in the breast?
Expert Rev. Anticancer Ther.,  in press (2021)

May 20, 2021
Akiya, M., Osako, T., Morizono, H., Furuta, N., Kikuchi, M., Ueno, T., Ohno, S. and Takeuchi, K.
Myofibroblastoma of the breast showing rare palisaded morphology and uncommon desmin- and CD34-negative immunophenotype: A case report.
Pathol. Int., in press (2021)
Apr 20, 2021
Yoshizawa, T., Uchibori, K., Araki, M., Matsumoto, S., Ma, B., Kanada, R., Seto, Y., Oh-Hara, T., Koike, S., Ariyasu, R., Kitazono, S., Ninomiya, H., Takeuchi, K., Yanagitani, N., Takagi, S., Kishi, K., Fujita, N., Okuno, Y., Nishio, M. and Katayama, R.
Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.
NPJ precision oncology, 5, 32 (2021)
Apr 12, 2021
Yamamoto, S., Okamura, K., Fujii, R., Kawano, T., Ueda, K., Yajima, Y. and Shiba, K.
Specimen-specific drift of densities defines distinct subclasses of extracellular vesicles from human whole saliva.
PLoS One, 16, e0249526 (2021)
Apr 07, 2021
Tasaki, Y., Suzuki, M., Katsushima, K., Shinjo, K., Iijima, K., Murofushi, Y., Naiki-Ito, A., Hayashi, K., Qiu, C., Takahashi, A., Tanaka, Y., Kawaguchi, T., Sugawara, M., Kataoka, T., Naito, M., Miyata, K., Kataoka, K., Noda, T., Gao, W., Kataoka, H., Takahashi, S., Kimura, K. and Kondo, Y.
Cancer-specific targeting of taurine-upregulated gene 1 enhances the effects of chemotherapy in pancreatic cancer.
Cancer Res.,  in press (2021)
Apr 06, 2021
Uchida, K. S. K., Jo, M., Nagasaka, K., Takahashi, M., Shindo, N., Shibata, K., Tanaka, K., Masumoto, H., Fukagawa, T. and Hirota, T.
Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation.
Curr. Biol., in press (2021)
Apr 06, 2021
Watanabe, M., Bhawala, U. K., Takemoto, S., Nishiyama, N., Nakahara, Y., Tatematsu, K. I., Sezuts, H., Kuwabara, N., Minamisawa, T., Shiba, K. and Asakura, T.
Bio-functionalized titanium surfaces with modified silk fibroin carrying titanium binding motif to enhance the ossific differentiation of MC3T3-E1.
Biotechnol. Bioeng., in press (2021)
Mar 19, 2021
Ukaji, T., Takemoto, A., Shibata, H., Kakino, M., Takagi, S., Katayama, R. and Fujita, N.
Novel knock‐in mouse model for the evaluation of therapeutic efficacy and toxicity of human podoplanin‐targeting agents.
Cancer Sci., in press (2021)
Mar 12, 2021
Ariyasu, R., Uchibori, K., Sasaki, T., Tsukahara, M., Kiyotani, K., Yoshida, R., Ono, Y., Kitazono, S., Ninomiya, H., Ishikawa, Y., Mizukami, Y., Yanagitani, N., Fujita, N., Nishio, M. and Katayama, R.
Monitoring EGFR C797S mutation in Japanese NSCLC patients with serial cell free DNA evaluation using digital droplet PCR.
Cancer Sci., in press (2021)
Mar 12, 2021
Okamoto, T., DuVerle, D. A., Yaginuma, K., Natsume, Y., Yamana, H., Fukuda, M., Yamamoto, F., Pe’rraudeau, F., Srivastava, U., Kashima, Y., Suzuki, A., Kuze, Y., Takahashi, Y., Ueno, M., Sakai, Y., Noda, T., Tsuda, K., Suzuki, Y., Nagayama, S. and Yao, R.
Comparative analysis of patient-matched PDOs revealed a reduction in OLFM4-associated clusters in metastatic lesions in colorectal cancer.
Stem Cell Rep., in press (2021)
Mar 02, 2021
Yasuda, T., Koiwa, M., Yonemura, A., Miyake, K., Kariya, R., Kubota, S., Yokomizo-Nakano, T., Yasuda-Yoshihara, N., Uchihara, T., Itoyama, R., Bu, L., Fu, L., Arima, K., Izumi, D., Iwagami, S., Eto, K., Iwatsuki, M., Baba, Y., Yoshida, N., Ohguchi, H., Okada, S., Matsusaki, K., Sashida, G., Takahashi, A., Tan, P., Baba, H. and Ishimoto, T.

Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.

Cell Rep., 34, 108779 (2021)

Feb 25, 2021
Mizuta, H., Okada, K., Araki, M., Adachi, J., Takemoto, A., Kutkowska, J., Maruyama, K., Yamagitani, N., Oh-hara, T., Watanabe, K., Tamai, K., Friboulet, l., Katayama, K., Ma, B., Sasakura, Y., Sagae, Y., Kukimoto-Niino, K., Shirouzu, M., Takagi, S., Simizu, S., Nishio, M., Okuno, Y., Fujita, N. and Katayama, R.
Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer.
Nat. Commun., 12, 1261 (2021)
Feb 15, 2021
Ikeda, A., Nagayama, S., Sumazaki, M., Konishi, M., Fujii, R., Saichi, N., Muraoka, S., Saigusa, D., Shimada, H., Sakai, Y. and Ueda, K.
Colorectal cancer-derived CAT1-positive extracellular vesicles alter nitric oxide metabolism in endothelial cells and promote angiogenesis.
Mol. Cancer Res.,  in press (2021)
Feb 12, 2021
Hiraga(Kondo), C., Yamamoto, S., Hashimoto, S., Kasahara, M., Minamisawa, T., Matsumura, S., Katakura, A., Yajima, Y., Nomura, T. and Shiba, K.
Pentapartite fractionation of particles in oral fluids by differential centrifugation.
Sci. Rep., 11, 3326 (2021)
Feb 04, 2021
Yoshida, R., Hagio, T., Kaneyasu, T., Gotoh, O., Osako, T., Tanaka, N., Amino, S., Yaguchi, N., Nakashima, E., Kitagawa, D., Ueno, T., Ohno, S., Nakajima, T., Nakamura, S., Miki, Y., Hirota, T., Takahashi, S., Matsuura, M., Noda, T. and Mori, S.
Pathogenicity assessment of variants for breast cancer susceptibility genes based on BRCAness of tumor sample.
Cancer Sci., in press (2021)
Jan 28, 2021
Obara, R., Kamiya, M., Tanaka, Y., Abe, A., Kojima, R., Kawaguchi, T., Sugawara, M., Takahashi, A., Noda, T. and Urano, Y.
γ-Glutamyltranspeptidase (GGT)-Activatable Fluorescence Probe for Durable Tumor Imaging.
Angewandte Chemie (International ed. in English), 60, 2125-2129 (2021)
Jan 21, 2021
Shindo, N., Otsuki, M., Uchida, K. and Hirota, T.
Prolonged mitosis causes separase deregulation and chromosome nondisjuction.
Cell Rep., 34, 108652 (2021)

Return to Top of Page