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Recent Publications

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Campisi, M., Sundararaman, S. K., Shelton, S. E., Knelson, E. H., Mahadevan, N. R., Yoshida, R., Tani, T., Ivanova, E., Cañadas, I., Osaki, T., Lee, S. W. L., Thai, T., Han, S., Piel, B. P., Gilhooley, S., Paweletz, C. P., Chiono, V., Kamm, R. D., Kitajima, S. and Barbie, D. A.
Tumor-derived cGAMP regulates activation of the vasculature.
Front. Immunol., 11, 2090 (2020)
Kitajima, S., Li, F. and Takahashi, C.
Tumor milieu controlled by RB tumor suppressor.
Int. J. Mol. Sci., 21, 2450 (2020)
Sehgal, K., Portell, A. J., Ivanova, E. V., Lizotte, P. H., Mahadevan, N. R., Greene, J. R., Vajdi, A., Gurjao, C., Teceno, T., Taus, L. J., Thai, T. C., Kitajima, S., Liu, D., Tani, T., Noureddine, M., Lau, C. J., Kirschmeier, P. T., Liu, D., Giannakis, M., Jenkins, R. W., Gokhale, P. C., Goldoni, S., Pinzon-Ortiz, M., Hastings, W. D., Hammerman, P., Miret, J. J., Paweletz, C. P. and Barbie, D. A.
Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.
J. Clin. Invest., in press (2020)
Osumi, H., Muroi, A., Sakahara, M., Kawachi, H., Okamoto, T., Natsume, Y., Yamanaka, H., Takano, H., Kusama, D., Shinozaki, E., Ooki, A., Yamaguchi, K., Ueno, M., Takeuchi, K., Noda, T., Nagayama, S., Koshikawa, N. and Yao, R.
Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient.
Sci. Rep., 10, 17455 (2020)
Gotoh, O., Kiyotani, K., Chiba, T., Sugiyama, Y., Takazawa, Y., Nemoto, K., Kato, K., Tanaka, N., Nomura, H., Hasegawa, K., Fujiwara, K., Takamatsu, S., Matsumura, N., Noda, T. and Mori, S.
Immunogenomic Landscape of Gynecologic Carcinosarcoma.
Gynecol. Oncol., in press (2020)
Furuta, H., Araki, M., Masago, K., Sagae, Y., Fujita, S., Seto, K., Shimizu, J., Horio, Y., Sasaki, E., Hosoda, W., Katayama, R., Okuno, Y. and Hida, T.
Novel resistance mechanisms including L1196Q, P1094H, and R1248_D1249insertion in three patients with non-small-cell lung cancer following ALK tyrosine kinase inhibitor treatment.
J. Thorac. Oncol., in press (2020)
Ariyasu, R., Yanagitani, N., Tadokoro, K., Yamaguchi, T., Uchibori, K., Kitazono, S., Fujita, N., Katayama, R. and Nishio, M.
Efficacy of EGFR tyrosine kinase inhibitors in patients having EGFR-activating mutations with or without BIM polymorphisms.
Cancer Chemother. Pharmacol., 86, 517-525 (2020)
Kato, Y., Kunimasa, K., Takahashi, M., Harada, A., Nagasawa, I., Osawa, M., Sugimoto, Y. and Tomida, A.
GZD824 inhibits GCN2 and sensitizes cancer cells to amino acid starvation stress.
Molecular Pharmacology, in press (2020)
Nosol, K., Romane, K., Irobalieva, R. N., Alam, A., Kowal, J., Fujita, N. and Locher, K. P.
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc. Natl. Acad. Sci. U. S. A., in press (2020)
Sonoda, T., Yanagitani, N., Suga, K., Yoshizawa, T., Nishikawa, S., Kitazono, S., Horiike, A., Shiba, K., Ishizuka, T., Nishio, M. and Matsusaka, S.
A novel system to detect circulating tumor cells using two different size-selective microfilters.
Anticancer Res., 40, 5577-5582 (2020)

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