Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Morimura, R., Nada, I., Mizue, Y., Shinozaki, E., Fujita, N., Katayama, R., Matsusaki, M., Hirohashi, Y., Kitano, S. and Torigoe, T.
Engineering a Multilayered 3D Stromal Barrier Model for Quantitative Analysis of T Cell Infiltration and Cytotoxicity.
Acta Biomater., in press (2025)
Sakaguchi, H., Katayama, R., Matsumoto, M., Nishiyama, A., Matsumoto, K., Tajima, A., Miyagi, S., Toyama, T., Mizuta, H., Furugaki, K., Yoshiura, S. and Takeuchi, S.
Plasma cfDNA analysis of alectinib resistance-related gene alterations in the J-ALEX study.
ESMO Open, 10, 105574 (2025)
Loo, T. M., Zhou, X., Tanaka, Y., Sugawara, S., Yamauchi, S., Kawasaki, H., Matsuoka, Y., Sugiura, Y., Sakuma, S., Yamanishi, Y., Yotsumoto, S., Dodo, K., Shirasaki, Y., Kamatani, T. and Takahashi, A.
Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis.
Nat. Commun., 16, 6617 (2025)
Huang, T., Takagi, S., Koike, S. and Katayama, R.
Inhibition of anti-apoptotic Bcl-2 family members promotes synergistic cell death with ER stress inducers by disrupting autophagy in glioblastoma.
Cell Death Discov., in press (2025)
Ishiguro, K., Kitajima, H., Niinuma, T., Maruyama, R., Tsukahara, T., Hirohashi, Y., Takaya, A., Kumegawa, K., Yoshido, A., Sekiguchi, S., Sasaki, H., Yorozu, A., Toyota, M., Kai, M., Torigoe, T., Nakase, H. and Suzuki, H.
DOT1L inhibition reprograms innate immunity to potentiate immunomodulatory drug responses in multiple myeloma.
Cancer Lett., 217941 (2025)

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