Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Iesato, A., Suzuka, J., Otsuji, K., Osako, T., Yamashita, N., Inoue, Y., Maeda, T., Uehiro, N., Yoshida, K., Takahashi, Y., Kumegawa, K., Saeki, S., Yang, L., Tsuchiya, A., Sakiyama, K., Tanaka, M., Sakai, T., Ohno, S., Noda, T., Ueno, T. and Maruyama, R.
Axillary adipose tissue-derived lymphatic endothelial cells exhibit distinct transcriptomic signatures reflecting lymphatic invasion status in breast cancer.
Breast Cancer Res., 27, 109 (2025)
Wang, W., Kumegawa, K., Chapman, O. S., Shiraishi, R., Xiao, Z., Okonechnikov, K., Sun, Y., Pfister, S. M., Feng, W., Uesaka, N., Hoshino, M., Takahashi, S., Korshunov, A., Chavez, L., Maruyama, R. and Kawauchi, D.
Chromatin Modification Abnormalities by CHD7 and KMT2C Loss Promote Medulloblastoma Progression.
Cell Rep., 44, 115673 (2025)
Ogawa, A., Izumikawa, K., Tate, S., Isoyama, S., Mori, M., Fujiwara, K., Watanabe, S., Ohga, T., Jo, U., Taniyama, D., Kitajima, S., Tanaka, S., Onji, H., Kageyama, S.-I., Yamamoto, G., Saito, H., Morita, T. Y., Okada, M., Natsumeda, M., Nagahama, M., Kobayashi, J., Ohashi, A., Sasanuma, H., Higashiyama, S., Dan, S., Pommier, Y. and Murai, J.
SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis.
Mol. Cell, in press (2025)
Utsumi, T., Mizuta, H., Seto, Y., Uchibori, K., Nishio, M., Okamoto, I. and Katayama, R.
AXL-mediated drug resistance in ALK-rearranged NSCLC enhanced by GAS6 from macrophages and MMP11 positive fibroblasts.
Cancer Sci., in press (2025)
Maruyama, K., Shimizu, Y., Nomura, Y., Oh-hara, T., Takahashi, Y., Nagayama, S., Fujita, N. and Katayama, R.
Mechanisms of KRAS inhibitor resistance in KRAS-mutant colorectal cancer harboring Her2 amplification and aberrant KRAS localization.
npj Precis Oncol, in press (2025)

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