Realizing individualized cancer treatment through patient genome sequencing

Recent Publications

Thanongsak, W., Kawahara, M., Nakamoto, M., Homma, K., Sereemaspun, A., Tachaboonyakiat, W., Ruktanonchai, U., Yoshimoto, K., Katayama, R., Matsusaki, M. and Chirachanchai, S.
Concerted pH-responsive performance of chitosan-deoxycholic acid as a polymeric molecular block for cancer cell disruption.
ChemMedChem, 21, e202500587 (2026)
Izumi, H., Sakamoto, T., Uchibori, K., Nishino, K., Sakakibara-Konishi, J., Katayama, R., Nomura, S., Matsumoto, S., Udagawa, H., Shibata, Y., Sakai, T., Nosaki, K., Zenke, Y., Yoh, K., Niho, S. and Goto, K.
Phase 1/2 trial of brigatinib plus panitumumab in patients with osimertinib-resistant EGFR-mutated non-small cell lung cancer harboring EGFR C797S mutation.
Cancer Treat. Res. Commun., 46, 101105 (2026)
Wakita, M., Ito, K., Fujii, K., Sakamoto, D., Mikawa, T., Sugawara, S., Zhou, X., Park, J. H., Miyagawa, H., Motooka, D., Ogasawara, E., Ishihara, N., Takahashi, A., Kondoh, H. and Hara, E.
Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance.
Nature aging, in press (2026)
FuKoichi, J., Kitamura, K., Kawahara, R., Shihoya, W., Nureki, O., Hosoya, S., Nakagawa, R., Mashima, T., Itoh, H., Inoue, M. and Sakurai, K.
Photoaffinity labeling strategy reveals tetraspanin CD9 as a transient target of anticancer Yaku’amide B.
J. Am. Chem. Soc.,  in press (2026)
Moroishi, K., Nakamoto, M., Fujita, S., Kawahara, M., Katayama, R. and Matsusaki, M.
Escape from cell uptake: Drug-free cancer therapeutics regulated by hydrophobicity and negative charge.
Mater. Today Bio, 102752 (2025)

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