1. Original articles
  2. Reviews and book chapters

Original articles


Hamanaka, W., Motoi, N., Ishikawa, S., Ushijima, M., Inamura, K., Hatano, S., Uehara, H., Okumura, S., Nakagawa, K., Nishio, M., Horai, T., Aburatani, H., Matsuura, M., Iwasaki, A., Ishikawa, Y.
A subset of small cell lung cancer with low neuroendocrine expression and good prognosis: a comparison study of surgical and inoperable cases with biopsy.
Hum Pathol, 45, 1045-1056 (2014)
Ono, H., Motoi, N., Nagano, H., Miyauchi, E., Ushijima, M., Matsuura, M., Okumura, S., Nishio, M., Hirose, T., Inase, N., Ishikawa, Y.
Long noncoding RNA HOTAIR is relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer.
Cancer Med, in press (2014)
Osako, T., Iwase, T., Ushijima, M., Horii, R., Fukami, Y., Kimura, K., Matsuura, M., Akiyama, F.
Incidence and prediction of invasive disease and nodal metastasis in preoperatively diagnosed ductal carcinoma in situ.
Cancer Sci, in press (2014)
Tatsukawa, E., Gonda, Y., Kamitakahara, M., Matsuura, M., Ushijima, M., Shibata, Y., Yonezawa, I., Fujiwara, M., Ioku, K., Ikeda, T.
Promotion of normal healing of bone defects under estrogen deficiency by implantation of beta-tricalcium phosphate composed of rod-shaped particles.
J Orthop Res, 32, 189-196 (2014)
Wada, Y., Matsuura, M., Sugawara, M., Ushijima, M., Miyata, S., Nagasaki, K., Noda, T., Miki, Y.
Development of detection method for novel fusion gene using GeneChip exon array.
J Clin Bioinforma, 4, 3 (2014)

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Huang, R.Y., Wong, M.K., Tan, T.Z., Kuay, K.T., Ng, A.H., Chung, V.Y., Chu, Y.S., Matsumura, N., Lai, H.C., Lee, Y.F., Sim, W.J., Chai, C., Pietschmann, E., Mori, S., Low, J.J., Choolani, M., Thiery, J.P.
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).
Cell death & disease, 4, e915 (2013)
Hayano, T., Garg, M., Yin, D., Sudo, M., Kawamata, N., Shi, S., Chien, W., Ding, L.W., Leong, G., Mori, S., Xie, D., Tan, P., Koeffler, H.P.
SOX7 is down-regulated in lung cancer.
J Exp Clin Cancer Res, 32, 17 (2013)
Sudo, M., Chin, T.M., Mori, S., Doan, N.B., Said, J.W., Akashi, M., Koeffler, H.P.
Inhibiting proliferation of gefitinib-resistant, non-small cell lung cancer.
Cancer Chemother Pharmacol, 71, 1325-1334. (2013)
Tan, T.Z., Miow, Q.H., Huang, R.Y., Wong, M.K., Ye, J., Lau, J.A., Wu, M.C., Bin Abdul Hadi, L.H., Soong, R., Choolani, M., Davidson, B., Nesland, J.M., Wang, L.Z., Matsumura, N., Mandai, M., Konishi, I., Goh, B.C., Chang, J.T., Thiery, J.P., Mori, S.
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer.
EMBO Mol Med, 5, 983-998 (2013)
Ushijima, M., Mashima, T., Tomida, A., Dan, S., Saito, S., Furuno, A., Tsukahara, S., Seimiya, H., Yamori, T., Matsuura, M.
Development of a gene expression database and related analysis programs for evaluation of anticancer compounds.
Cancer Sci, 104, 360-368 (2013)
Voon, D.C., Wang, H., Koo, J.K., Chai, J.H., Hor, Y.T., Tan, T.Z., Chu, Y.S., Mori, S., Ito, Y.
EMT-induced stemness and tumorigenicity are fueled by the EGFR/Ras pathway.
PLoS One, 8, e70427 (2013)

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Fujiwara, T., Hiramatsu, M., Isagawa, T., Ninomiya, H., Inamura, K., Ishikawa, S., Ushijima, M., Matsuura, M., Jones, M.H., Shimane, M., Nomura, H., Ishikawa, Y., Aburatani, H.
ASCL1-coexpression profiling but not single gene expression profiling defines lung adenocarcinomas of neuroendocrine nature with poor prognosis.
Lung Cancer, 75, 119-125 (2012)
Kulachai, Y., Miyata, S.
The success of policy implementation against drunk driving in Bangkok: A structural equation moleling.
J Asian Transport Res Soc, in press (2012)
Matsuo, J., Tsukumo, Y., Saito, S., Tsukahara, S., Sakurai, J., Sato, S., Kondo, H., Ushijima, M., Matsuura, M., Watanabe, T., Tomida, A.
Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation.
Mol Cancer Ther, 11, 1082-1091 (2012)
Satoh, Y., Sugai, S., Uehara, H., Mun, M., Sakao, Y., Okumura, S., Nakagawa, K., Ishikawa, Y., Miki, Y., Miyata, S.
Clinical impact of intraoperative detection of carcinoembryonic antigen (CEA) in mRNA in pleural lavage specimens from non-small cell lung cancer.
Thorac Cardiovasc Surg, in press (2012)
Yamada, M., Yao, I., Hayasaka, T., Ushijima, M., Matsuura, M., Takada, H., Shikata, N., Setou, M., Kwon, A.H., Ito, S.
Identification of oligosaccharides from histopathological sections by MALDI imaging mass spectrometry.
Anal Bioanal Chem, 402, 1921-1930 (2012)
Yamamoto, K., Miyata, S., Kameyama, H.
Characteristics of university spin-offs in chemistry on the business relationship with manufactures.
J Chem Eng Jpn, 45, 239-244 (2012)

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Abe, M., Miyata, S., Nishimura, S., Iijima, K., Makita, M., Akiyama, F., Iwase, T.
Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumors.
Breast Cancer, 18, 268-272 (2011)
Akiyoshi, T., Fujimoto, Y., Konishi, T., Kuroyanagi, H., Ueno, M., Oya, M., Miyata, S., Yamaguchi, T.
Prognostic factors for survival after salvage surgery for locoregional recurrence of colon cancer.
Am J Surg, 201, 725-733 (2011)
Hayasaka, T., Goto-Inoue, N., Ushijima, M., Yao, I., Yuba-Kubo, A., Wakui, M., Kajihara, S., Matsuura, M., Setou, M.
Development of imaging mass spectrometry (IMS) dataset extractor software, IMS convolution.
Anal Bioanal Chem, 401, 183-193 (2011)
Ito, Y., Nagasaki, K., Miki, Y., Iwase, T., Akiyama, F., Matsuura, M., Horii, R., Makita, M., Tokudome, N., Ushijima, M., Yoshimoto, M., Takahashi, S., Noda, T., Hatake, K.
Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer.
Cancer Sci, 102, 130-136 (2011)
Katoh, Y., Ikura, T., Hoshikawa, Y., Tashiro, S., Ito, T., Ohta, M., Kera, Y., Noda, T., Igarashi, K.
Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein.
Mol Cell, 41, 554-566 (2011)
Tokunaga, M., Hiki, N., Fukunaga, T., Miki, A., Ohyama, S., Miyata, S., Yamaguchi, T.
Learning curve of laparoscopy-assisted gastrectomy using a standardized surgical technique and an established educational system.
Scand J Surg, 100, 86-91 (2011)

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Hirono, S., Yamaue, H., Hoshikawa, Y., Ina, S., Tani, M., Kawai, M., Ushijima, M., Matsuura, M., Saiki, Y., Saiura, A., Yamamoto, J., Miki, Y., Noda, T.
Molecular markers associated with lymph node metastasis in pancreatic ductal adenocarcinoma by genome-wide expression profiling.
Cancer Sci, 101, 259-266 (2010)
Hoshi, R., Furuta, N., Horai, T., Ishikawa, Y., Miyata, S., Satoh, Y.
Discriminant model for cytologic distinction of large cell neuroendocrine carcinoma from small cell carcinoma of the lung.
J Thorac Oncol, 5, 472-478 (2010)
Ito, Y., Nagasaki, K., Miki, Y., Iwase, T., Akiyama, F., Matsuura, M., Horii, R., Makita, M., Tokudome, N., Ushijima, M., Yoshimoto, M., Takahashi, S., Noda, T., Hatake, K.
Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer.
Cancer Sci, 102, 130-136 (2010)
Orita, Y., Sugitani, I., Matsuura, M., Ushijima, M., Tsukahara, K., Fujimoto, Y., Kawabata, K.
Prognostic factors and the therapeutic strategy for patients with bone metastasis from differentiated thyroid carcinoma.
Surgery, 147, 424-431 (2010)
Yamamoto, Y., Fujisaki, J., Hirasawa, T., Ishiyama, A., Yoshimoto, K., Ueki, N., Chino, A., Tsuchida, T., Hoshino, E., Hiki, N., Fukunaga, T., Sano, T., Yamaguchi, T., Takahashi, H., Miyata, S., Yamamoto, N., Kato, Y., Igarashi, M.
Therapeutic outcomes of endoscopic submucosal dissection of undifferentiated-type intramucosal gastric cancer without ulceration and preoperatively diagnosed as 20 millimetres or less in diameter.
Dig Endosc, 22, 112-118 (2010)
Yokoyama, T., Kanno, Y., Yamazaki, Y., Takahara, T., Miyata, S., Nakamura, T.
Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis.
Blood, 116, 2768-2775 (2010)
日本統計学会誌 Series J, 39, 369-391 (2010)

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Abe, M., Miyata, S., Nishimura, S., Iijima, K., Makita, M., Akiyama, F., Iwase, T.
Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumors.
Breast Cancer, in press (2009)
Akiyoshi, T., Kuroyanagi, H., Oya, M., Konishi, T., Fukuda, M., Fujimoto, Y., Ueno, M., Miyata, S., Yamaguchi, T.
Factors affecting the difficulty of laparoscopic total mesorectal excision with double stapling technique anastomosis for low rectal cancer.
Surgery, 146, 483-489 (2009)
Alper, O., Stetler-Stevenson, W.G., Harris, L.N., Leitner, W.W., Ozdemirli, M., Hartmann, D., Raffeld, M., Abu-Asab, M., Byers, S., Zhuang, Z., Oldfield, E.H., Tong, Y., Bergmann-Leitner, E., Criss, W.E., Nagasaki, K., Mok, S.C., Cramer, D.W., Karaveli, F.S., Goldbach-Mansky, R., Leo, P., Stromberg, K., Weil, R.J.
Novel anti-filamin-A antibody detects a secreted variant of filamin-A in plasma from patients with breast carcinoma and high-grade astrocytoma.
Cancer Sci, 100, 1748-1756 (2009)
Hanyu, A., Kojima, K., Hatake, K., Nomura, K., Murayama, H., Ishikawa, Y., Miyata, S., Ushijima, M., Matsuura, M., Ogata, E., Miyazawa, K., Imamura, T.
Functional in vivo optical imaging of tumor angiogenesis, growth, and metastasis prevented by administration of anti-human VEGF antibody in xenograft model of human fibrosarcoma HT1080 cells.
Cancer Sci, 100, 2085-2092 (2009)
Hiki, N., Fukunaga, T., Yamaguchi, T., Ogura, T., Miyata, S., Tokunaga, M., Ohyama, S., Sano, T.
Increased fat content and body shape have little effect on the accuracy of lymph node retrieval and blood loss in laparoscopic distal gastrectomy for gastric cancer.
J Gastrointest Surg, 13, 626-633 (2009)
Hirasawa, T., Gotoda, T., Miyata, S., Kato, Y., Shimoda, T., Taniguchi, H., Fujisaki, J., Sano, T., Yamaguchi, T.
Incidence of lymph node metastasis and the feasibility of endoscopic resection for undifferentiated-type early gastric cancer.
Gastric Cancer, 12, 148-152 (2009)
Mashima, T., Sato, S., Okabe, S., Miyata, S., Matsuura, M., Sugimoto, Y., Tsuruo, T., Seimiya, H.
Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.
Cancer Sci, 100, 1556-1562 (2009)
Nakamura, Y., Migita, T., Hosoda, F., Okada, N., Gotoh, M., Arai, Y., Fukushima, M., Ohki, M., Miyata, S., Takeuchi, K., Imoto, I., Katai, H., Yamaguchi, T., Inazawa, J., Hirohashi, S., Ishikawa, Y., Shibata, T.
Kruppel-like factor 12 plays a significant role in poorly differentiated gastric cancer progression.
Int J Cancer, 125, 1859-1867 (2009)
Ninomiya, H., Hiramatsu, M., Inamura, K., Nomura, K., Okui, M., Miyoshi, T., Okumura, S., Satoh, Y., Nakagawa, K., Nishio, M., Horai, T., Miyata, S., Tsuchiya, E., Fukayama, M., Ishikawa, Y.
Correlation between morphology and EGFR mutations in lung adenocarcinomas Significance of the micropapillary pattern and the hobnail cell type.
Lung Cancer, 63, 235-240 (2009)
Osako, T., Ito, Y., Ushijima, M., Takahashi, S., Tokudome, N., Sugihara, T., Iwase, T., Matsuura, M., Hatake, K.
Predictive factors for efficacy of capecitabine in heavily pretreated patients with metastatic breast cancer.
Cancer Chemother Pharmacol, 63, 865-871 (2009)
Satoh, Y., Hoshi, R., Horai, T., Okumura, S., Nakagawa, K., Ishikawa, Y., Miyata, S.
Association of cytologic micropapillary clusters in cytology samples with lymphatic spread in clinical stage I lung adenocarcinomas.
Lung Cancer, 64, 277-281 (2009)
Takahata, M., Inoue, Y., Tsuda, H., Imoto, I., Koinuma, D., Hayashi, M., Ichikura, T., Yamori, T., Nagasaki, K., Yoshida, M., Matsuoka, M., Morishita, K., Yuki, K., Hanyu, A., Miyazawa, K., Inazawa, J., Miyazono, K., Imamura, T.
SKI and MEL1 cooperate to inhibit transforming growth factor-β signal in gastric cancer cells.
J Biol Chem, 284, 3334-3344 (2009)
Tokunaga, M., Hiki, N., Fukunaga, T., Ogura, T., Miyata, S., Yamaguchi, T.
Effect of individual fat areas on early surgical outcomes after open gastrectomy for gastric cancer.
Br J Surg, 96, 496-500 (2009)
Ueda, N., Tada, K., Miyata, S., Koizumi, M., Kuroda, Y., Iwase, T.
Identification of sentinel lymph node location based on body surface landmarks in early breast cancer patients.
Breast Cancer, 16, 219-222 (2009)
Yoshimura, K., Takeuchi, K., Nagasaki, K., Ogishima, S., Tanaka, H., Iwase, T., Akiyama, F., Kuroda, Y., Miki, Y.
Prognostic value of matrix Gla protein in breast cancer.
Mol Med Rep, 2, 549-553 (2009)

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Dohi, Y., Ikura, T., Hoshikawa, Y., Katoh, Y., Ota, K., Nakanome, A., Muto, A., Omura, S., Ohta, T., Ito, A., Yoshida, M., Noda, T., Igarashi, K.
Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.
Nat Struct Mol Biol, 15, 1246-1254 (2008)
Enomoto, Y., Ushijima, M., Miyata, S., Matuura, M., Ohtaki, M.
Inference on biological mechanisms using an integrated phenotype prediction model.
Hiroshima J Med Sci, 57, 7-15 (2008)
Inamura, K., Togashi, Y., Ninomiya, H., Shimoji, T., Noda, T., Ishikawa, Y.
HOXB2, an adverse prognostic indicator for stage I lung adenocarcinomas, promotes invasion by transcriptional regulation of metastasis-related genes in HOP-62 non-small cell lung cancer cells.
Anticancer Res, 28, 2121-2127 (2008)
Isomura, M., Oya, N., Tachiiri, S., Kaneyasu, Y., Nishimura, Y., Akimoto, T., Hareyama, M., Sugita, T., Mitsuhashi, N., Yamashita, T., Aoki, M., Sai, H., Hirokawa, Y., Sakata, K., Karasawa, K., Tomida, A., Tsuruo, T., Miki, Y., Noda, T., Hiraoka, M.
IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis.
Clin Cancer Res, 14, 6683-6689 (2008)
Komatsu, A., Nagasaki, K., Fujimori, M., Amano, J., Miki, Y.
Identification of novel deletion polymorphisms in breast cancer.
Int J Oncol, 33, 261-270 (2008)
Migita, T., Narita, T., Nomura, K., Miyagi, E., Inazuka, F., Matsuura, M., Ushijima, M., Mashima, T., Seimiya, H., Satoh, Y., Okumura, S., Nakagawa, K., Ishikawa, Y.
ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.
Cancer Res, 68, 8547-8554 (2008)
Nagasaki, K., Miki, Y.
Molecular prediction of the therapeutic response to neoadjuvant chemotherapy in breast cancer.
Breast Cancer, 15, 117-120 (2008)
Nunobe, S., Ohyama, S., Miyata, S., Matsuura, M., Hiki, N., Fukunaga, T., Seto, Y., Ushijima, M., Yamaguchi, T.
Incidence of gastric cancer in the remnant stomach after proximal gastrectomy.
Hepatogastroenterology, 55, 1855-1858 (2008)
Oku, Y., Shimoji, T., Takifuji, K., Hotta, T., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Nasu, T., Tamura, K., Matsuura, M., Miyata, S., Kato, Y., Yamaue, H., Miki, Y.
Identification of the molecular mechanisms for dedifferentiation at the invasion front of colorectal cancer by a gene expression analysis.
Clin Cancer Res, 14, 7215-7222 (2008)

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Fujisawa, H., Isomura, M., Eguchi, S., Ushijima, M., Miyata, S., Miki, Y., Matsuura, M.
Identifying haplotype block structure using an ancestor-derived model.
J Hum Genet, 52, 738-746 (2007)
Horii, R., Akiyama, F., Ito, Y., Matsuura, M., Miki, Y., Iwase, T.
Histological features of breast cancer, highly sensitive to chemotherapy.
Breast Cancer, 14, 393-400 (2007)
Inamura, K., Shimoji, T., Ninomiya, H., Hiramatsu, M., Okui, M., Satoh, Y., Okumura, S., Nakagawa, K., Noda, T., Fukayama, M., Ishikawa, Y.
A metastatic signature in entire lung adenocarcinomas irrespective of morphological heterogeneity.
Hum Pathol, 38, 702-709 (2007)
Inamura, K., Togashi, Y., Okui, M., Ninomiya, H., Hiramatsu, M., Satoh, Y., Okumura, S., Nakagawa, K., Shimoji, T., Noda, T., Ishikawa, Y.
HOXB2 as a novel prognostic indicator for stage I lung adenocarcinomas.
J Thorac Oncol, 2, 802-807 (2007)
Jin, G., Yamazaki, Y., Takuwa, M., Takahara, T., Kaneko, K., Kuwata, T., Miyata, S., Nakamura, T.
Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.
Blood, 109, 3998-4005 (2007)
Maekawa, T., Shinagawa, T., Sano, Y., Sakuma, T., Nomura, S., Nagasaki, K., Miki, Y., Saito-Ohara, F., Inazawa, J., Kohno, T., Yokota, J., Ishii, S.
Reduced levels of ATF-2 predispose mice to mammary tumors.
Mol Cell Biol, 27, 1730-1744 (2007)
Nguyen, S.T., Hasegawa, S., Tsuda, H., Tomioka, H., Ushijima, M., Noda, M., Omura, K., Miki, Y.
Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma.
Cancer Sci, 98, 740-746 (2007)
Oishi, Y., Nagasaki, K., Miyata, S., Matsuura, M., Nishimura, S., Akiyama, F., Iwai, T., Miki, Y.
Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancer.
J Hum Genet, 52, 271-279 (2007)
Shimma, S., Sugiura, Y., Hayasaka, T., Hoshikawa, Y., Noda, T., Setou, M.
MALDI-based imaging mass spectrometry revealed abnormal distribution of phospholipids in colon cancer liver metastasis.
J Chromatogr B Analyt Technol Biomed Life Sci, 855, 98-103 (2007)
Takenouchi, T., Ushijima, M., Eguchi, S.
GroupAdaBoost: Accurate prediction and selection of important genes.
IPSJ Transactions on Bioinformatics, 48, No.SIG5, 1-8 (2007)
Ushijima, M., Miyata, S., Eguchi, S., Kawakita, M., Yoshimoto, M., Iwase, T., Akiyama, F., Sakamoto, G., Nagasaki, K., Miki, Y., Noda, T., Hoshikawa, Y., Matsuura, M.
Common peak approach using mass spectrometry data sets for predicting the effects of anticancer drugs on breast cancer.
Cancer Inform, 3, 285-293 (2007)

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Nagasaki, K., Miki, Y.
Gene expression profiling of breast cancer.
Breast Cancer, 13, 2-7 (2006)
牛嶋大, 宮田敏, 松浦正明.
【クリニカルバイオインフォマティクス】 臨床情報とOMICS情報のバイオインフォマティクス的アプローチ.
生体医工学, 44, 390-396 (2006)

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