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Tetsuo Mashima

Affiliation

Education & Professional Career

1997: Ph.D. (Doctor of Pharmaceutical Sciences), The University of Tokyo
1997-1998: Institute of Molecular and Cellular Biosciences, The University of Tokyo
1998-2008: Cancer Chemotherapy Center, Japanese Foundation for Cancer Research
2008-2010: Dana-Farber Cancer Institute / Broad Institute
2010- : Present Position

Area of Research

・Prostate cancer
・Regulation of cell death
・Lipid metabolism
・Molecular cancer therapeutics

Membership

・Japanese Cancer Association
・The Japanese Association for Molecular Target Therapy of Cancer (Councilor)

Awards

2007: Incitement Award of the Japanese Cancer Association
2007: Incitement Award of the the Japanese Association for Molecular Target Therapy of Cancer

Research Projects

Why could a cell be alive or die? – This is the essential question to understand the life phenomena. Cancer is caused by the disorder of the mechanisms of survival and death. In particular, the survival mechanisms that cancer cells, but not normal cells, possess would be the cause of the uncontrolled growth as well as rational targets for therapy. From these points of view, I have worked on the defect of cell death induction mechanisms in cancer cells and have searched for factors that are involved in the mechanisms as molecular targets of cancer. Presently, we are especially focusing on prostate cancer and the survival factors that are derived from tumor-specific genetic alterations and tumor-selective environment.

• JFCR
• The Cancer Institute Hospital of JFCR
• Cancer Institute
• Cancer Chemotherapy Center
• Cancer Precision Medicine Center
• NEXT-Ganken Program
• School of Cytotechnology

• Access
• Donation
• Link concerming research
• Japanese