Pathology｜Laboratories｜Cancer Institute

Update : 2023-06-05

Overview

Department of Pathology performs research mainly on diagnosis and cancer prevention as well as make expert diagnosis for Cancer Institute Hospital. We are actively involved in the Ganken Genome Project to establish more exact pathological criteria for chemo- and radio-therapy and to advance the diagnostics of therapy effectiveness in several organ sites. Further, we are contributing to decision-making for best post-operational therapies by diagnosing more precisely surgical margins of surgical/endoscopical materials. Also, we reveal nature and malignant potential of tumors by analysis and long-term forllowup of precancerous lesions and early cancers.

Projects

Publications

2022｜2021｜2020｜2019｜2018｜2017｜2016

2022

Hayashi, K., Ono, Y., Takamatsu, M., Oba, A., Ito, H., Sato, T., Inoue, Y., Saiura, A., Takahashi, Y.: Prediction of recurrence pattern of pancreatic cancer post-pancreatic surgery using histology-based supervised machine learning algorithms: A single-center Retrospective study.
Ann. Surg. Oncol., 29 (7): 4624-4634, 2022
Ishii, S., Takamatsu, M., Ninomiya, H., Inamura, K., Horai, T., Iyoda, A., Honma, N., Hoshi, R., Sugiyama, Y., Yanagitani, N., Mun, M., Abe, H., Mikami, T., Takeuchi, K.: Machine learning-based gene alteration prediction model for primary lung cancer using cytologic images.
Cancer Cytopathol., 130 (10): 812-823, 2022
Kunieda, J., Yamashita, K., Togashi, Y., Baba, S., Sakata, S., Inamura, K., Ae, K., Matsumoto, S., Machinami, R., Kitagawa, M., Takeuchi, K.: High prevalence of TERT aberrations in myxoid liposarcoma: TERT reactivation may play a crucial role in tumorigenesis.
Cancer Sci., 113 (3): 1078-1089, 2022
Ninomiya, H., Inamura, K., Mun, M., Nishio, M., Ishikawa, Y.: Relationship between pathologic T1 categories and pathologic factors affecting prognosis in pulmonary adenocarcinoma.
JTO Clin. Res. Rep., 3 (4): 100293, 2022
Osako, T., Kurisaki-Arakawa, A., Dobashi, A., Togashi, Y., Baba, S., Shiozawa, S., Ishigame, H., Ishige, H., Ohno, S., Ishikawa, Y., Takeuchi, K.: Distinct clinicopathologic features and possible pathogenesis of localized ALK-positive histiocytosis of the breast.
Am. J. Surg. Pathol., 46 (3): 344-352, 2022
Osako, T., Matsuura, M., Yotsumoto, D., Takayama, S., Kaneko, K., Takahashi, M., Shimazu, K., Yoshidome, K., Kuraoka, K., Itakura, M., Tani, M., Ishikawa, T., Ohi, Y., Kinoshita, T., Sato, N., Tsujimoto, M., Nakamura, S., Tsuda, H., Noguchi, S., Akiyama, F.: A prediction model for early systemic recurrence in breast cancer using a molecular diagnostic analysis of sentinel lymph nodes: A large-scale, multicenter cohort study.
Cancer, 128 (10): 1913-1920, 2022
Shigematsu, Y., Amori, G., Kanda, H., Takahashi, Y., Takazawa, Y., Takeuchi, K., Inamura, K.: Decreased ARG1 expression as an adverse prognostic phenotype in non-alcoholic non-virus-related hepatocellular carcinoma.
Virchows Arch., 481 (2): 253-263, 2022
Shigematsu, Y., Nakano, K., Uchibori, K., Inamura, K.: EGFR-mutated pulmonary choriocarcinoma combined with adenocarcinoma. J. Thorac. Oncol.: in press, 2022
Shigematsu, Y., Kanda, H., Amori, G., Takahashi, Y., Takazawa, Y., Inamura, K.: Nonalcoholic non-virus-related hepatocellular carcinoma arising from nonsteatotic liver: Clinical and pathological features.
Medicine (Baltimore), 101 (5): e28746, 2022
Takamatsu, M., Yamamoto, N., Kawachi, H., Nakano, K., Saito, S., Fukunaga, Y., Takeuchi, K.: Prediction of lymph node metastasis in early colorectal cancer based on histologic images by artificial intelligence.
Sci. Rep., 12 (1): 2963, 2022
Takeuchi, K.: Idiopathic plasmacytic lymphadenopathy: A conceptual history along with a translation of the original Japanese article published in 1980.
J. Clin. Exp. Hematop., 62 (2): 79-84, 2022
Tsuyama, N., Noguchi, M., Asaka, R., Sakata, S., Baba, S., Izumi, H., Takeuchi, K.: Hodgkinoid histiocytosis: An atypical nodal CD30 and S100-positive histiocytosis with eosinophilia.
Histopathology, 81 (3): 371-379, 2022
Yamashita, K., Funauchi, Y., Hayakawa, K., Ae, K., Matsumoto, S., Ikuta, K., Nishida, Y., Ueno, T., Shimoyama, Y., Hiruta, N., Machinami, R., Kawachi, H., Takeuchi, K.: S100-negative epithelioid malignant peripheral nerve sheath tumor with possible perineurial differentiation.
Virchows Arch., 480 (6): 1269-1275, 2022
Inamura, K., Hamada, T., Bullman, S., Ugai, T., Yachida, S., Ogino, S.: Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science.
Gut, 71 (10): 2107-2122, 2022
Tonooka, A., Ohashi, R.: Current trends of anti-cancer molecular targeted therapies: a narrative review focusing on renal complications and their histological features.
J. Nippon Med. Sch., 89 (2): 128-138, 2022
Osako, T., Matsuura, M., Tsuda, H., Noguchi, S.: Reply to "Survival analysis in a prediction model for early systemic recurrence in breast cancer".
Cancer, 128 (20): 3745-3746, 2022
Sugawara, E., Koyama, K., Inamura, K.: Molecular characterization of upper tract urothelial carcinoma for precision therapeutics and non-invasive diagnostics.
Curr. Genomics, 23 (1): 2-4, 2022

2021

Akiya, M., Osako, T., Morizono, H., Furuta, N., Kikuchi, M., Ueno, T., Ohno, S., Takeuchi, K.: Myofibroblastoma of the breast showing rare palisaded morphology and uncommon desmin- and CD34-negative immunophenotype: A case report. Pathol. Int., 71 (8): 548-555, 2021
Amori, G., Sugawara, E., Shigematsu, Y., Akiya, M., Kunieda, J., Yuasa, T., Yamamoto, S., Yonese, J., Takeuchi, K., Inamura, K.: Tumor B7-H3 expression in diagnostic biopsy specimens and survival in patients with metastatic prostate cancer. Prostate Cancer Prostatic Dis., 24 (3): 767-774, 2021
Horii, R., Nitta, H., Nojima, M., Maruyama, R., Ueno, T., Ito, Y., Ohno, S., Banks, P., Kanda, H., Akiyama, F.: Predictive significance of HER2 intratumoral heterogeneity, determined by simultaneous gene and protein analysis, for resistance to trastuzumab-based treatments for HER2-positive breast cancer. Virchows Arch., 479 (1): 13-21, 2021
Inamura, K.: Adjuvant chemotherapy in patients with early-stage non-small cell lung cancer. JAMA Oncol., 7 (4): 637-638, 2021
Maeshima, Y., Osako, T., Morizono, H., Yunokawa, M., Miyagi, Y., Kikuchi, M., Ueno, T., Ohno, S., Akiyama, F.: Metastatic ovarian cancer spreading into mammary ducts mimicking an in situ component of primary breast cancer: A case report. J. Med. Case Rep., 15 (1): 78, 2021
Saito, R., Ninomiya, H., Okumura, S., Mun, M., Sasano, H., Ishikawa, Y.: Novel histologic classification of small tumor cell nests for lung adenocarcinoma with prognostic and etiological significance: Small solid nests and pure micropapillary nests. Am. J. Surg. Pathol., 45 (5): 604-615, 2021
Sugiura, Y., Machinami, R., Matsumoto, S., Kanda, H., Ae, K., Takazawa, Y., Takeuchi, K.: Prognostic value of CD34 expression status in patients with myxofibrosarcomas and undifferentiated pleomorphic sarcomas. Sci. Rep., 11 (1): 15494, 2021
Tsugeno, Y., Kawachi, H., Kirimura, S., Hirota, Y., Shintaku, H., Ito, T., Kikuchi, A., Ohtsuka, K., Akashi, T., Kitagawa, M.: Adenocarcinoma arising in the multiple heterotopic submucosal glands of the intestine in a Satoyoshi syndrome patient: A case report. Pathol. Int., 71 (2): 147-154, 2021
Yamashita, K., Kohashi, K., Yamada, Y., Akatsuka, S., Ikuta, K., Nishida, Y., Toyokuni, S., Oda, Y.: Prognostic significance of the MDM2/HMGA2 ratio and histological tumor grade in dedifferentiated liposarcoma. Genes Chromosomes Cancer, 60 (1): 26-37, 2021
Inamura, K.: Gut microbiota contributes towards immunomodulation against cancer: New frontiers in precision cancer therapeutics. Semin. Cancer Biol., 70: 11-23, 2021
Osako, T.: How can we better distinguish metastatic tumors from primary tumors in the breast? Expert Rev. Anticancer Ther., 21 (9): 913-916, 2021

2020

Ebina, A., Togashi, Y., Baba, S., Sato, Y., Sakata, S., Ishikawa, M., Mitani, H., Takeuchi, K. and Sugitani, I. (2020): TERT promoter mutation and extent of thyroidectomy in patients with 1-4 cm intrathyroidal papillary carcinoma. Cancers (Basel), 12: 2115
Horii, R., Tsuda, H., Masuda, S., Sugita, H., Togashi, K., Ohno, S. and Akiyama, F. (2020): Performance analysis of the anti-Ki67 antibody clone 30-9 for immunohistochemical staining of breast cancer. Breast Cancer, 27: 1058-1064
Inamura, K. (2020): Ethical Considerations about Genomic Medicine Implementation: Lessons Learned from the eMERGE III Study. Journal of personalized medicine, 10: E195
Inamura, K. (2020): Gut microbiota contributes towards immunomodulation against cancer: New frontiers in precision cancer therapeutics. Semin. Cancer Biol.: in press
Inamura, K. (2020): Roles of microbiota in response to cancer immunotherapy. Semin. Cancer Biol., 65: 164-175
Ishii, S., Ito, T., Yamada, M., Yamazaki, N., Ikebata, K., Fujiyama, J., Furuta, N., Komatsu, K., Takeuchi, K., Sugiyama, Y. and Takazawa, Y. (2020): Characteristic cytological findings of lobular endocervical glandular hyperplasia associated with adenocarcinoma of the uterine cervix. Acta Cytol., 64: 556-562
Luangxay, T., Osako, T., Yonekura, R., Sugiura, Y., Kikuchi, M., Gomi, N., Ueno, T., Ohno, S., Machinami, R., Takeuchi, K. and Akiyama, F. (2020): Giant cell tumor of soft tissue of the breast: Case report with H3F3A mutation analysis and review of the literature. Pathol. Res. Pract., 216: 152750
Naito, K., Shigematsu, Y., Fujiwara, Y., Inamura, K., Togashi, Y., Inoue, Y., Takazawa, Y., Kanda, H. and Matsueda, K. (2020): Identification of a specific ultrasonographic finding for differentiating hepatic angiomyolipoma from hepatocellular carcinoma. Clin. Imag., 59: 104-108
Nakashima, Y., Inamura, K., Ninomiya, H., Okumura, S., Mun, M., Kirimura, S., Kobayashi, M., Okubo, K. and Ishikawa, Y. (2020): Frequent expression of conventional endothelial markers in pleural mesothelioma: Usefulness of claudin-5 as well as combined traditional markers to distinguish mesothelioma from angiosarcoma. Lung Cancer, 148: 20-27
Omi, M., Tonooka, A., Chiba, T., Tanaka, Y., Fusegi, A., Aoki, Y., Nomura, H., Kanao, H. and Takazawa, Y. (2020): Immunohistochemical markers and the clinical course of adenosarcoma: a series of seven cases. Diagn. Pathol., 15: 119
Osako, T., Lee, H., Turashvili, G., Chiu, D. Y., McKinney, S., Joosten, S. E. P., Wilkinson, D. S., Nielsen, T. O., Zwart, W., Emerman, J. T., Eaves, C. J., Caldas, C. and Aparicio, S. (2020): Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects. Nature Cancer, 1: 518-532
Sakamoto, K. and Takeuchi, K. (2020): Cytogenetics of blastic plasmacytoid dendritic cell neoplasm: Chromosomal rearrangements and DNA copy-number alterations. Hematol. Oncol .Clin .North Am., 34: 523-538
Shigematsu, Y., Yamashita, K., Takamatsu, M., Tanizawa, T., Togashi, Y., Nakajima, T., Chino, A., Kawachi, H. and Takeuchi, K. (2020): Primary intramucosal synovial sarcoma of the sigmoid colon in a patient with a germline mutation in the MSH2 gene: A case report. Pathol. Int., 70: 1015-1019
Tsugeno, Y., Nakano, K., Nakajima, T., Namikawa, K., Takamatsu, M., Yamamoto, N., Fujisaki, J., Nunobe, S., Kitagawa, M., Takeuchi, K. and Kawachi, H. (2020): Histopathologic analysis of signet-ring cell carcinoma in situ in patients with hereditary diffuse gastric cancer. Am. J. Surg. Pathol., 44: 1204-1212
Wakejima, R., Inamura, K., Ninomiya, H., Nagano, H., Mun, M., Okumura, S., Okubo, K. and Ishikawa, Y. (2020): Mucinous lung adenocarcinoma, particularly referring to EGFR-mutated mucinous adenocarcinoma. Pathol. Int., 70: 72-83
Yamamoto, T., Gulanbar, A., Hayashi, K., Kohno, A., Komai, Y., Yonese, J., Matsueda, K. and Inamura, K. (2020): Is hypervascular papillary renal cell carcinoma present? Abdom. Radiol.: in press
Yoshimizu, S., Kawachi, H., Yamamoto, Y., Nakano, K., Horiuchi, Y., Ishiyama, A., Tsuchida, T., Yoshio, T., Hirasawa, T., Ito, H. and Fujisaki, J. (2020): Clinicopathological features and risk factors for lymph node metastasis in early-stage non-ampullary duodenal adenocarcinoma. J. Gastroenterol., 55: 754-762

2019

Chang, K. C., Yu-Yun Lee, J., Sakamoto, K., Baba, S. and Takeuchi, K. (2019): Blastic plasmacytoid dendritic cell neoplasm with immunoblastoid morphology and MYC rearrangement and overexpression. Pathology, 51: 100-102
Hashimoto, H., Tsugeno, Y., Sugita, K. and Inamura, K. (2019): Mesenchymal tumors of the lung: diagnostic pathology, molecular pathogenesis, and identified biomarkers. J. Thorac. Dis., 11: S9-S24
Hashimoto, H., Usui, G., Tsugeno, Y., Sugita, K., Amori, G., Morikawa, T. and Inamura, K. (2019): Cerebral thromboembolism after lobectomy for lung cancer: Pathological diagnosis and mechanism of thrombus formation. Cancers (Basel), 11: E-488
Inamura, K., Amori, G., Yuasa, T., Yamamoto, S., Yonese, J. and Ishikawa, Y. (2019): Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma. Cancer Manag. Res., 11: 7021-7030
Ishioka, M., Hirasawa, T., Kawachi, H., Nakano, K., Kunieda, J., Yoshimizu, S., Horiuchi, Y., Ishiyama, A., Yoshio, T., Tsuchida, T. and Fujisaki, J. (2019): Enterochromaffin-like cell neuroendocrine tumor associated with parietal cell dysfunction. Gastrointest. Endosc., 90: 841-845.e841
Kawachi, H. (2019): Histopathological diagnosis of ulcerative colitis-associated neoplasia. Dig. Endosc., 31 Suppl 1: 31-35
Kobayashi, M., Kawachi, H., Pasternak, S., Delgado, C., Pinto, P., Ito, T., Karelovic, S., Carrasco, H., Tanaka, K., Okada, T., Odagaki, T., Zarate, A. J., Ponce, A., Kronberg, U., Lopez-Kostner, F., Tsubaki, M., Kawano, T. and Eishi, Y. (2019): Histopathologic study from a colorectal cancer screening in Chile: results from the first 2 years of an international collaboration between Chile and Japan. Eur. J. Cancer Prev., 28: 245-253
Matsue, K., Abe, Y., Narita, K., Kobayashi, H., Kitadate, A., Takeuchi, M., Miura, D. and Takeuchi, K. (2019): Diagnosis of intravascular large B-cell lymphoma: novel insights into clinicopathological features from 42 patients at a single institution over 20 years. Br. J. Haematol., 187: 328-336
Osumi, H., Kawachi, H., Murai, K., Kusafuka, K., Inoue, S., Kitamura, M., Yoshio, T., Kakusima, N., Ishihara, R., Ono, H., Yamamoto, N., Sugino, T., Nakatsuka, S., Ida, S., Nunobe, S., Bando, E., Omori, T., Takeuchi, K. and Fujisaki, J. (2019): Risk stratification for lymph node metastasis using Epstein-Barr virus status in submucosal invasive (pT1) gastric cancer without lymphovascular invasion: a multicenter observational study. Gastric Cancer, 22: 1176-1182
Osumi, H., Kawachi, H., Yoshio, T., Ida, S., Yamamoto, N., Horiuchi, Y., Ishiyama, A., Hirasawa, T., Tsuchida, T., Hiki, N., Takeuchi, K. and Fujisaki, J. (2019): Epstein-Barr virus status is a promising biomarker for endoscopic resection in early gastric cancer: proposal of a novel therapeutic strategy. J. Gastroenterol., 54: 774-783
Takamatsu, M., Kawachi, H., Yamamoto, N., Kobayashi, M., Toyama, Y., Maekawa, T., Chino, A., Saito, S., Ueno, M., Takazawa, Y. and Ishikawa, Y. (2019) Immunohistochemical evaluation of tumor budding for stratifying: T1 colorectal cancer: optimal cut-off value and a novel computer-assisted semiautomatic method. Mod. Pathol., 32: 675-683
Takamatsu, M., Yamamoto, N., Kawachi, H., Chino, A., Saito, S., Ueno, M., Ishikawa, Y., Takazawa, Y. and Takeuchi, K. (2019): Prediction of early colorectal cancer metastasis by machine learning using digital slide images. Comput. Methods Programs Biomed., 178: 155-161
Takeuchi, K. (2019): Discovery stories of RET fusions in lung cancer: A mini-review. Front. Physiol., 10: 216
Tsuyama, N., Yokoyama, M., Fujisaki, J., Oguchi, M., Terui, Y. and Takeuchi, K. (2019): Villous colonization (glove balloon sign): A histopathological diagnostic marker for follicular lymphomas with duodenal involvement including duodenal-type follicular lymphoma. Pathol. Int., 69: 48-50
Yamamoto, T., Koizumi, M., Kohno, A., Numao, N. and Inamura, K. (2019): A case report on 111In chloride bone marrow scintigraphy in management of adrenal myelolipoma. Medicine (Baltimore), 98: e14625
Yonekura, R., Horii, R., Iwase, T., Gomi, N., Kitagawa, M., Akiyama, F. and Ohno, S. (2019): A diagnostic strategy for breast calcifications based on a long-term follow-up of 615 lesions. Jpn. J. Radiol., 37: 237-244
Yonekura R, Osako T, Iwase T, Ogiya A, Ueno T, Kitagawa M, et al.: Prognostic impact and possible pathogenesis of lymph node metastasis in ductal carcinoma in situ of the breast. Breast Cancer Res Treat. 2019;174(1):103-11.

2018

Dobashi, A., Togashi, Y., Tanaka, N., Yokoyama, M., Tsuyama, N., Baba, S., Mori, S., Hatake, K., Yamaguchi, T., Noda, T. and Takeuchi, K. (2018): TP53 and OSBPL10 alterations in diffuse large B-cell lymphoma: prognostic markers identified via exome analysis of cases with extreme prognosis. Oncotarget, 9: 19555-19568
Inamura, K. (2018): Bladder cancer: New insights into its molecular pathology. Cancers (Basel), 10: pii: E100
Inamura, K. (2018): Clinicopathological characteristics and mutations driving development of early lung Adenocarcinoma: tumor initiation and progression. Int. J. Mol. Sci., 19: pii: E1259
Inamura, K. (2018): Prostatic cancers: understanding their molecular pathology and the 2016 WHO classification. Oncotarget, 9: 14723-14737
Inamura, K. (2018): Update on immunohistochemistry for thedDiagnosis of lung cancer. Cancers (Basel), 10: pii: E72
Inamura, K., Shigematsu, Y., Ninomiya, H., Nakashima, Y., Kobayashi, M., Saito, H., Takahashi, K., Futaya, E., Okumura, S., Ishikawa, Y. and Kanda, H. (2018): CSF1R-expressing tumor-associated macrophages, smoking and survival in lung adenocarcinoma: Analyses using quantitative phosphor-integrated dot staining. Cancers (Basel), 10: E252
Inamura, K., Takazawa, Y., Inoue, Y., Yokouchi, Y., Kobayashi, M., Saiura, A., Shibutani, T. and Ishikawa, Y. (2018): Tumor B7-H3 (CD276) expression and survival in pancreatic cancer. J. Clin. Med., 7: 172
Inoue, H., Horii, R., Ito, Y., Iwase, T., Ohno, S. and Akiyama, F. (2018): Tumor-infiltrating lymphocytes affect the efficacy of trastuzumab-based treatment in human epidermal growth factor receptor 2-positive breast cancer. Breast Cancer, 25: 268-274
Kanda, H., Furuta, N., Takazawa, Y., Furuta, R., Ae, K., Sugiyama, Y. and Ishikawa, Y. (2018): Cytological findings of gastrointestinal stromal tumor-derived bone metastasis. Acta Cytol., 62: 430-435
Noma, D., Inamura, K., Matsuura, Y., Hirata, Y., Nakajima, T., Yamazaki, H., Hirai, Y., Ichinose, J., Nakao, M., Ninomiya, H., Mun, M., Nakagawa, K., Masuda, M., Ishikawa, Y. and Okumura, S. (2018): Prognostic effect of lymphovascular invasion on TNM staging in stage I non-small-cell lung cancer. Clin. Lung Cancer, 19: e109-e122
Sakamoto, K., Katayama, R., Asaka, R., Sakata, S., Baba, S., Nakasone, H., Koike, S., Tsuyama, N., Dobashi, A., Sasaki, M., Ichinohasama, R., Takakuwa, E., Yamazaki, R., Takizawa, J., Maeda, T., Narita, M., Izutsu, K., Kanda, Y., Ohshima, K. and Takeuchi, K. (2018): Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm: association with immunoblastoid cytomorphology, MYC expression, and drug response. Leukemia, 32: 2590-2603
Shigematsu, Y. and Inamura, K. (2018): Gut microbiome: a key player in cancer immunotherapy. Hepatobiliary Surg. Nutr., 7: 479-480
Shigematsu, Y., Inamura, K., Mise, Y., Saiura, A., Rehnberg, E., Yamamoto, N., Ishikawa, Y., Takahashi, S. and Kanda, H. (2018): CDX2 expression is concordant between primary colorectal cancer lesions and corresponding liver metastases independent of chemotherapy: a single-center retrospective study in Japan. Oncotarget, 9: 17056-17065
Shigematsu, Y., Inamura, K., Yamamoto, N., Mise, Y., Saiura, A., Ishikawa, Y., Takahashi, S. and Kanda, H. (2018): Impact of CDX2 expression status on the survival of patients after curative resection for colorectal cancer liver metastasis. BMC Cancer, 18: 980
Shigematsu, Y., Kanda, H., Nagasaki, T., Inoue, Y. and Takahashi, S. (2018): Hepatic eosinophilic abscesses associated with sigmoid colon cancer Intern. Med., 57: 1405-1409
Subat, S., Inamura, K., Ninomiya, H., Nagano, H., Okumura, S. and Ishikawa, Y. (2018): Unique MicroRNA and mRNA Interactions in EGFR-Mutated Lung Adenocarcinoma. J. Clin. Med., 7: 419
Takamatsu, M., Sato, Y., Muto, M., Nagano, H., Ninomiya, H., Sakakibara, R., Baba, S., Sakata, S., Takeuchi, K., Okumura, S. and Ishikawa, Y. (2018): Hyalinizing clear cell carcinoma of the bronchial glands: presentation of three cases and pathological comparisons with salivary gland counterparts and bronchial mucoepidermoid carcinomas. Mod. Pathol., 31: 923-933
Togashi, Y., Dobashi, A., Sakata, S., Sato, Y., Baba, S., Seto, A., Mitani, H., Kawabata, K. and Takeuchi, K. (2018): MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts. Mod. Pathol., 31: 934-946
Tsuyama, N., Asaka, R., Dobashi, A., Baba, S., Mishima, Y., Ueda, K., Oguchi, M., Tsuji, H., Hatake, K. and Takeuchi, K. (2018): Epstein-Barr virus-negative extranodal “true” natural killer-cell lymphoma harbouring a KDM6A mutation. Hematol. Oncol., 36: 328-335
Yamazaki, K., Horii, R., Iwase, T., Ueno, T., Ohno, S. and Akiyama, F. (2018): Ductal carcinoma in situ manageable by active surveillance. Ann. Breast Cancer Res., 3: 1-4

2017

Inamura, K. (2017): Diagnostic and therapeutic potential of microRNAs in lung cancer. Cancers (Basel), 9: pii: E49.
Inamura, K. (2017): Lung cancer: Understanding its molecular pathology and the 2015 WHO classification. Front. Oncol., 7: 193
Inamura, K. (2017): Major tumor suppressor and oncogenic non-coding RNAs: Clinical relevance in lung cancer. Cells, 6: 12
Inamura, K. (2017): Renal cell tumors: Understanding their molecular pathological epidemiology and the 2016 WHO classification. Int. J. Mol. Sci., 18: pii: E2195
Inamura, K. (2017): Translocation renal cell carcinoma: An update on clinicopathological and molecular features. Cancers (Basel), 9: pii: E111
Inamura, K., Kobayashi, M., Nagano, H., Sugiura, Y., Ogawa, M., Masuda, H., Yonese, J. and Ishikawa, Y. (2017): A novel fusion of HNRNPA1-ALK in inflammatory myofibroblastic tumor of urinary bladder. Hum. Pathol., 69: 96-100
Inamura, K., Yokouchi, Y., Kobayashi, M., Ninomiya, H., Sakakibara, R., Nishio, M., Okumura, S. and Ishikawa, Y. (2017): Relationship of tumor PD-L1 (CD274) expression with lower mortality in lung high-grade neuroendocrine tumor. Cancer Med., 6: 2347-2356
Inamura, K., Yokouchi, Y., Kobayashi, M., Ninomiya, H., Sakakibara, R., Subat, S., Nagano, H., Nomura, K., Okumura, S., Sibutani, T. and Ishikawa, Y. (2017): Association of tumor TROP2 expression with prognosis varies among lung cancer subtypes. Oncotarget, 8: 28725-28735
Inamura, K., Yokouchi, Y., Kobayashi, M., Sakakibara, R., Ninomiya, H., Subat, S., Nagano, H., Nomura, K., Okumura, S., Shibutani, T. and Ishikawa, Y. (2017) T: umor B7-H3 (CD276) expression and smoking history in relation to lung adenocarcinoma prognosis. Lung Cancer, 103: 44-51
Muto, M., Inamura, K., Ozawa, N., Endo, T., Masuda, H., Yonese, J. and Ishikawa, Y. (2017): Skene's gland adenocarcinoma with intestinal differentiation: A case report and literature review. Pathol. Int., 67: 575-579
Osako, T., Iwase, T., Ushijima, M., Yonekura, R., Ohno, S. and Akiyama, F. (2017): A new molecular-based lymph node staging classification determines the prognosis of breast cancer patients. Br. J. Cancer., 117: 1470-1477
Sakakibara, R., Inamura, K., Tambo, Y., Ninomiya, H., Kitazono, S., Yanagitani, N., Horiike, A., Ohyanagi, F., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Inase, N., Nishio, M., Motoi, N. and Ishikawa, Y. (2017): EBUS-TBNA as a promising method for the evaluation of tumor PD-L1 expression in lung cancer. Clin. Lung Cancer, 18: 527-534
Shigematsu, Y., Kanda, H., Konishi, T., Takazawa, Y., Inoue, Y., Muto, T., Ishikawa, Y. and Takahashi, S. (2017): Recurrence 30 years after surgical resection of localized rectal neuroendocrine tumor. Intern. Med., 56: 1521-1525
Tsuyama, N., Ennishi, D., Yokoyama, M., Baba, S., Asaka, R., Mishima, Y., Terui, Y., Hatake, K. and Takeuchi, K. (2017): Clinical and prognostic significance of aberrant T-cell marker expression in 225 cases of de novo diffuse large B-cell lymphoma and 276 cases of other B-cell lymphomas. Oncotarget, 8: 33487-33500
Tsuyama, N., Sakamoto, K., Sakata, S., Dobashi, A. and Takeuchi, K. (2017): Anaplastic large cell lymphoma: pathology, genetics, and clinical aspects. J. Clin. Exp. Hematop., 57: 120-142
Tsuyama, N., Sakata, S., Baba, S., Mishima, Y., Nishimura, N., Ueda, K., Yokoyama, M., Terui, Y., Hatake, K., Kitagawa, M., Ishizuka, N., Tomita, N. and Takeuchi, K. (2017): BCL2 expression in DLBCL: reappraisal of immunohistochemistry with new criteria for therapeutic biomarker evaluation. Blood, 130: 489-500

2016

Dobashi, A., Tsuyama, N., Asaka, R., Togashi, Y., Ueda, K., Sakata, S., Baba, S., Sakamoto, K., Hatake, K. and Takeuchi, K. (2016): Frequent BCOR aberrations in extranodal NK/T-Cell lymphoma, nasal type. Genes Chromosomes Cancer, 55: 460-471
Horii, R. and Akiyama, F. (2016): Histological assessment of therapeutic response in breast cancer. Breast Cancer, 23: 540-545
Horii, R., Honma, N., Ogiya, A., Kozuka, Y., Yoshida, K., Yoshida, M., Horiguchi, S. I., Ito, Y. and Mukai, H. (2016): The Japanese Breast Cancer Society clinical practice guidelines for pathological diagnosis of breast cancer, 2015 edition. Breast Cancer, 23: 391-399
Inamura, K. and Ishikawa, Y. (2016): MicroRNA In lung cancer: Novel biomarkers and potential tools for treatment. J. Clin. Med., 5: pii: E36
Inamura, K., Yokouchi, Y., Sakakibara, R., Kobayashi, M., Subat, S., Ninomiya, H., Nagano, H., Nomura, K., Okumura, S. and Ishikawa, Y. (2016): Relationship of tumor PD-L1 expression with EGFR wild-type status and poor prognosis in lung adenocarcinoma. Jpn. J. Clin. Oncol., 46: 935-941
Kanda, H., Furuta, R., Motoi, N., Suzuki, N., Furuta, N., Komatsu, K., Sugiyama, Y., Saiura, A., Sugitani, M. and Ishikawa, Y. (2016): Touch cytology smear of an inflammatory hepatocellular adenoma displaying an unusual pattern: A case report. Diagn. Cytopathol., 44: 1074-1077
Kobayashi, K., Horii, R., Ito, Y., Ohno, S., Iwase, T. and Akiyama, F. (2016): Prognostic significance of histological therapeutic effect in preoperative chemotherapy for breast cancer. Pathol. Int., 66: 8-14
Nakagawa, T., Horii, R., Ito, Y., Iwase, T. and Akiyama, F. (2016): Development of an easy method to test for HER2 in breast cancer using dual-color in situ hybridization. Breast Cancer, 23: 78-84
Noma, D., Inamura, K., Mun, M., Terauchi, T., Matsuura, Y., Nakao, M., Ninomiya, H., Nakagawa, K., Masuda, M., Okumura, S. and Ishikawa, Y. (2016): Thymic oncocytic carcinoid with a markedly elevated level of maximum SUV. Pathol. Int., 66: 593-595
Sakamoto, K., Nakasone, H., Togashi, Y., Sakata, S., Tsuyama, N., Baba, S., Dobashi, A., Asaka, R., Tsai, C. C., Chuang, S. S., Izutsu, K., Kanda, Y. and Takeuchi, K. (2016): ALK-positive large B-cell lymphoma: identification of EML4-ALK and a review of the literature focusing on the ALK immunohistochemical staining pattern. Int. J. Hematol., 103: 399-408
Shigematsu, Y., Araki, K., Horii, R., Akiyama, F., Takahashi, S., Ohno, S. and Itoh, Y. (2016): Aggressive recurrence of early breast invasive ductal carcinoma with gastric metastasis during adjuvant hormonal therapy. Case Rep. Clin. Pathol., 3: 1-6
Shigematsu, Y., Matsuura, M., Nishimura, N., Tsuyama, N., Takeuchi, K., Terui, Y., Takeshima, N. and Hatake, K. (2016): Intravascular large B-cell lymphoma of bilateral ovaries and the uterus in an asymptomatic patient with a t(11;22)(q23;q11) constitutional translocation. Intern. Med., 55: 3169-3174
Takeuchi, K., Togashi, Y., Kamihara, Y., Fukuyama, T., Yoshioka, H., Inoue, A., Katsuki, H., Kiura, K., Nakagawa, K., Seto, T., Maemondo, M., Hida, T., Harada, M., Ohe, Y., Nogami, N., Yamamoto, N., Nishio, M. and Tamura, T. (2016): Prospective and clinical validation of ALK immunohistochemistry: Results from the phase I/II study of alectinib for ALK-positive lung cancer (AF-001JP study). Ann. Oncol., 27: 185-192