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最近の論文

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2017年

2017年9月26日
Osako, T., Iwase, T., Ushijima, M., Yonekura, R., Ohno, S. and Akiyama, F.
A new molecular-based lymph node staging classification determines the prognosis of breast cancer patients.
Br. J. Cancer., in press (2017)
2017年8月29日
Takemoto, A., Miyata, K. and Fujita, N.
Platelet-activating factor podoplanin: from discovery to drug development.
Cancer and metastasis reviews, 36, 225-234 (2017)
2017年8月22日
Katayama, R.
Therapeutic strategies and mechanisms of drug resistance in Anaplastic Lymphoma Kinase (ALK)-rearranged lung cancer.
Pharmacol. Ther., 117, 1-8 (2017)
2017年7月28日
Fuse, J. M., Okada, K., Oh-hara, T., Ogura, H., Fujita, N. and Katayama, R.
Mechanisms of resistance to NTRK inhibitors and therapeutic strategies in NTRK1-rearranged cancers.
Mol. Cancer Ther., 16, 2130-2143 (2017)
2017年7月19日
Ogura, H., Nagatake-Kobayashi, Y., Adachi, J., Tomonaga, T., Fujita, N. and Katayama, R.
TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
Sci. Rep., 7, 5519 (2017)
2017年7月13日
N. Tsuyama, R. Asaka, A. Dobashi, S. Baba, Y. Mishima, K. Ueda, M. Oguchi, H. Tsuji, K. hatake and K. Takeuchi.
Epstein-Barr virus-negative extranodal “true” natural killer-cell lymphoma harbouring a KDM6A mutation.
Hematol. Oncol., in press (2017)
2017年6月23日
Miyata, K., Takemoto, A., Okumura, S., Nishio, M. and Fujita, N.
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation.
Sci. Rep., 7, 4059 (2017)
2017年6月19日
Nakamura, T., Okabe, S., Yoshida, H., Iida, K., Ma, Y., Sasaki, S., Yamori, T., Shin-Ya, K., Nakano, I., Nagasawa, K. and Seimiya, H.
Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.
Sci Rep, 7, 3605 (2017)

2017年6月7日
Takasugi, M., Okada, R., Takahashi, A., Chen, D. V., Watanabe, S. and Hara, E.
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Nat. Commun., doi:10.1038/ncomms15728 (2017)
2017年5月25日
Mashima, T., Taneda, Y., Jang, M. K., Mizutani, A., Muramatsu, Y., Yoshida, H., Sato, A., Tanaka, N., Sugimoto, Y. and Seimiya, H.
mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
Oncotarget, doi: 10.18632/oncotarget.18146 (2017)
2017年5月25日
Migita, T., Ueda, A., Ohishi, T., Hatano, M., Seimiya, H., Horiguchi, S., Koga, F. and Shibasaki, F.
Epithelial-mesenchymal transition promotes SOX2 and NANOG expression in bladder cancer.
Lab. Invest., 97, 567-576 (2017)
2017年5月19日
N. Tsuyama, S. Sakata, S. Baba, Y. Mishima, N. Nishimura, K. Ueda, M. Yokoyama, Y. Terui, K. Hatake, M. Kitagawa, N. Ishizuka, N. Tomita and K. Takeuchi.
BCL2 expression in DLBCL: reappraisal of immunohistochemistry with new criteria for therapeutic biomarker evaluation.
Blood, in press (2017)
2017年5月17日
Takahashi, A., Okada, R., Nagao, K., Kawamata, Y., Hanyu, A., Yoshimoto, S., Takasugi, M., Watanabe, S., Kanemaki, M., Obuse, C. and Hara, E.
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
Nat. Commun., 8, 15287 (2017)
2017年4月21日
Yoshimoto, T., Motoi, N., Yamamoto, N., Nagano, H., Ushijima, M., Matsuura, M., Okumura, S., Yamaguchi, T., Fukayama, M. and Ishikawa, Y.
Pulmonary carcinoids and low-grade gastrointestinal neuroendocrine tumors show common nicroRNA expression profiles, different from adenocarcinomas and small cell carcinomas.
Neuroendocrinology, in press (2017)
2017年4月14日
T. Yoshimoto, M. Tanaka, M. Homme, Y. Yamazaki, Y. Takazawa, C. R. Antonescu and T. Nakamura.
CIC-DUX4 induces small round cell sarcomas distinct from Ewing sarcoma.
Cancer research, in press, (2017)
2017年3月27日
Tsuyama, N., Ennishi, D., Yokoyama, M., Baba, S., Asaka, R., Mishima, Y., Terui, Y., Hatake, K. and Takeuchi, K.
Clinical and prognostic significance of aberrant T-cell marker expression in 225 cases of de novo diffuse large B-cell lymphoma and 276 cases of other B-cell lymphomas.
Oncotarget, 16532 (2017)
2017年3月17日
Tamura, T., Kiura, K., Seto, T., Nakagawa, K., Maemondo, M., Inoue, A., Hida, T., Yoshioka, H., Harada, M., Ohe, Y., Nogami, N., Murakami, H., Kuriki, H., Shimada, T., Tanaka, T., Takeuchi, K. and Nishio, M.
Three-year follow-up of an alectinib phase I/II study in ALK-positive non-small-cell lung cancer: AF-001JP.
J Clin Oncol, JCO2016705749 (2017)
2017年3月16日
Yoshimura, K., Inui, N., Karayama, M., Inoue, Y., Enomoto, N., Fujisawa, T., Nakamura, Y., Takeuchi, K., Sugimura, H. and Suda, T.
Successful crizotinib monotherapy in EGFR-mutant lung adenocarcinoma with acquired MET amplification after erlotinib therapy.
Respir. Med. Case Rep., 20, 160-163 (2017)
2017年3月14日
Uchibori, K., Inase, N., Araki, M., Kamada, M., Sato, S., Okuno, Y., Fujita, N. and Katayama, R.
Brigatinib combined with anti-EGFR antibody overcomes Osimertinib resistance in EGFR-mutated non-small-cell lung cancer.
Nat. Commun., 8, 14768 (2017)
2017年2月24日
Inamura, K., Yokouchi, Y., Kobayashi, M., Ninomiya, H., Sakakibara, R., Subat, S., Nagano, H., Nomura, K., Okumura, S., Sibutani, T. and Ishikawa, Y.
Association of tumor TROP2 expression with prognosis varies among lung cancer subtypes.
Oncotarget, in press (2017)
2017年2月20日
S. Takeuchi, K. Fukuda, T. Yamada, S. Arai, S. Takagi, A. Ishii, S. Ochiai, S. Iwakiri, K. Itoi, H. Uehara, H. Nishihara, N. Fujita and S. Yano.
Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation.
Cancer Science, in press (2017)
2017年2月17日
T. Ohishi, H. Yoshida, M. Katori, T. Migita, Y. Muramatsu, M. Miyake, Y. Ishikawa, A. Saiura, S. Iemura, T. Natsume and H. Seimiya.
Tankyrase-binding protein TNKS1BP1 regulates actin cytoskeleton rearrangement and cancer cell invasion.
Cancer Research, in press (2017)
2017年2月10日
Takemoto, A., Okitaka, M., Takagi, S., Takami, M., Sato, S., Nishio, M., Okumura, S. and Fujita, N.
A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis.
Sci. Rep., 7, 42186 (2017)
2017年2月10日
Tanaka, N., Mashima, T., Mizutani, A., Sato, A., Aoyama, A., Gong, B., Yoshida, H., Muramatsu, Y., Nakata, K., Matsuura, M., Katayama, R., Nagayama, S., Fujita, N., Sugimoto, Y. and Seimiya, H.
APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer.
Mol. Cancer Ther., in press (2017)
2017年2月8日
Katayama, R.
Therapeutic strategies and mechanisms of drug resistance in Anaplastic Lymphoma Kinase (ALK)-rearranged lung cancer.
Pharmacology &Therapeutics, in press (2017)

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