最終更新日 :
2017年6月13日
目次
原著論文
2017年|2016年|2015年|2014年|2012年|2011年|2010年|2009年|2008年|2007年|2006年|2005年|
2017年
- T. Z. Minas, D. Surdez, J. Tahereh, M. Tanaka, M. Howarth, H. J. Kang, J. Han, Z. Y. Han, B. Sax, B. E. Kream, S. H. Hong, F. Tirode, J. Tuckermann, J. A. Toretsky, L. Kenner, H. Kovar, S. Lee, A. Sweet-Cordero, T. Nakamura, R. Moriggi, O. Delatte and A. Uren.
- Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model.
Oncotarget, 8, 34141-34163 (2017) - M. Tanaka, M. Homme, Y. Yamazaki, R. Shimizu, Y. Takazawa and T. Nakamura.
- Modeling alveolar soft part sarcoma unveils novel mechanisms of metastasis.
Cancer Research, 77, 897-904 (2017) - T. Yoshimoto, M. Tanaka, M. Homme, Y. Yamazaki, Y. Takazawa, C. R. Antonescu and T. Nakamura.
- CIC-DUX4 induces small round cell sarcomas distinct from Ewing sarcoma.
Cancer research, in press, (2017)
2016年
- T. Hiratsuka, Y. Takei, R. Ohmori, Y. Imai, M. Ozeki, K. Tamaki, H. Haga, T. Nakamura and T. Tsuruyama.
- ZFP521 contributes to pre-B-cell lymphomagenesis through modulation of the pre-B-cell receptor signaling pathway.
Oncogene, 35, 3227-38 (2016) - K. Keeshan, P. Vieugue, S. Chaudhury, L. Rishi, C. Gaillard, L. Liang, E. Garcia, T. Nakamura, N. Omidvar and S. C. Kogan.
- Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA.
Haematologica, 101, 1228-1236 (2016) - H. Kovar, J. Amatruda, E. Brunet, S. Burdach, F. Cidre-Aranaz, E. de Alava, U. Dirksen, W. van der Ent, P. Grohar, T. G. Grunewald, L. Helman, P. Houghton, K. Iljin, E. Korsching, M. Ladanyi, E. Lawlor, S. Lessnick, J. Ludwig, P. Meltzer, M. Metzler, J. Mora, R. Moriggl, T. Nakamura, T. Papamarkou, B. Radic Sarikas, F. Redini, G. H. Richter, C. Rossig, K. Schadler, B. W. Schafer, K. Scotlandi, N. C. Sheffield, A. Shelat, E. Snaar-Jagalska, P. Sorensen, K. Stegmaier, E. Stewart, A. Sweet-Cordero, K. Szuhai, O. M. Tirado, F. Tirode, J. Toretsky, K. Tsafou, A. Uren, A. Zinovyev and O. Delattre.
- The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease.
Oncotarget, 7, 8613-24 (2016) - T. Tsuruyama, T. Hiratsuka, A. Wulamujiang and T. Nakamura.
- STAT5A modulates chemokine receptor CCR6 expression and enhances pre-B cell growth in a CCL20-dependent manner.
Journal of cellular biochemistry, 117, 2630-42 (2016) - T. Yokoyama, M. Nakatake, T. Kuwata, A. Couzinet, R. Goitsuka, S. Tsutsumi, H. Aburatani, P. J. Valk, R. Delwel and T. Nakamura.
- MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.
Journal of clinical investigation, 126, 1664-78 (2016)
2015年
- Tanaka, M., Yamaguchi, S., Yamazaki, Y., Kinoshita, H., Kuwahara, K., Nakao, K., Jay, P.Y., Noda, T., Nakamura, T.
- Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model.
Sci Rep, 5, 7826 (2015) - Yoshioka, K., Oda, A., Notsu, C., Ohtsuka, T., Kawai, Y., Suzuki, S., Nakamura, T., Mabuchi, Y., Matsuzaki, Y., Goitsuka, R.
- Loss of the homeodomain transcription factor prep1 perturbs adult hematopoiesis in the bone marrow.
PLoS One, 10, e0136107 (2015)
2014年
- Ariki, R., Morikawa, S., Mabuchi, Y., Suzuki, S., Nakatake, M., Yoshioka, K., Hidano, S., Nakauchi, H., Matsuzaki, Y., Nakamura, T., Goitsuka, R.
- Homeodomain transcription factor meis1 is a critical regulator of adult bone marrow hematopoiesis.
PLoS One, 9, e87646 (2014) - Hirayama, T., Asano, Y., Iida, H., Watanabe, T., Nakamura, T., Goitsuka, R.
- Meis1 is required for the maintenance of postnatal thymic epithelial cells.
PLoS One, 9, e89885 (2014) - Tanaka, M., Yamazaki, Y., Kanno, Y., Igarashi, K., Aisaki, K.I., Kanno, J., Nakamura, T.
- Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors.
J Clin Invest, (2014) - Okumura, K., Saito, M., Isogai, E., Aoto, Y., Hachiya, T., Sakakibara, Y., Katsuragi, Y., Hirose, S., Kominami, R., Goitsuka, R., Nakamura, T., Wakabayashi, Y.
- Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
PLoS One, 9, e102111 (2014) - Tanaka, M., Aisaki, K.I., Kitajima, S., Igarashi, K., Kanno, J., Nakamura, T.
- Gene expression response to EWS-FLI1 in mouse embryonic cartilage.
Genom Data, 2, 296-298 (2014)
2012年
- Yokoyama, T., Toki, T., Aoki, Y., Kanezaki, R., Park, M., Kanno, Y., Takahara, T., Yamazaki, Y., Ito, E., Hayashi, Y., Nakamura, T.
- Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia.
Blood, in press (2012)
2011年
- Funasaka, T., Nakano, H., Wu, Y., Hashizume, C., Gu, L., Nakamura, T., Wang, W., Zhou, P., Moore, M.A.S., Sato, H., Wong, R.W.
- RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis.
Cell Cycle, 10, 1456-1467 (2011) - Kurata, M., Yamazaki, Y., Kanno, Y., Ishibashi, S., Takahara, T., Kitagawa, M., Nakamura, T.
- Anti-apoptotic function of Xbp1 as an IL-3 signaling molecule in hematopoietic cells.
Cell Death Dis, 2, e118 (2011) - Okada, Y., Kamata, S., Akashi, T., Kurata, M., Nakamura, T., Kihara, K.
- Primitive neuroectodermal tumor/Ewing's sarcoma of the urinary bladder: a case report and its molecular diagnosis.
Int J Clin Oncol, 16, 435-438 (2011) - Tsuruyama, T., Hiratsuka, T., Jin, G., Imai, Y., Takeuchi, H., Maruyama, Y., Kanaya, K., Ozeki, M., Takakuwa, T., Haga, H., Tamaki, K., Nakamura, T.
- Murine leukemia retrovirus integration induces the formation of transcription factor complexes on palindromic sequences in the signal transducer and activator of transcription factor 5a gene during the development of pre-B lymphomagenesis.
Am J Pathol, 178, 1374-1386 (2011) - Yokoyama, T., Nakamura, T.
- Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation.
Cancer Sci, 102, 1115-1122 (2011)
2010年
- Fujino, T., Nomura, K., Ishikawa, Y., Makino, H., Umezawa, A., Aburatani, H., Nagasaki, K., Nakamura, T.
- Function of EWS-POU5F1 in sarcomagenesis and tumor cell maintenance.
Am J Pathol, 176, 1973-1982 (2010) - Kaszynski, R.H., Akatsuka, S., Hiratsuka, T., Jin, G., Ozeki, M., Okuno, T., Nakamura, T., Manabe, T., Takakuwa, T., Hiai, H., Toyokuni, S., Tamaki, K., Tsuruyama, T.
- A quantitative trait locus responsible for inducing B-cell lymphoblastic lymphoma is a hotspot for microsatellite instability.
Cancer Sci, 101, 800-805 (2010) - Taketani, T., Taki, T., Nakamura, T., Kobayashi, Y., Ito, E., Fukuda, S., Yamaguchi, S., Hayashi, Y.
- High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes.
Leukemia, 24, 1975-1977 (2010) - Tsuruyama, T., Imai, Y., Takeuchi, H., Hiratsuka, T., Maruyama, Y., Kanaya, K., Kaszynski, R., Jin, G., Okuno, T., Ozeki, M., Nakamura, T., Takakuwa, T., Manabe, T., Tamaki, K., Hiai, H.
- Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas.
J Leukoc Biol, 88, 107-116 (2010) - Tsuruyama, T., Nakai, T., Hiratsuka, T., Jin, G., Nakamura, T., Yoshikawa, K.
- In vitro HIV-1 selective integration into the target sequence and decoy-effect of the modified sequence.
PLos ONE, 5, e13841 (2010) - Yokoyama, T., Kanno, Y., Yamazaki, Y., Takahara, T., Miyata, S., Nakamura, T.
- Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis.
Blood, 116, 2768-2775 (2010)
2009年
- Komai, Y., Fujiwara, M., Fujii, Y., Mukai, H., Yonese, J., Kawakami, S., Yamamoto, S., Migita, T., Ishikawa, Y., Kurata, M., Nakamura, T., Fukui, I.
- Adult Xp11 translocation renal cell carcinoma diagnosed by cytogenetics and immunohistochemistry.
Clin Cancer Res, 15, 1170-1176 (2009) - Makino, H., Toyoda, M., Matsumoto, K., Saito, H., Nishino, K., Fukawatase, Y., Machida, M., Akutsu, H., Uyama, T., Miyagawa, Y., Okita, H., Kiyokawa, N., Fujino, T., Ishikawa, Y., Nakamura, T., Umezawa, A.
- Mesenchymal to embryonic incomplete transition of human cells by chimeric OCT4/3 (POU5F1) with physiological co-activator EWS.
Exp Cell Res, 315, 2727-2740 (2009) - Miyazaki, K., Yamasaki, N., Oda, H., Kuwata, T., Kanno, Y., Miyazaki, M., Komeno, Y., Kitaura, J., Honda, Z., Warming, S., Jenkins, N.A., Copeland, N.G., Kitamura, T., Nakamura, T., Honda, H.
- Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia.
Blood, 113, 4702-4710 (2009)
2008年
- Hiratsuka, T., Tsuruyama, T., Kaszynski, R., Kometani, K., Minato, N., Nakamura, T., Tamaki, K., Hiai, H.
- Bone marrow pre-B expansion by SL/Kh-Bomb1 locus: not sufficient for lymphomagenesis.
Leuk Res, 32, 309-314 (2008) - Kuwata, T., Nakamura, T.
- BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body.
Genes Cells, 13, 931-940 (2008) - Su, Q., Prosser, H.M., Campos, L.S., Ortiz, M., Nakamura, T., Warren, M., Dupuy, A.J., Jenkins, N.A., Copeland, N.G., Bradley, A., Liu, P.
- A DNA transposon-based approach to validate oncogenic mutations in the mouse.
Proc Natl Acad Sci U S A, 105, 19904-19909 (2008) - Tanaka, M., Jin, G., Yamazaki, Y., Takahara, T., Takuwa, M., Nakamura, T.
- Identification of candidate cooperative genes of the Apc mutation in transformation of the colon epithelial cell by retroviral insertional mutagenesis.
Cancer Sci, 99, 979-985 (2008)
2007年
- Jin, G., Yamazaki, Y., Takuwa, M., Takahara, T., Kaneko, K., Kuwata, T., Miyata, S., Nakamura, T.
- Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.
Blood, 109, 3998-4005 (2007)
2006年
- Kawamura-Saito, M., Yamazaki, Y., Kaneko, K., Kawaguchi, N., Kanda, H., Mukai, H., Gotoh, T., Motoi, T., Fukayama, M., Aburatani, H., Takizawa, T., Nakamura, T.
- Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation.
Hum Mol Genet, 15, 2125-2137 (2006)
2005年
- Iwasaki, M., Kuwata, T., Yamazaki, Y., Jenkins, N.A., Copeland, N.G., Osato, M., Ito, Y., Kroon, E., Sauvageau, G., Nakamura, T.
- Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood, 105, 784-793 (2005)
- Yamaguchi, S., Yamazaki, Y., Ishikawa, Y., Kawaguchi, N., Mukai, H., Nakamura, T.
- EWSR1 is fused to POU5F1 in a bone tumor with translocation t(6;22)(p21;q12). Genes Chromosomes Cancer, 43, 217-222 (2005)
- Yanagida, M., Osato, M., Yamashita, N., Liqun, H., Jacob, B., Wu, F., Cao, X., Nakamura, T., Yokomizo, T., Takahashi, S., Yamamoto, M., Shigesada, K., Ito, Y.
- Increased dose of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice. Oncogene, 24, 4477-4485 (2005)
- Yamashita, N., Osato, M., Huang, L., Yanagida, M., Kogan, S.C., Iwasaki, M., Nakamura, T., Shigesada, K., Asou, N., Ito, Y.
- Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice. Br J Haematol, 131, 495-507 (2005)