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病理部

最終更新日 : 2021年5月27日

部の紹介


病理部長 竹内 賢吾

病理部は、 病院のための診断活動を高いレベルで遂行すると共に、 主として診断と予防に関する研究活動を行っています。特に近年は、 がんの個別化医療実現のための"癌研ゲノムプロジェクト"に積極的に参加し、 化学療法や放射線療法のより正確な組織学的効果判定基準の確立と、 各臓器がんの組織学的治療感受性診断学の前進に努めています。また、 外科的・内視鏡的切除材料の断端診断学を高度化し、 最も合理的な術後治療方針の決定に貢献してきています。さらに、 各臓器の前がん病変や早期がんの形質と遺伝子変化の解析および長期追跡を通じ、 病変の性格、 特に悪性転化ポテンシャルを明らかにしようとしています。

未来の展望

癌研では、研究所に病理部があり、病院の病理部を兼ねています。それゆえ、伝統的に病院と研究所、あるいは研究型の各部門を結ぶ要として機能してきました。今後も高度な病理診断を提供するのみでなく、癌研の特質でもある協調性や総合性をいっそう促進する存在となるよう努める決意です。病院で切除された手術材料を系統的に収集・保管して研究に役立てるGanken Tissue Bankも病理部を中心に運営されますし、遺伝子変換マウスにおける病理解析にも、ヒトの病気の形態学に関する知識の蓄積のある病理が積極的に参加するのが良いと考えています。形態学診断は、今後、遺伝子発現解析により治療感受性指標が確立されていく過程で重要なだけでなく、その結果を取り込むことで、自らも飛躍させることができると考えられるので、その方向の研究も加速させたいと考えています。

研究内容

  1. 治療効果判定法などに関する消化管グループの研究
  2. 胆膵グループによる前癌病変・上皮内がんの研究
  3. 治療選択への寄与を目指す頭頚部グループの研究
  4. 乳癌グループの研究
  5. 実験肝癌モデルを用いた肝がんの発がんメカニズムの研究
  6. 婦人科がんの病理学的研究
  7. 肺がんの診断,原因を追求する臨床病理学的,分子生物学的研究
  8. 泌尿器科腫瘍の臨床病理学的研究 - 染色体解析も援用して
  9. 骨軟部腫瘍の病理学的研究
  10. 血液腫瘍の病理学的,分子生物学的研究
  11. ヒト発癌に関する病理学的研究 - 環境因子・遺伝性因子に注目して

代表論文

研究業績へ

2021年

Horii, R., Nitta, H., Nojima, M., Maruyama, R., Ueno, T., Ito, Y., Ohno, S., Banks, P., Kanda, H. and Akiyama, F. (2021)
Predictive significance of HER2 intratumoral heterogeneity, determined by simultaneous gene and protein analysis, for resistance to trastuzumab-based treatments for HER2-positive breast cancer. Virchows Arch.: in press
Inamura, K. (2021)
Adjuvant chemotherapy in patients with early-stage non-small cell lung cancer. JAMA Oncol: in press
Maeshima, Y., Osako, T., Morizono, H., Yunokawa, M., Miyagi, Y., Kikuchi, M., Ueno, T., Ohno, S. and Akiyama, F. (2021)
Metastatic ovarian cancer spreading into mammary ducts mimicking an in situ component of primary breast cancer: a case report. J. Med. Case Rep., 15: 78
Tsugeno, Y., Kawachi, H., Kirimura, S., Hirota, Y., Shintaku, H., Ito, T., Kikuchi, A., Ohtsuka, K., Akashi, T. and Kitagawa, M. (2021)
Adenocarcinoma arising in the multiple heterotopic submucosal glands of the intestine in a Satoyoshi syndrome patient: A case report. Pathol. Int., 71: 147-154
Amori G, Sugawara E, Shigematsu Y, Akiya M, Kunieda J, Yuasa T, Yamamoto S, Yonese J, Takeuchi K, Inamura K.
Tumor B7-H3 expression in diagnostic biopsy specimens and survival in patients with metastatic prostate cancer. Prostate Cancer Prostatic Dis. 2021 Feb 8. doi: 10.1038/s41391-021-00331-6. Online ahead of print. PMID: 33558663

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2020年

Ebina, A., Togashi, Y., Baba, S., Sato, Y., Sakata, S., Ishikawa, M., Mitani, H., Takeuchi, K. and Sugitani, I. (2020)
TERT promoter mutation and extent of thyroidectomy in patients with 1-4 cm intrathyroidal papillary carcinoma. Cancers (Basel), 12: 2115
Horii, R., Tsuda, H., Masuda, S., Sugita, H., Togashi, K., Ohno, S. and Akiyama, F. (2020)
Performance analysis of the anti-Ki67 antibody clone 30-9 for immunohistochemical staining of breast cancer. Breast Cancer, 27: 1058-1064
Inamura, K. (2020)
Ethical Considerations about Genomic Medicine Implementation: Lessons Learned from the eMERGE III Study. Journal of personalized medicine, 10: E195
Inamura, K. (2020)
Gut microbiota contributes towards immunomodulation against cancer: New frontiers in precision cancer therapeutics. Semin. Cancer Biol.: in press
Inamura, K. (2020)
Roles of microbiota in response to cancer immunotherapy. Semin. Cancer Biol., 65: 164-175
Ishii, S., Ito, T., Yamada, M., Yamazaki, N., Ikebata, K., Fujiyama, J., Furuta, N., Komatsu, K., Takeuchi, K., Sugiyama, Y. and Takazawa, Y. (2020)
Characteristic cytological findings of lobular endocervical glandular hyperplasia associated with adenocarcinoma of the uterine cervix. Acta Cytol., 64: 556-562
Luangxay, T., Osako, T., Yonekura, R., Sugiura, Y., Kikuchi, M., Gomi, N., Ueno, T., Ohno, S., Machinami, R., Takeuchi, K. and Akiyama, F. (2020)
Giant cell tumor of soft tissue of the breast: Case report with H3F3A mutation analysis and review of the literature. Pathol. Res. Pract., 216: 152750
Naito, K., Shigematsu, Y., Fujiwara, Y., Inamura, K., Togashi, Y., Inoue, Y., Takazawa, Y., Kanda, H. and Matsueda, K. (2020)
Identification of a specific ultrasonographic finding for differentiating hepatic angiomyolipoma from hepatocellular carcinoma. Clin. Imag., 59: 104-108
Nakashima, Y., Inamura, K., Ninomiya, H., Okumura, S., Mun, M., Kirimura, S., Kobayashi, M., Okubo, K. and Ishikawa, Y. (2020)
Frequent expression of conventional endothelial markers in pleural mesothelioma: Usefulness of claudin-5 as well as combined traditional markers to distinguish mesothelioma from angiosarcoma. Lung Cancer, 148: 20-27
Omi, M., Tonooka, A., Chiba, T., Tanaka, Y., Fusegi, A., Aoki, Y., Nomura, H., Kanao, H. and Takazawa, Y. (2020)
Immunohistochemical markers and the clinical course of adenosarcoma: a series of seven cases. Diagn. Pathol., 15: 119
Osako, T., Lee, H., Turashvili, G., Chiu, D. Y., McKinney, S., Joosten, S. E. P., Wilkinson, D. S., Nielsen, T. O., Zwart, W., Emerman, J. T., Eaves, C. J., Caldas, C. and Aparicio, S. (2020)
Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects. Nature Cancer, 1: 518-532
Sakamoto, K. and Takeuchi, K. (2020)
Cytogenetics of blastic plasmacytoid dendritic cell neoplasm: Chromosomal rearrangements and DNA copy-number alterations. Hematol. Oncol .Clin .North Am., 34: 523-538
Shigematsu, Y., Yamashita, K., Takamatsu, M., Tanizawa, T., Togashi, Y., Nakajima, T., Chino, A., Kawachi, H. and Takeuchi, K. (2020)
Primary intramucosal synovial sarcoma of the sigmoid colon in a patient with a germline mutation in the MSH2 gene: A case report. Pathol. Int., 70: 1015-1019
Tsugeno, Y., Nakano, K., Nakajima, T., Namikawa, K., Takamatsu, M., Yamamoto, N., Fujisaki, J., Nunobe, S., Kitagawa, M., Takeuchi, K. and Kawachi, H. (2020)
Histopathologic analysis of signet-ring cell carcinoma in situ in patients with hereditary diffuse gastric cancer. Am. J. Surg. Pathol., 44: 1204-1212
Wakejima, R., Inamura, K., Ninomiya, H., Nagano, H., Mun, M., Okumura, S., Okubo, K. and Ishikawa, Y. (2020)
Mucinous lung adenocarcinoma, particularly referring to EGFR-mutated mucinous adenocarcinoma. Pathol. Int., 70: 72-83
Yamamoto, T., Gulanbar, A., Hayashi, K., Kohno, A., Komai, Y., Yonese, J., Matsueda, K. and Inamura, K. (2020)
Is hypervascular papillary renal cell carcinoma present? Abdom. Radiol.: in press
Yoshimizu, S., Kawachi, H., Yamamoto, Y., Nakano, K., Horiuchi, Y., Ishiyama, A., Tsuchida, T., Yoshio, T., Hirasawa, T., Ito, H. and Fujisaki, J. (2020)
Clinicopathological features and risk factors for lymph node metastasis in early-stage non-ampullary duodenal adenocarcinoma. J. Gastroenterol., 55: 754-762

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2019年

Chang, K. C., Yu-Yun Lee, J., Sakamoto, K., Baba, S. and Takeuchi, K. (2019)
Blastic plasmacytoid dendritic cell neoplasm with immunoblastoid morphology and MYC rearrangement and overexpression. Pathology, 51: 100-102
Hashimoto, H., Tsugeno, Y., Sugita, K. and Inamura, K. (2019)
Mesenchymal tumors of the lung: diagnostic pathology, molecular pathogenesis, and identified biomarkers. J. Thorac. Dis., 11: S9-S24
Hashimoto, H., Usui, G., Tsugeno, Y., Sugita, K., Amori, G., Morikawa, T. and Inamura, K. (2019)
Cerebral thromboembolism after lobectomy for lung cancer: Pathological diagnosis and mechanism of thrombus formation. Cancers (Basel), 11: E-488
Inamura, K., Amori, G., Yuasa, T., Yamamoto, S., Yonese, J. and Ishikawa, Y. (2019)
Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma. Cancer Manag. Res., 11: 7021-7030
Ishioka, M., Hirasawa, T., Kawachi, H., Nakano, K., Kunieda, J., Yoshimizu, S., Horiuchi, Y., Ishiyama, A., Yoshio, T., Tsuchida, T. and Fujisaki, J. (2019)
Enterochromaffin-like cell neuroendocrine tumor associated with parietal cell dysfunction. Gastrointest. Endosc., 90: 841-845.e841
Kawachi, H. (2019)
Histopathological diagnosis of ulcerative colitis-associated neoplasia. Dig. Endosc., 31 Suppl 1: 31-35
Kobayashi, M., Kawachi, H., Pasternak, S., Delgado, C., Pinto, P., Ito, T., Karelovic, S., Carrasco, H., Tanaka, K., Okada, T., Odagaki, T., Zarate, A. J., Ponce, A., Kronberg, U., Lopez-Kostner, F., Tsubaki, M., Kawano, T. and Eishi, Y. (2019)
Histopathologic study from a colorectal cancer screening in Chile: results from the first 2 years of an international collaboration between Chile and Japan. Eur. J. Cancer Prev., 28: 245-253
Matsue, K., Abe, Y., Narita, K., Kobayashi, H., Kitadate, A., Takeuchi, M., Miura, D. and Takeuchi, K. (2019)
Diagnosis of intravascular large B-cell lymphoma: novel insights into clinicopathological features from 42 patients at a single institution over 20 years. Br. J. Haematol., 187: 328-336
Osumi, H., Kawachi, H., Murai, K., Kusafuka, K., Inoue, S., Kitamura, M., Yoshio, T., Kakusima, N., Ishihara, R., Ono, H., Yamamoto, N., Sugino, T., Nakatsuka, S., Ida, S., Nunobe, S., Bando, E., Omori, T., Takeuchi, K. and Fujisaki, J. (2019)
Risk stratification for lymph node metastasis using Epstein-Barr virus status in submucosal invasive (pT1) gastric cancer without lymphovascular invasion: a multicenter observational study. Gastric Cancer, 22: 1176-1182
Osumi, H., Kawachi, H., Yoshio, T., Ida, S., Yamamoto, N., Horiuchi, Y., Ishiyama, A., Hirasawa, T., Tsuchida, T., Hiki, N., Takeuchi, K. and Fujisaki, J. (2019)
Epstein-Barr virus status is a promising biomarker for endoscopic resection in early gastric cancer: proposal of a novel therapeutic strategy. J. Gastroenterol., 54: 774-783
Takamatsu, M., Kawachi, H., Yamamoto, N., Kobayashi, M., Toyama, Y., Maekawa, T., Chino, A., Saito, S., Ueno, M., Takazawa, Y. and Ishikawa, Y. (2019) Immunohistochemical evaluation of tumor budding for stratifying
T1 colorectal cancer: optimal cut-off value and a novel computer-assisted semiautomatic method. Mod. Pathol., 32: 675-683
Takamatsu, M., Yamamoto, N., Kawachi, H., Chino, A., Saito, S., Ueno, M., Ishikawa, Y., Takazawa, Y. and Takeuchi, K. (2019)
Prediction of early colorectal cancer metastasis by machine learning using digital slide images. Comput. Methods Programs Biomed., 178: 155-161
Takeuchi, K. (2019)
Discovery stories of RET fusions in lung cancer: A mini-review. Front. Physiol., 10: 216
Tsuyama, N., Yokoyama, M., Fujisaki, J., Oguchi, M., Terui, Y. and Takeuchi, K. (2019)
Villous colonization (glove balloon sign): A histopathological diagnostic marker for follicular lymphomas with duodenal involvement including duodenal-type follicular lymphoma. Pathol. Int., 69: 48-50
Yamamoto, T., Koizumi, M., Kohno, A., Numao, N. and Inamura, K. (2019)
A case report on 111In chloride bone marrow scintigraphy in management of adrenal myelolipoma. Medicine (Baltimore), 98: e14625
Yonekura, R., Horii, R., Iwase, T., Gomi, N., Kitagawa, M., Akiyama, F. and Ohno, S. (2019)
A diagnostic strategy for breast calcifications based on a long-term follow-up of 615 lesions. Jpn. J. Radiol., 37: 237-244
Yonekura R, Osako T, Iwase T, Ogiya A, Ueno T, Kitagawa M, et al.
Prognostic impact and possible pathogenesis of lymph node metastasis in ductal carcinoma in situ of the breast. Breast Cancer Res Treat. 2019;174(1):103-11.

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2018年

Dobashi, A., Togashi, Y., Tanaka, N., Yokoyama, M., Tsuyama, N., Baba, S., Mori, S., Hatake, K., Yamaguchi, T., Noda, T. and Takeuchi, K. (2018)
TP53 and OSBPL10 alterations in diffuse large B-cell lymphoma: prognostic markers identified via exome analysis of cases with extreme prognosis. Oncotarget, 9: 19555-19568
Inamura, K. (2018)
Bladder cancer: New insights into its molecular pathology. Cancers (Basel), 10: pii: E100
Inamura, K. (2018)
Clinicopathological characteristics and mutations driving development of early lung Adenocarcinoma: tumor initiation and progression. Int. J. Mol. Sci., 19: pii: E1259
Inamura, K. (2018)
Prostatic cancers: understanding their molecular pathology and the 2016 WHO classification. Oncotarget, 9: 14723-14737
Inamura, K. (2018)
Update on immunohistochemistry for thedDiagnosis of lung cancer. Cancers (Basel), 10: pii: E72
Inamura, K., Shigematsu, Y., Ninomiya, H., Nakashima, Y., Kobayashi, M., Saito, H., Takahashi, K., Futaya, E., Okumura, S., Ishikawa, Y. and Kanda, H. (2018)
CSF1R-expressing tumor-associated macrophages, smoking and survival in lung adenocarcinoma: Analyses using quantitative phosphor-integrated dot staining. Cancers (Basel), 10: E252
Inamura, K., Takazawa, Y., Inoue, Y., Yokouchi, Y., Kobayashi, M., Saiura, A., Shibutani, T. and Ishikawa, Y. (2018)
Tumor B7-H3 (CD276) expression and survival in pancreatic cancer. J. Clin. Med., 7: 172
Inoue, H., Horii, R., Ito, Y., Iwase, T., Ohno, S. and Akiyama, F. (2018)
Tumor-infiltrating lymphocytes affect the efficacy of trastuzumab-based treatment in human epidermal growth factor receptor 2-positive breast cancer. Breast Cancer, 25: 268-274
Kanda, H., Furuta, N., Takazawa, Y., Furuta, R., Ae, K., Sugiyama, Y. and Ishikawa, Y. (2018)
Cytological findings of gastrointestinal stromal tumor-derived bone metastasis. Acta Cytol., 62: 430-435
Noma, D., Inamura, K., Matsuura, Y., Hirata, Y., Nakajima, T., Yamazaki, H., Hirai, Y., Ichinose, J., Nakao, M., Ninomiya, H., Mun, M., Nakagawa, K., Masuda, M., Ishikawa, Y. and Okumura, S. (2018)
Prognostic effect of lymphovascular invasion on TNM staging in stage I non-small-cell lung cancer. Clin. Lung Cancer, 19: e109-e122
Sakamoto, K., Katayama, R., Asaka, R., Sakata, S., Baba, S., Nakasone, H., Koike, S., Tsuyama, N., Dobashi, A., Sasaki, M., Ichinohasama, R., Takakuwa, E., Yamazaki, R., Takizawa, J., Maeda, T., Narita, M., Izutsu, K., Kanda, Y., Ohshima, K. and Takeuchi, K. (2018)
Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm: association with immunoblastoid cytomorphology, MYC expression, and drug response. Leukemia, 32: 2590-2603
Shigematsu, Y. and Inamura, K. (2018)
Gut microbiome: a key player in cancer immunotherapy. Hepatobiliary Surg. Nutr., 7: 479-480
Shigematsu, Y., Inamura, K., Mise, Y., Saiura, A., Rehnberg, E., Yamamoto, N., Ishikawa, Y., Takahashi, S. and Kanda, H. (2018)
CDX2 expression is concordant between primary colorectal cancer lesions and corresponding liver metastases independent of chemotherapy: a single-center retrospective study in Japan. Oncotarget, 9: 17056-17065
Shigematsu, Y., Inamura, K., Yamamoto, N., Mise, Y., Saiura, A., Ishikawa, Y., Takahashi, S. and Kanda, H. (2018)
Impact of CDX2 expression status on the survival of patients after curative resection for colorectal cancer liver metastasis. BMC Cancer, 18: 980
Shigematsu, Y., Kanda, H., Nagasaki, T., Inoue, Y. and Takahashi, S. (2018)
Hepatic eosinophilic abscesses associated with sigmoid colon cancer Intern. Med., 57: 1405-1409
Subat, S., Inamura, K., Ninomiya, H., Nagano, H., Okumura, S. and Ishikawa, Y. (2018)
Unique MicroRNA and mRNA Interactions in EGFR-Mutated Lung Adenocarcinoma. J. Clin. Med., 7: 419
Takamatsu, M., Sato, Y., Muto, M., Nagano, H., Ninomiya, H., Sakakibara, R., Baba, S., Sakata, S., Takeuchi, K., Okumura, S. and Ishikawa, Y. (2018)
Hyalinizing clear cell carcinoma of the bronchial glands: presentation of three cases and pathological comparisons with salivary gland counterparts and bronchial mucoepidermoid carcinomas. Mod. Pathol., 31: 923-933
Togashi, Y., Dobashi, A., Sakata, S., Sato, Y., Baba, S., Seto, A., Mitani, H., Kawabata, K. and Takeuchi, K. (2018)
MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts. Mod. Pathol., 31: 934-946
Tsuyama, N., Asaka, R., Dobashi, A., Baba, S., Mishima, Y., Ueda, K., Oguchi, M., Tsuji, H., Hatake, K. and Takeuchi, K. (2018)
Epstein-Barr virus-negative extranodal “true” natural killer-cell lymphoma harbouring a KDM6A mutation. Hematol. Oncol., 36: 328-335
Yamazaki, K., Horii, R., Iwase, T., Ueno, T., Ohno, S. and Akiyama, F. (2018)
Ductal carcinoma in situ manageable by active surveillance. Ann. Breast Cancer Res., 3: 1-4

このページのTOPへ

2017年

Inamura, K. (2017)
Diagnostic and therapeutic potential of microRNAs in lung cancer. Cancers (Basel), 9: pii: E49.
Inamura, K. (2017)
Lung cancer: Understanding its molecular pathology and the 2015 WHO classification. Front. Oncol., 7: 193
Inamura, K. (2017)
Major tumor suppressor and oncogenic non-coding RNAs: Clinical relevance in lung cancer. Cells, 6: 12
Inamura, K. (2017)
Renal cell tumors: Understanding their molecular pathological epidemiology and the 2016 WHO classification. Int. J. Mol. Sci., 18: pii: E2195
Inamura, K. (2017)
Translocation renal cell carcinoma: An update on clinicopathological and molecular features. Cancers (Basel), 9: pii: E111
Inamura, K., Kobayashi, M., Nagano, H., Sugiura, Y., Ogawa, M., Masuda, H., Yonese, J. and Ishikawa, Y. (2017)
A novel fusion of HNRNPA1-ALK in inflammatory myofibroblastic tumor of urinary bladder. Hum. Pathol., 69: 96-100
Inamura, K., Yokouchi, Y., Kobayashi, M., Ninomiya, H., Sakakibara, R., Nishio, M., Okumura, S. and Ishikawa, Y. (2017)
Relationship of tumor PD-L1 (CD274) expression with lower mortality in lung high-grade neuroendocrine tumor. Cancer Med., 6: 2347-2356
Inamura, K., Yokouchi, Y., Kobayashi, M., Ninomiya, H., Sakakibara, R., Subat, S., Nagano, H., Nomura, K., Okumura, S., Sibutani, T. and Ishikawa, Y. (2017)
Association of tumor TROP2 expression with prognosis varies among lung cancer subtypes. Oncotarget, 8: 28725-28735
Inamura, K., Yokouchi, Y., Kobayashi, M., Sakakibara, R., Ninomiya, H., Subat, S., Nagano, H., Nomura, K., Okumura, S., Shibutani, T. and Ishikawa, Y. (2017) T
umor B7-H3 (CD276) expression and smoking history in relation to lung adenocarcinoma prognosis. Lung Cancer, 103: 44-51
Muto, M., Inamura, K., Ozawa, N., Endo, T., Masuda, H., Yonese, J. and Ishikawa, Y. (2017)
Skene's gland adenocarcinoma with intestinal differentiation: A case report and literature review. Pathol. Int., 67: 575-579
Osako, T., Iwase, T., Ushijima, M., Yonekura, R., Ohno, S. and Akiyama, F. (2017)
A new molecular-based lymph node staging classification determines the prognosis of breast cancer patients. Br. J. Cancer., 117: 1470-1477
Sakakibara, R., Inamura, K., Tambo, Y., Ninomiya, H., Kitazono, S., Yanagitani, N., Horiike, A., Ohyanagi, F., Matsuura, Y., Nakao, M., Mun, M., Okumura, S., Inase, N., Nishio, M., Motoi, N. and Ishikawa, Y. (2017)
EBUS-TBNA as a promising method for the evaluation of tumor PD-L1 expression in lung cancer. Clin. Lung Cancer, 18: 527-534
Shigematsu, Y., Kanda, H., Konishi, T., Takazawa, Y., Inoue, Y., Muto, T., Ishikawa, Y. and Takahashi, S. (2017)
Recurrence 30 years after surgical resection of localized rectal neuroendocrine tumor. Intern. Med., 56: 1521-1525
Tsuyama, N., Ennishi, D., Yokoyama, M., Baba, S., Asaka, R., Mishima, Y., Terui, Y., Hatake, K. and Takeuchi, K. (2017)
Clinical and prognostic significance of aberrant T-cell marker expression in 225 cases of de novo diffuse large B-cell lymphoma and 276 cases of other B-cell lymphomas. Oncotarget, 8: 33487-33500
Tsuyama, N., Sakamoto, K., Sakata, S., Dobashi, A. and Takeuchi, K. (2017)
Anaplastic large cell lymphoma: pathology, genetics, and clinical aspects. J. Clin. Exp. Hematop., 57: 120-142
Tsuyama, N., Sakata, S., Baba, S., Mishima, Y., Nishimura, N., Ueda, K., Yokoyama, M., Terui, Y., Hatake, K., Kitagawa, M., Ishizuka, N., Tomita, N. and Takeuchi, K. (2017)
BCL2 expression in DLBCL: reappraisal of immunohistochemistry with new criteria for therapeutic biomarker evaluation. Blood, 130: 489-500

このページのTOPへ

2016年

Dobashi, A., Tsuyama, N., Asaka, R., Togashi, Y., Ueda, K., Sakata, S., Baba, S., Sakamoto, K., Hatake, K. and Takeuchi, K. (2016)
Frequent BCOR aberrations in extranodal NK/T-Cell lymphoma, nasal type. Genes Chromosomes Cancer, 55: 460-471
Horii, R. and Akiyama, F. (2016)
Histological assessment of therapeutic response in breast cancer. Breast Cancer, 23: 540-545
Horii, R., Honma, N., Ogiya, A., Kozuka, Y., Yoshida, K., Yoshida, M., Horiguchi, S. I., Ito, Y. and Mukai, H. (2016)
The Japanese Breast Cancer Society clinical practice guidelines for pathological diagnosis of breast cancer, 2015 edition. Breast Cancer, 23: 391-399
Inamura, K. and Ishikawa, Y. (2016)
MicroRNA In lung cancer: Novel biomarkers and potential tools for treatment. J. Clin. Med., 5: pii: E36
Inamura, K., Yokouchi, Y., Sakakibara, R., Kobayashi, M., Subat, S., Ninomiya, H., Nagano, H., Nomura, K., Okumura, S. and Ishikawa, Y. (2016)
Relationship of tumor PD-L1 expression with EGFR wild-type status and poor prognosis in lung adenocarcinoma. Jpn. J. Clin. Oncol., 46: 935-941
Kanda, H., Furuta, R., Motoi, N., Suzuki, N., Furuta, N., Komatsu, K., Sugiyama, Y., Saiura, A., Sugitani, M. and Ishikawa, Y. (2016)
Touch cytology smear of an inflammatory hepatocellular adenoma displaying an unusual pattern: A case report. Diagn. Cytopathol., 44: 1074-1077
Kobayashi, K., Horii, R., Ito, Y., Ohno, S., Iwase, T. and Akiyama, F. (2016)
Prognostic significance of histological therapeutic effect in preoperative chemotherapy for breast cancer. Pathol. Int., 66: 8-14
Nakagawa, T., Horii, R., Ito, Y., Iwase, T. and Akiyama, F. (2016)
Development of an easy method to test for HER2 in breast cancer using dual-color in situ hybridization. Breast Cancer, 23: 78-84
Noma, D., Inamura, K., Mun, M., Terauchi, T., Matsuura, Y., Nakao, M., Ninomiya, H., Nakagawa, K., Masuda, M., Okumura, S. and Ishikawa, Y. (2016)
Thymic oncocytic carcinoid with a markedly elevated level of maximum SUV. Pathol. Int., 66: 593-595
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