| 2021年12月7日 |
Kohda, Y., Sakamoto, S., Umekita, M., Kimura, T., Kubota, Y., Arisaka, R., Shibuya, Y., Muramatsu, H., Sawa, R., Dan, S., Kawada, M. and Igarashi, M. Isolation of new derivatives of the 20-membered macrodiolide bispolide from Kitasatospora sp. MG372-hF19.
J. Antibiot. (Tokyo), in press (2021) |
| 2021年12月7日 |
Yoshida, J., Ohishi, T., Abe, H., Ohba, S., Inoue, H., Usami, I., Amemiya, M., Oriez, R., Sakashita, C., Dan, S., Sugawara, M., Kawaguchi, T., Ueno, J., Asano, Y., Ikeda, A., Takamatsu, M., Amori, G., Kondoh, Y., Honda, K., Osada, H., Noda, T., Watanabe, T., Shimmizu, T., Shibasaki, M. and Kawada, M. Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment.
iScience, in press (2021) |
| 2021年12月1日 |
Okamoto, N., Ohto, T., Enokizono, T., Wada, Y., Kohmoto, T., Imoto, I., Haga, Y., Seino, J. and Suzuki, T. Siblings with MAN1B1-CDG Showing Novel Biochemical Profiles.
Cells, 10, (2021) |
| 2021年11月4日 |
Kurata, M., Onishi, I., Takahara, T., Yamazaki, Y., Ishibashi, S., Goitsuka, R., Kitamura, D., Takita, J., Hayashi, Y., Largaesapda, D. A., Kitagawa, M. and Nakamura, T. C/EBPβ induces B-cell acute lymphoblastic leukemia and cooperates with BLNK mutations.
Cancer Sci., in press (2021) |
| 2021年11月4日 |
Sunami, Y., Yokoyama, T., Yoshino, S., Takahara, T., Yamazaki, Y., Harada, H. and Nakamura, T. BCL11A promotes myeloid leukemogenesis by repressing PU.1 target genes.
Blood Adv., in press (2021) |
| 2021年10月25日 |
Okumura, S., Konishi, Y., Narukawa, M., Sugiura, Y., Yoshimoto, S., Arai, Y., Sato, S., Yoshida, Y., Tsuji, S., Uemura, K., Wakita, M., Matsudaira, T., Matsumoto, T., Kawamoto, S., Takahashi, A., Itatani, Y., Miki, H., Takamatsu, M., Obama, K., Takeuchi, K., Suematsu, M., Ohtani, N., Fukunaga, Y., Ueno, M., Sakai, Y., Nagayama, S. and Hara, E. Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion.
Nat. Commun., 12, 5674 (2021) |
| 2021年9月10日 |
Osako, T., Kurisaki-Arakawa, A., Dobashi, A., Togashi, Y., Baba, S., Shiozawa, S., Ishigame, H., Ishige, H., Ohno, S., Ishikawa, Y. and Takeuchi, K. Distinct clinicopathologic features and possible pathogenesis of localized ALK-positive histiocytosis of the breast.
Am. J. Surg. Pathol., in press (2021) |
| 2021年8月30日 |
Isoyama, S., Mori, S., Sugiyama, D., Kojima, Y., Tada, Y., Shitara, K., Hinohara, K., Dan, S. and Nishikawa, H.
Cancer immunotherapy with PI3K and PD-1 dual-blockade via optimal modulation of T cell activation signal.
J. Immunother. Cancer, 9, (2021)
|
| 2021年8月24日 |
Miyata, K., Imai, Y., Hori, S., Nishio, M., Loo, T. M., Okada, R., Yang, L., Nakadai, T., Maruyama, R., Fujii, r., Ueda, K., Jiang, L., Zheng, H., Toyokuni, S., Sakata, T., Shirahige, K., Kojima, R., Nakayama, M., Oshima, M., Nagayama, S., Hara, E. and Takahashi, A. Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.
Proc. Natl. Acad. Sci. U. S. A., 118, e2025647118 (2021)
|
| 2021年8月16日 |
Iwao, Y., Okamoto, Y., Shirahama, H., Tsukahara, S. and Tomida, A. eIF4B enhances ATF4 expression and contributes to cellular adaptation to asparagine limitation in BRAF-mutated A375 melanoma.
Biochem. Biophys. Res. Commun., 573, 93-99 (2021) |
| 2021年8月16日 |
Tanaka, M. and Nakamura, T. Modeling fusion gene-associated sarcoma: Advantages for understanding sarcoma biology and pathology.
Pathol. Int., in press (2021) |
| 2021年8月16日 |
Yoshino, S., Tanaka, M., Sunami, Y., Takahara, T., Yamazaki, Y., Homme, M., Niibori-Nambu, A., Osato, M., Minami, T., Ishihara, K. and Nakamura, T. Trib1 promotes the development of acute myeloid leukemia in a Ts1Cje mouse model of Down syndrome.
Leukemia, in press |
| 2021年8月3日 |
Otsuji, K., Sasaki, T., Tanabe, M. and Seto, Y.
Quantitative assessment of HER2 gene amplification of breast cancer using droplet digital PCR.
Pathol. Int., in press (2021)
|
| 2021年7月26日 |
Mashima, T., Wakatsuki, T., Kawata, N., Jang, M. K., Nagamori, A., Yoshida, H., Nakamura, K., Migita, T., Seimiya, H. and Yamaguchi, K.
Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo.
Sci. Rep., in press (2021)
|
| 2021年7月26日 |
Takagi, S., Sasaki, Y., Koike, S., Takemoto, A., Seto, Y., Haraguchi, M., Ukaji, T., Kawaguchi, T., Sugawara, M., Saito, M., Funauchi, Y., Ae, K., Matsumoto, S., Fujita, N. and Katayama, R. Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis.
Oncogene, in press (2021)
|
| 2021年7月26日 |
Seimiya, H., Nagasawa, K. and Shin-Ya, K. Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics.
J. Antibiot., in press (2021)
|
| 2021年7月15日 |
Niinuma, T., Kitajima, H., Yamamoto, E., Maruyama, R., Aoki, H., Harada, T., Ishiguro, K., Sudo, G., Toyota, M., Yoshido, A., Kai, M., Nakase, H., Sugai, T. and Suzuki, H. An integrated epigenome and transcriptome analysis to clarify the effect of epigenetic inhibitors on GIST.
Anticancer Res., 41, 2817-2828 (2021) |
| 2021年7月15日 |
Jo, M., Kusano, Y. and Hirota, T. Unraveling pathologies underlying chromosomal instability in cancers.
Cancer Sci., in press (2021) |
| 2021年7月15日 |
Matsui, S. and Nozawa, R. S. RNA impacts formation of biomolecular condensates in the nucleus.
Biomolecular Research (Tokyo), in press (2021) |
| 2021年7月12日 |
Minegishi, R., Gotoh, O., Tanaka, N., Maruyama, R., Chang, J. T. and Mori, S. A method of sample-wise region-set enrichment analysis for DNA methylomics.
Epigenomics, in press (2021) |
| 2021年6月18日 |
Osako, T. How can we better distinguish metastatic tumors from primary tumors in the breast?
Expert Rev. Anticancer Ther., in press (2021)
|
| 2021年5月20日 |
Akiya, M., Osako, T., Morizono, H., Furuta, N., Kikuchi, M., Ueno, T., Ohno, S. and Takeuchi, K. Myofibroblastoma of the breast showing rare palisaded morphology and uncommon desmin- and CD34-negative immunophenotype: A case report.
Pathol. Int., in press (2021) |
| 2021年4月20日 |
Yoshizawa, T., Uchibori, K., Araki, M., Matsumoto, S., Ma, B., Kanada, R., Seto, Y., Oh-Hara, T., Koike, S., Ariyasu, R., Kitazono, S., Ninomiya, H., Takeuchi, K., Yanagitani, N., Takagi, S., Kishi, K., Fujita, N., Okuno, Y., Nishio, M. and Katayama, R. Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.
NPJ precision oncology, 5, 32 (2021) |
| 2021年4月12日 |
Yamamoto, S., Okamura, K., Fujii, R., Kawano, T., Ueda, K., Yajima, Y. and Shiba, K. Specimen-specific drift of densities defines distinct subclasses of extracellular vesicles from human whole saliva.
PLoS One, 16, e0249526 (2021) |
| 2021年4月7日 |
Tasaki, Y., Suzuki, M., Katsushima, K., Shinjo, K., Iijima, K., Murofushi, Y., Naiki-Ito, A., Hayashi, K., Qiu, C., Takahashi, A., Tanaka, Y., Kawaguchi, T., Sugawara, M., Kataoka, T., Naito, M., Miyata, K., Kataoka, K., Noda, T., Gao, W., Kataoka, H., Takahashi, S., Kimura, K. and Kondo, Y. Cancer-specific targeting of taurine-upregulated gene 1 enhances the effects of chemotherapy in pancreatic cancer.
Cancer Res., in press (2021) |
| 2021年4月6日 |
Uchida, K. S. K., Jo, M., Nagasaka, K., Takahashi, M., Shindo, N., Shibata, K., Tanaka, K., Masumoto, H., Fukagawa, T. and Hirota, T. Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation.
Curr. Biol., in press (2021) |
| 2021年4月6日 |
Watanabe, M., Bhawala, U. K., Takemoto, S., Nishiyama, N., Nakahara, Y., Tatematsu, K. I., Sezuts, H., Kuwabara, N., Minamisawa, T., Shiba, K. and Asakura, T. Bio-functionalized titanium surfaces with modified silk fibroin carrying titanium binding motif to enhance the ossific differentiation of MC3T3-E1.
Biotechnol. Bioeng., in press (2021) |
| 2021年3月19日 |
Ukaji, T., Takemoto, A., Shibata, H., Kakino, M., Takagi, S., Katayama, R. and Fujita, N. Novel knock‐in mouse model for the evaluation of therapeutic efficacy and toxicity of human podoplanin‐targeting agents.
Cancer Sci., in press (2021) |
| 2021年3月12日 |
Ariyasu, R., Uchibori, K., Sasaki, T., Tsukahara, M., Kiyotani, K., Yoshida, R., Ono, Y., Kitazono, S., Ninomiya, H., Ishikawa, Y., Mizukami, Y., Yanagitani, N., Fujita, N., Nishio, M. and Katayama, R. Monitoring EGFR C797S mutation in Japanese NSCLC patients with serial cell free DNA evaluation using digital droplet PCR.
Cancer Sci., in press (2021) |
| 2021年3月12日 |
Okamoto, T., DuVerle, D. A., Yaginuma, K., Natsume, Y., Yamana, H., Fukuda, M., Yamamoto, F., Pe’rraudeau, F., Srivastava, U., Kashima, Y., Suzuki, A., Kuze, Y., Takahashi, Y., Ueno, M., Sakai, Y., Noda, T., Tsuda, K., Suzuki, Y., Nagayama, S. and Yao, R. Comparative analysis of patient-matched PDOs revealed a reduction in OLFM4-associated clusters in metastatic lesions in colorectal cancer.
Stem Cell Rep., in press (2021) |
| 2021年3月2日 |
Yasuda, T., Koiwa, M., Yonemura, A., Miyake, K., Kariya, R., Kubota, S., Yokomizo-Nakano, T., Yasuda-Yoshihara, N., Uchihara, T., Itoyama, R., Bu, L., Fu, L., Arima, K., Izumi, D., Iwagami, S., Eto, K., Iwatsuki, M., Baba, Y., Yoshida, N., Ohguchi, H., Okada, S., Matsusaki, K., Sashida, G., Takahashi, A., Tan, P., Baba, H. and Ishimoto, T.
Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.
Cell Rep., 34, 108779 (2021) |
| 2021年2月25日 |
Mizuta, H., Okada, K., Araki, M., Adachi, J., Takemoto, A., Kutkowska, J., Maruyama, K., Yamagitani, N., Oh-hara, T., Watanabe, K., Tamai, K., Friboulet, l., Katayama, K., Ma, B., Sasakura, Y., Sagae, Y., Kukimoto-Niino, K., Shirouzu, M., Takagi, S., Simizu, S., Nishio, M., Okuno, Y., Fujita, N. and Katayama, R. Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer.
Nat. Commun., 12, 1261 (2021) |
| 2021年2月15日 |
Ikeda, A., Nagayama, S., Sumazaki, M., Konishi, M., Fujii, R., Saichi, N., Muraoka, S., Saigusa, D., Shimada, H., Sakai, Y. and Ueda, K. Colorectal cancer-derived CAT1-positive extracellular vesicles alter nitric oxide metabolism in endothelial cells and promote angiogenesis.
Mol. Cancer Res., in press (2021) |
| 2021年2月12日 |
Hiraga(Kondo), C., Yamamoto, S., Hashimoto, S., Kasahara, M., Minamisawa, T., Matsumura, S., Katakura, A., Yajima, Y., Nomura, T. and Shiba, K. Pentapartite fractionation of particles in oral fluids by differential centrifugation.
Sci. Rep., 11, 3326 (2021) |
| 2021年2月4日 |
Yoshida, R., Hagio, T., Kaneyasu, T., Gotoh, O., Osako, T., Tanaka, N., Amino, S., Yaguchi, N., Nakashima, E., Kitagawa, D., Ueno, T., Ohno, S., Nakajima, T., Nakamura, S., Miki, Y., Hirota, T., Takahashi, S., Matsuura, M., Noda, T. and Mori, S. Pathogenicity assessment of variants for breast cancer susceptibility genes based on BRCAness of tumor sample.
Cancer Sci., in press (2021) |
| 2021年1月28日 |
Obara, R., Kamiya, M., Tanaka, Y., Abe, A., Kojima, R., Kawaguchi, T., Sugawara, M., Takahashi, A., Noda, T. and Urano, Y. γ-Glutamyltranspeptidase (GGT)-Activatable Fluorescence Probe for Durable Tumor Imaging.
Angewandte Chemie (International ed. in English), 60, 2125-2129 (2021) |
| 2021年1月21日 |
Shindo, N., Otsuki, M., Uchida, K. and Hirota, T. Prolonged mitosis causes separase deregulation and chromosome nondisjuction.
Cell Rep., 34, 108652 (2021) |
