| 2024年12月20日 |
Sasaki, N., Homme, M., Murayama, T., Osaki, T., Tenma, T., An, T., Takegami, Y., Tani, T., Gedeon, P. C., Kobayashi, Y., Cañadas, I., Barbie, D. A., Yao, R. and Kitajima, S. RNA sensing induced by chromosome missegregation augments anti-tumor immunity.
Mol. Cell, in press (2024) |
| 2024年11月18日 |
Fujimura, T., Furugaki, K., Mizuta, H., Muraoka, S., Nishio, M., Adachi, J., Uchibori, K., Miyauchi, E., Hayashi, H., Katayama, R. and Yoshiura, S. Targeting ErbB and tankyrase1/2 prevent the emergence of drug-tolerant persister cells in ALK-positive lung cancer.
NPJ Precis. Oncol., 264, in press (2024)
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| 2024年11月15日 |
Okazaki, F., Yorozu, A., Sekiguchi, S., Niinuma, T., Maruyama, R., Kitajima, H., Yamamoto, E., Ishiguro, K., Toyota, M., Hatanaka, Y., Nishiyama, K., Ogi, K., Kai, M., Takano, K., Ichimiya, S., Miyazaki, A. and Suzuki, H. AEBP1 is a negative regulator of skeletal muscle cell differentiation in oral squamous cell carcinoma.
Sci. Rep., 14, 27425 (2024) |
| 2024年11月13日 |
Watanabe, K., Yamamoto, T., Fujita, T., Hino, S., Hino, Y., Yamazaki, K., Ohashi, Y., Sakuraba, S., Kono, H., Nakao, M., Ochiai, K., Dan, S. and Saitoh, N. Metabolically inducing defects in DNA repair sensitizes BRCA–wild-type cancer cells to replication stress.
Science signaling, 17, in press (2024)
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| 2024年10月29日 |
Yamauchi, S., Sugiura, Y., Yamaguchi, J., Zhou, X., Takenaka, S., Odawara, T., Fukaya, S., Fujisawa, T., Naguro, I., Uchiyama, Y., Takahashi, A. and Ichijo, H.
Mitochondrial fatty acid oxidation drives senescence.
Sci. Adv., 10, eado5887 (2024) |
| 2024年10月10日 |
Otsuji, K., Takahashi, Y., Osako, T., Kobayashi, T., Takano, T., Saeki, S., Yang, L., Baba, S., Kumegawa, K., Suzuki, H., Noda, T., Takeuchi, K., Ohno, S., Ueno, T. and Maruyama, R. Serial single-cell RNA sequencing unveils drug resistance and metastatic traits in stage IV breast cancer.
NPJ Precis. Oncol., (2024) |
| 2024年9月13日 |
Wei, X., Uchibori, K., Kondo, N., Utsumi, T., Takemoto, A., Koike, S., Takagi, S., Yanagitani, N., Nishio, M. and Katayama, R. MIG6 loss increased RET inhibitor tolerant persister cells in RET-rearranged non-small cell lung cancer.
Cancer Lett., in press (2024) |
| 2024年9月4日 |
Yanagawa, K., Kuma, A., Hamasaki, M., Kita, S., Yamamuro, T., Nishino, K., Nakamura, S., Omori, H., Kaminishi, T., Oikawa, S., Kato, Y., Edahiro, R., Kawagoe, R., Taniguchi, T., Tanaka, Y., Shima, T., Tabata, K., Iwatani, M., Bekku, N., Hanayama, R., Okada, Y., Akimoto, T., Kosako, H., Takahashi, A., Shimomura, I., Sakata, Y. and Yoshimori, T. The Rubicon-WIPI axis regulates exosome biogenesis during ageing.
Nat. Cell Biol., in press (2024) |
| 2024年8月19日 |
Suenaga, M., Mashima, T., Kawata, N., Dan, S., Seimiya, H. and Yamaguchi, K. Exploratory Study Identifies Matrix Metalloproteinase-14 and -9 as Potential Biomarkers of Regorafenib Efficacy in Metastatic Colorectal Cancer.
Cancers, 16, in press (2024)
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| 2024年7月23日 |
Sasaki, N., Asano, Y., Sorayama, Y., Kamimura, C., Kitano, S., Irie, S., Katayama, R., Shimoda, H. and Matsusaki, M. Promoting Biological Similarity by Collagen Microfibers in 3D Colorectal Cancer-Stromal Tissue: Replicating Mechanical Properties and Cancer Stem Cell Markers.
Acta biomaterialia, in press (2024) |
| 2024年7月16日 |
Yoshida, R., Kaneyasu, T., Ueki, A., Yamauchi, H., Ohsumi, S., Ohno, S., Aoki, D., Baba, S., Kawano, J., Matsumoto, N., Nagasaki, M., Ueno, T., Inari, H., Kobayashi, Y., Takei, J., Gotoh, O., Nishi, M., Okamura, M., Kaneko, K., Okawa, M., Suzuki, M., Amino, S., Inuzuka, M., Noda, T., Mori, S. and Nakamura, S. High-risk pathogenic germline variants in blood relatives of BRCA1/2 negative probands.
Breast Cancer, in press (2024) |
| 2024年7月5日 |
Nagasaka, M., Miyajima, C., Inoue, Y., Hashiguchi, S., Suzuki, Y., Morishita, D., Aoki, H., Toriuchi, K., Katayama, R., Aoyama, M. and Hayashi, H. ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis.
Biochem. Biophys. Res. Commun., 708, in press (2024) |
| 2024年7月5日 |
Otomo, K., Omura, T., Nozawa, Y., Edwards, S. J., Sato, Y., Saito, Y., Yagishita, S., Uchida, H., Watakabe, Y., Naitou, K., Yanai, R., Sahara, N., Takagi, S., Katayama, R., Iwata, Y., Shiokawa, T., Hayakawa, Y., Otsuka, K., Watanabe-Takano, H., Haneda, Y., Fukuhara, S., Fujiwara, M., Nii, T., Meno, C., Takeshita, N., Yashiro, K., Rosales Rocabado, J. M., Kaku, M., Yamada, T., Oishi, Y., Koike, H., Cheng, Y., Sekine, K., Koga, J. I., Sugiyama, K., Kimura, K., Karube, F., Kim, H., Manabe, I., Nemoto, T., Tainaka, K., Hamada, A., Brismar, H. and Susaki, E. A. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques.
Nat. Commun., 15, 4941 (2024) |
| 2024年7月5日 |
Takahashi, Y., Morimura, R., Tsukamoto, K., Gomi, S., Kato, A., Mizukami, M., Naito, Y., Irie, S., Nagayama, S., Shinozaki, E., Yamaguchi, K., Fujita, N., Kitano, S., Katayama, R. and Matsusaki, M. In vitro throughput screening of anticancer drugs using patient-derived cell lines cultured on vascularized three-dimensional stromal tissues.
Acta biomaterialia, in press (2024) |
| 2024年6月25日 |
Yanagiya, R., Miyatake, Y., Watanabe, N., Shimizu, T., Kanamori, A., Ueno, M., Okabe, S., Carreras, J., Nakayama, S., Hasegawa, A., Kameda, K., Kamakura, T., Nakagawa, S., Yamauchi, T., Maeda, T., Ishii, K., Matsuura, T., Handa, H., Hirao, A., Ishizawa, K., Onizuka, M., Mashima, T., Nakamura, N., Ando, K. and Kotani, A. Amino acid influx via LAT1 regulates iron demand and sensitivity to PPMX-T003 of aggressive natural killer cell leukemia.
Leukemia, in press |
| 2024年6月12日 |
Shiraishi, A., Oh-hara, T., Takahashi, Y., Uchibori, K., Nishio, M. and Katayama, R. 3D layered co-culture model enhances Trastuzumab Deruxtecan sensitivity and reveals the combined effect with G007-LK in HER2-positive non-small cell lung cancer.
Biochem. Biophys. Res. Commun., 725, 150255 (2024) |
| 2024年6月5日 |
Shiraishi, R., Cancila, G., Kumegawa, K., Torrejon, J., Basili, I., Bernardi, F., Benites Goncalves da Silva, P., Wang, W., Chapman, O., Yang, L., Jami, M., Nishitani, K., Arai, Y., Xiao, Z., Yu, H., Lo Re, V., Marsaud, V., Talbot, J., Lombard, B., Loew, D., Jingu, M., Okonechnikov, K., Sone, M., Motohashi, N., Aoki, Y., Pfister, S. M., Chavez, L., Hoshino, M., Maruyama, R., Ayrault, O. and Kawauchi, D. Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression.
Dev. Cell, in press (2024) |
| 2024年5月29日 |
Tanaka, H., Sugawara, S., Tanaka, Y., Loo, T. M., Tachibana, R., Abe, A., Kamiya, M., Urano, Y. and Takahashi, A. Dipeptidylpeptidase-4-targeted activatable fluorescent probes visualize senescent cells.
Cancer Sci., in press (2024) |
| 2024年5月24日 |
Sako, K., Furukawa, A., Nozawa, R. S., Kurita, J., Nishimura, Y. and Hirota, T. Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres.
J. Cell. Biol., 229, e202312021 (2024) |
| 2024年5月23日 |
Noda, H., Sakata, S., Baba, S., Togashi, Y., Nakano, K., Hirasawa, T., Nakayama, I., Hata, C., Takamatsu, M., Sugawara, E., Yamamoto, N., Fujisaki, J., Nunobe, S., Iwakiri, K., Takeuchi, K. and Kawachi, H. Early gastric cancer with RhoGAP fusion is linked to frequent nodal metastasis and a part of microtubular-mucocellular histology.
Gastric Cancer, in press (2024) |
| 2024年5月17日 |
Nakamura, A., Mashima, T., Lee, J., Inaba, S., Kawata, N., Morino, S., Kumagai, K., Yamaguchi, K. and Seimiya, H. Intratumor transforming growth factor-β signaling with extracellular matrix-related gene regulation marks chemotherapy-resistant gastric cancer.
Biochemical and Biophysical Research Communications., in press (2024) |
| 2024年5月13日 |
Gotoh, O., Sugiyama, Y., Tonooka, A., Kosugi, M., Kitaura, S., Minegishi, R., Sano, M., Amino, S., Furuya, R., Tanaka, N., Kaneyasu, T., Kumegawa, K., Abe, A., Nomura, H., Takazawa, Y., Kanao, H., Maruyama, R., Noda, T. and Mori, S. Genetic and epigenetic alterations in precursor lesions of endometrial endometrioid carcinoma.
The Journal of pathology, (2024) |
| 2024年4月30日 |
Lee, J., Mashima, T., Kawata, N., Yamamoto, N., Morino, S., Inaba, S., Nakamura, A., Kumagai, K., Wakatsuki, T., Takeuchi, K., Yamaguchi, K. and Seimiya, H. Pharmacological targeting of histone H3K27 acetylation/BRD4-dependent induction of ALDH1A3 for early-phase drug tolerance of gastric cancer.
Cancer Res. Commun., in press (2024) |
| 2024年4月8日 |
Maezawa, M., Watanabe, K. I., Kobayashi, Y., Yoshida, K., Chambers, J. K., Uchida, K., Maruyama, R. and Inokuma, H. Diffuse large B-cell lymphoma with DNA copy number changes in a Japanese black calf.
Veterinary research communications, in press (2024) |
| 2024年3月21日 |
Chuaychob, S., Lyu, R., Tanaka, M., Haginiwa, A., Kitada, A., Nakamura, T. and Yokokawa, R. Mimicking angiogenic microenvironment of alveolar soft-part sarcoma in a microfluidic coculture vasculature chip.
Proc. Natl. Acad. Sci. U. S. A., 121, e2312472121 (2024) |
| 2024年3月7日 |
Okawa, H., Tanaka, Y. and Takahashi, A. Network of extracellular vesicles surrounding senescent cells.
Archives of biochemistry and biophysics, in press (2024)
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| 2024年3月4日 |
Yang, L., Kumegawa, K., Saeki, S., Nakadai, T. and Maruyama, R. Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines.
Cancer gene therapy, in press (2024) |
| 2024年2月26日 |
Suzuki, M., Uchibori, K., Oh-Hara, T., Nomura, Y., Suzuki, R., Takemoto, A., Araki, M., Matsumoto, S., Sagae, Y., Kukimoto-Niino, M., Kawase, Y., Shirouzu, M., Okuno, Y., Nishio, M., Fujita, N. and Katayama, R. A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.
NPJ Precis. Oncol., 8, 46 (2024) |
| 2024年2月19日 |
Shirahama, H., Tani, Y., Tsukahara, S., Okamoto, Y., Hasebe, A., Noda, T., Ando, S., Ushijima, M., Matsuura, M. and Tomida, A. Induction of stearoyl-CoA desaturase confers cell density-dependent ferroptosis resistance in melanoma.
J. Cell. Biochem., in press (2024) |
| 2024年2月15日 |
Kawano, T., Okamura, K., Shinchi, H., Ueda, K., Nomura, T. and Shiba, K. Differentiation of large extracellular vesicles in oral fluid: Combined protocol of small force centrifugation and sedimentation pattern analysis.
Journal of Extracellular Biology, 3, e143 (2024) |
| 2024年1月24日 |
Hirose, S., Mashima, T., Yuan, X., Yamashita, M., Kitano, S., Torii, S., Migita, T. and Seimiya, H. Interleukin-4 induced 1-mediated resistance to an immune checkpoint inhibitor through suppression of CD8+ T cell infiltration in melanoma.
Cancer Sci., in press (2024) |
| 2024年1月24日 |
Yonemura, A., Semba, T., Zhang, J., Fan, Y., Yasuda-Yoshihara, N., Wang, H., Uchihara, T., Yasuda, T., Nishimura, A., Fu, L., Hu, X., Wei, F., Kitamura, F., Akiyama, T., Yamashita, K., Eto, K., Iwagami, S., Iwatsuki, M., Miyamoto, Y., Matsusaki, K., Yamasaki, J., Nagano, O., Saya, H., Song, S., Tan, P., Baba, H., Ajani, J. A. and Ishimoto, T. Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment.
Cell Rep, in press (2023) |
| 2024年1月22日 |
Tani, T., Mathsyaraja, H., Campisi, M., Li, Z. H., Haratani, K., Fahey, C. G., Ota, K., Mahadevan, N. R., Shi, Y., Saito, S., Mizuno, K., Thai, T. C., Sasaki, N., Homme, M., Yusuf, C. F. B., Kashishian, A., Panchal, J., Wang, M., Wolf, B. J., Barbie, T. U., Paweletz, C. P., Gokhale, P. C., Liu, D., Uppaluri, R., Kitajima, S., Cain, J. and Barbie, D. A. TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity.
Cancer Discov., in press (2024) |
| 2024年1月15日 |
Kimura, N., Tanaka, Y., Yamanishi, Y., Takahashi, A. and Sakuma, S. Nanoparticles based on natural-lipids reveal extent of impacts of designed physical characteristics on biological functions.
ACS Nano, in press (2024) |
| 2024年1月12日 |
Morino, S., Mashima, T., Shirai, F., Nagayama, S., Katayama, R. and Seimiya, H. BET protein–dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer.
Cancer Lett, in press (2024) |
| 2024年1月9日 |
Murayama, T., Nakayama, J., Jiang, X., Miyata, K., Morris, A. D., Cai, K. Q., Prasad, R. M., Ma, X., Efimov, A., Belani, N., Gerstein, E. R., Tan, Y., Zhou, Y., Kim, W., Maruyama, R., Campbell, K. S., Chen, L., Yang, Y., Balachandran, S. and Canadas, I. Targeting DHX9 triggers tumor-intrinsic interferon response and replication stress in small cell lung cancer.
Cancer Discov, in press (2024) |
