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Projects

Projects

  1. Histological criteria for effectiveness of chemo- and radio-therapy for gastrointestinal tumors
  2. Study of premalignant and in-situ carcinoma for Bile-duct and pancreas group
  3. Histopathological study towards selection of treatment modalities and outcome prediction in head and neck cancer
  4. Studies by Breast Group
  5. Hepatocarcinogenesis using experimental liver cancer models
  6. Pathological studies for gynecological malignancies
  7. Diagnostic and etiologic studies for lung cancers
  8. Clinicopathological studies with aids of chromosome analysis for genitourinary cancers
  9. Pathological and molecular studies for bone and soft tissue tumors
  10. Pathological and molecular studies for hematological neoplasms

Study of premalignant and in-situ carcinoma for Bile-duct and pancreas group

The bile-duct system and pancreas group
Members: Drs. Y. Kato, N. Yamamoto, M. Katori, T.Noro

The bile-duct system and pancreas group carries out pathological diagnosis of operation materials of tumors involved in bile ducts and pancreas. As research activities, we are elucidating the following themes.

  1. Study of premalignant and in-situ carcinomas.
    We analyze in-situ carcinomas (PanIN 3) histologically and molecular-biologically as compared with invasive ones and contribute to early detection of refractory carcinomas.
  2. Invasive carcinomas derived from intraductal papillary mucinous neoplasims (IPMN).
    It is known that invasive carcinomas derived from IPMN have better prognosis than usual invasive carcinomas. Under multi-institutional collaboration, we are examining histological criteria of invasion including minimal invasion.
  3. State of stroma and grade of malignancy.
    We investigate relationships between degree of development of stroma such as blood vessels and fibrous tissues and grade of malignancy.

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